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arXiv · 2606.14557

Private Information Retrieval for Large-Scale DNA-Based Data Storage

Gökberk Erdoğan·Daniella Bar-Lev·Rawad Bitar·Antonia Wachter-Zeh·Zohar Yakhini
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Abstract

We investigate Private Information Retrieval (PIR) in the context of synthetic DNA-based data storage. While PIR is a well-studied primitive for digital databases, extending it to DNA-based databases presents unique challenges arising from biochemical query mechanisms and their complexity. We propose two approaches for adapting two-server PIR protocols to DNA-based storage, balancing privacy, efficiency, and feasibility. These approaches illustrate how information-theoretic privacy trade-offs manifest in DNA-based storage systems.

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Gökberk Erdoğan, Daniella Bar-Lev, Rawad Bitar, Antonia Wachter-Zeh, Zohar Yakhini. 2026-06-12. Private Information Retrieval for Large-Scale DNA-Based Data Storage. https://arxiv.org/abs/2606.14557

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