Searcharxiv⌕ Search
Home/Archive/arXiv

arXiv · 2607.14023

Exact Decomposition of Adversarial Dual-Objective Value Functions, with Applications to Optimal Drug Dosing

Dylan Hirsch·William Sharpless·Sylvia Herbert
View original source ↗Read source document ↗Export metadata ↓

Abstract

Hamilton-Jacobi Reachability (HJR) is a central framework in safe control theory. While HJR has traditionally focused on a few fundamental tasks, there is increasing interest in scaling to more complex objectives. Recent works have studied the exact decomposition of the value functions for two fundamental dual-objective tasks in the adversary-free setting. However, not all value function decompositions in HJR remain valid with an adversary. In this work, we develop theoretical approaches to certify that for these two composite value functions, the proposed decompositions still hold with an adversary. Finally, we show how these results can solve issues that arise when applying HJR to optimal drug regimen design.

Explore related subjects

eess.SYcs.SYq-bio.QM

Keep this discovery

BibTeXRIS

Dylan Hirsch, William Sharpless, Sylvia Herbert. 2026-07-15. Exact Decomposition of Adversarial Dual-Objective Value Functions, with Applications to Optimal Drug Dosing. https://arxiv.org/abs/2607.14023

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related papers

arXiv2026

Structured Stochastic Representations of Integrated Dynamic Strategies

Dynamic allocation decisions couple present resource use to evolving internal conditions, delayed returns, and future costs. We represent this interaction by four probability localizations linked through regime-indexed, graph-constrained column-stochastic operators. Pre-action state or context selects a locally affine model, while action-dependent changes update subsequent regimes, yielding a causal switched representation of nonlinear evolution. We characterize operator identifiability relative to the graph, the stochastic constraints, and the sampled embedding, separating coefficient recovery from predictive equivalence on the decision domain. Decision making is then formulated through implementable return--cost acceptability regions. Finite-horizon error propagation supplies conservative classification margins, and simultaneous intervals distinguish model-relative near-optimality from certified $\epsilon$-optimality over a declared finite policy class. Regime-indexed stochastic feedback is admitted when it satisfies the same certification test. Reproducible synthetic laboratories for personal preparation, supplier participation, and customer retention illustrate exact, operator-supplied, and noisy feedback cases. Multinomial experiments show improving recovery of the feedback function and fewer unresolved decisions with increasing sample size, while unrestricted off-policy recovery remains limited. The contribution is a structure-preserving representation--identification--decision workflow, not a domain-specific physiological or commercial calibration.

eess.SY↗
arXiv2026

Fusion Estimation in Multi-sensor Systems for Data Packets with Disrupted Identities

In this paper, we explore the problem of fusion estimation for a multi-sensor system where the identity of the data packet received by each sensor may be disrupted or incorrect due to confusion in device identity allocation, communication protocol defects, or the lack of a clear sensor identifier. This can result in a random shuffle of the data components during the fusion estimation process, compromising the performance of the fusion estimation. To address this issue, we introduce the concepts of permutations and symmetry groups to describe this phenomenon as data packet permutation. We construct statistics to simplify the information set, developing two algorithms: a Bayesian approach, which performs fusion using posterior arrangement probabilities, and a greedy approach, which effectively improves estimation performance by guessing the likely data arrangement. We compare these two algorithms and demonstrate that both are expectation error-bounded. We improve algorithms for information-scarce scenarios. By employing the expectation-maximization algorithm, we fill in the prior information of data arrangement where the correct convergence is proven. Finally, we present numerical simulations to validate our results.

eess.SY↗
arXiv2026

Quantifying the Reality Gap for RL-Based UAV Placement at mmWave and Sub-THz

Reinforcement learning (RL) policies for unmanned aerial vehicle (UAV) placement in mmWave and sub-terahertz networks are typically trained on simplified analytical channels. We quantify the resulting sim-to-real gap on a real urban map of Doha, Qatar, at carriers {28, 140, 183, 300} GHz and altitudes {50, 75, 100, 125} m, evaluating three channel pipelines: an analytical model (FSPL + atmospheric absorption + cuboid LoS), full Monte-Carlo ray tracing in Sionna RT with ITU-R P.676-13 absorption, and a deterministic-LoS hybrid that reuses Sionna's mesh under a closed-form path-gain expression. We formalize the gap on the spatial SNR distribution via four metrics, namely bias, RMSE, Jensen-Shannon divergence, and optimum-deployment displacement. Three findings emerge: at 28/140 GHz, $\sim$70% of the apparent -5.6/-4.8 dB Sionna bias is Monte-Carlo undersampling and shrinks to -1.7/-1.5 dB after mitigation; at 183 GHz a -9.2 dB residual isolates the atmospheric absorption / ITU-R P.676 line-shape disagreement; at 300 GHz the stochastic ray tracer agrees with the analytical model only coincidentally, with a +3.8 dB structural offset exposed by the deterministic-LoS pipeline. Across all carriers the linear-domain regret of the analytical-trained policy stays $\geq$ 0.93, indicating practical near-optimality but with a carrier-resolved SNR bias that warrants explicit reporting.

eess.SY↗