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arXiv · 2506.22334

Linking climate and dengue in the Philippines using a two-stage Bayesian spatio-temporal model

Stephen Jun Villejo·Sara Martino·Janine Illian
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Abstract

Dengue is an infectious disease which poses significant socioeconomic and disease burden in many tropical and subtropical regions of the world. This work aims to provide additional insight into the association between dengue and climate in the Philippines. We employ a two-stage modelling framework: the first stage fits climate models, while the second stage fits a health model that uses the climate predictions from the first stage as inputs. We postulate a Bayesian spatio-temporal model and use the integrated nested Laplace approximation (INLA) approach for inference. To account for the uncertainty in the climate models, we perform posterior sampling and then perform Bayesian model averaging to compute the final posterior estimates of second-stage model parameters. The results indicate that temperature is positively associated with dengue, although extremely hot conditions tend to have a negative effect. Moreover, the relationship between rainfall and dengue varies in space. In areas with uniform amounts of rainfall all year round, rainfall is negatively associated with dengue. In contrast, in regions with pronounced dry and wet season, rainfall shows a positive association with dengue. Finally, there remains unexplained structured variation in space and time after accounting for the impact of climate variables and other covariates.

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Stephen Jun Villejo, Sara Martino, Janine Illian. 2025-06-27. Linking climate and dengue in the Philippines using a two-stage Bayesian spatio-temporal model. https://arxiv.org/abs/2506.22334

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