Physics-Guided Null-Space Diffusion with Sparse Masking for Corrective Sparse-View CT Reconstruction

Zekun Zhou; Yanru Gong; Liu Shi; Qiegen Liu

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arXiv · 2509.05992

Physics-Guided Null-Space Diffusion with Sparse Masking for Corrective Sparse-View CT Reconstruction

Zekun Zhou·Yanru Gong·Liu Shi·Qiegen Liu

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Abstract

Diffusion models have demonstrated remarkable generative capabilities in image processing tasks. We propose a Sparse condition Temporal Rewighted Integrated Distribution Estimation guided diffusion model (STRIDE) for sparse-view CT reconstruction. Specifically, we design a joint training mechanism guided by sparse conditional probabilities to facilitate the model effective learning of missing projection view completion and global information modeling. Based on systematic theoretical analysis, we propose a temporally varying sparse condition reweighting guidance strategy to dynamically adjusts weights during the progressive denoising process from pure noise to the real image, enabling the model to progressively perceive sparse-view information. The linear regression is employed to correct distributional shifts between known and generated data, mitigating inconsistencies arising during the guidance process. Furthermore, we construct a dual-network parallel architecture to perform global correction and optimization across multiple sub-frequency components, thereby effectively improving the model capability in both detail restoration and structural preservation, ultimately achieving high-quality image reconstruction. Experimental results on both public and real datasets demonstrate that the proposed method achieves the best improvement of 2.58 dB in PSNR, increase of 2.37\% in SSIM, and reduction of 0.236 in MSE compared to the best-performing baseline methods. The reconstructed images exhibit excellent generalization and robustness in terms of structural consistency, detail restoration, and artifact suppression.

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Zekun Zhou, Yanru Gong, Liu Shi, Qiegen Liu. 2025-09-07. Physics-Guided Null-Space Diffusion with Sparse Masking for Corrective Sparse-View CT Reconstruction. https://arxiv.org/abs/2509.05992

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