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arXiv · 2602.00074

Adoption and Use of LLMs at an Academic Medical Center

Abstract

While large language models (LLMs) can support clinical documentation needs, standalone tools struggle with "workflow friction" from manual data entry. We developed ChatEHR, a system that enables the use of LLMs with the entire patient timeline spanning several years. ChatEHR enables automations - which are static combinations of prompts and data that perform a fixed task - and interactive use in the electronic health record (EHR) via a user interface (UI). The resulting ability to sift through patient medical records for diverse use-cases such as pre-visit chart review, screening for transfer eligibility, monitoring for surgical site infections, and chart abstraction, redefines LLM use as an institutional capability. This system, accessible after user-training, enables continuous monitoring and evaluation of LLM use. In 1.5 years, we built 7 automations and 1075 users have trained to become routine users of the UI, engaging in 23,000 sessions in the first 3 months of launch. For automations, being model-agnostic and accessing multiple types of data was essential for matching specific clinical or administrative tasks with the most appropriate LLM. Benchmark-based evaluations proved insufficient for monitoring and evaluation of the UI, requiring new methods to monitor performance. Generation of summaries was the most frequent task in the UI, with an estimated 0.73 hallucinations and 1.60 inaccuracies per generation. The resulting mix of cost savings, time savings, and revenue growth required a value assessment framework to prioritize work as well as quantify the impact of using LLMs. Initial estimates are $6M savings in the first year of use, without quantifying the benefit of the better care offered. Such a "build-from-within" strategy provides an opportunity for health systems to maintain agency via a vendor-agnostic, internally governed LLM platform.

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Nigam H. Shah, Nerissa Ambers, Abby Pandya, Timothy Keyes, Juan M. Banda, Srikar Nallan, Carlene Lugtu, Artem A. Trotsyuk, Suhana Bedi, Alyssa Unell, Miguel Fuentes, Francois Grolleau, Sneha S. Jain, Jonathan Chen, Devdutta Dash, Danton Char, Aditya Sharma, Duncan McElfresh, Patrick Scully, Vishanthan Kumar, Clancy Dennis, Connor OBrien, Satchi Mouniswamy, Elvis Jones, Krishna Jasti, Gunavathi Mannika Lakshmanan, Sree Ram Akula, Varun Kumar Singh, Ramesh Rajmanickam, Sudhir Sinha, Vicky Zhou, Xu Wang, Bilal Mawji, Joshua Ge, Wencheng Li, Travis Lyons, Jarrod Helzer, Vikas Kakkar, Ramesh Powar, Darren Batara, Cheryl Cordova, William Frederick III, Olivia Tang, Phoebe Morgan, April S. Liang, Stephen P. Ma, Shivam Vedak, Dong-han Yao, Akshay Swaminathan, Mehr Kashyap, Brian Ng, Jamie Hellman, Nikesh Kotecha, Christopher Sharp, Gretchen Brown, Christian Lindmark, Anurang Revri, Michael A. Pfeffer. 2026-01-21. Adoption and Use of LLMs at an Academic Medical Center. https://arxiv.org/abs/2602.00074

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