Early Glaucoma Detection using Deep Learning with Multiple Datasets of Fundus Images

Rishiraj Paul Chowdhury; Nirmit Shekar Karkera

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arXiv · 2506.21770

Early Glaucoma Detection using Deep Learning with Multiple Datasets of Fundus Images

Rishiraj Paul Chowdhury·Nirmit Shekar Karkera

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Abstract

Glaucoma is a leading cause of irreversible blindness, but early detection can significantly improve treatment outcomes. Traditional diagnostic methods are often invasive and require specialized equipment. In this work, we present a deep learning pipeline using the EfficientNet-B0 architecture for glaucoma detection from retinal fundus images. Unlike prior studies that rely on single datasets, we sequentially train and fine-tune our model across ACRIMA, ORIGA, and RIM-ONE datasets to enhance generalization. Our experiments show that minimal preprocessing yields higher AUC-ROC compared to more complex enhancements, and our model demonstrates strong discriminative performance on unseen datasets. The proposed pipeline offers a reproducible and scalable approach to early glaucoma detection, supporting its potential clinical utility.

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Rishiraj Paul Chowdhury, Nirmit Shekar Karkera. 2025-06-26. Early Glaucoma Detection using Deep Learning with Multiple Datasets of Fundus Images. https://arxiv.org/abs/2506.21770

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