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arXiv · 2601.15502

Optical Manipulation of Erythrocytes via Evanescent Waves: Assessing Glucose-Induced Mobility Variations

T. Troncoso Enríquez·J. Staforelli-Vivanco·I. Bordeu·M. González-Ortiz
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Abstract

This study investigates the dynamics of red blood cells (RBCs) under the influence of evanescent waves generated by total internal reflection (TIR). Using a 1064 nm laser system and a dual-chamber prism setup, we quantified the mobility of erythrocytes in different glucose environments. Our methodology integrates automated tracking via TrackMate\c{opyright} to analyze over 60 trajectory sets. The results reveal a significant decrease in mean velocity, from 11.8 {\mu}m/s in 5 mM glucose to 8.8 {\mu}m/s in 50 mM glucose (p = 0.019). These findings suggest that evanescent waves can serve as a non-invasive tool to probe the mechanical properties of cell membranes influenced by biochemical changes.

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T. Troncoso Enríquez, J. Staforelli-Vivanco, I. Bordeu, M. González-Ortiz. 2026-01-21. Optical Manipulation of Erythrocytes via Evanescent Waves: Assessing Glucose-Induced Mobility Variations. https://arxiv.org/abs/2601.15502

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