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arXiv · 2508.05550

PhysiBoSS-Models: A database for multiscale models

Vincent Noel·Marco Ruscone·Randy Heiland·Arnau Montagud·Alfonso Valencia·Emmanuel Barillot·Paul Macklin·Laurence Calzone
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Abstract

PhysiBoSS is an open-source platform that integrates agent-based modeling of cell populations with intracellular stochastic Boolean networks, enabling multiscale simulations of complex biological behaviors. To promote model sharing and versioning, we present the PhysiBoSS-Models database: a curated repository for multiscale models built with PhysiBoSS. By providing a simple Python API, PhysiBoSS-Models provides an easy way to download and simulate preexisting models through tools such as PhysiCell Studio. By providing standardized access to validated models, PhysiBoSS-Models facilitates reuse, validation, and benchmarking, supporting research in biology.

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Vincent Noel, Marco Ruscone, Randy Heiland, Arnau Montagud, Alfonso Valencia, Emmanuel Barillot, Paul Macklin, Laurence Calzone. 2025-08-07. PhysiBoSS-Models: A database for multiscale models. https://arxiv.org/abs/2508.05550

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