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arXiv · 2608.08163

Agentic AI-driven Immersive Simulation: A Knowledge-Aware Virtual Training Platform forHigh Dose Rate (HDR) Brachytherapy

Ronghua Xu·Kepha Barasa·Manoj Kumal·Xinyun Liu·Weihua Zhou·Xin Qian
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Abstract

The convergence of the Metaverse and Large Language Model (LLM)-based AI agent is catalyzing a shift toward autonomous, immersive, and personalized pedagogical frameworks in medical education. This paper presents a novel agentic AI-driven immersive simulation specifically designed for High Dose Rate (HDR) vaginal cylinder (VC) brachytherapy in cancer care. By integrating Virtual Reality (VR) and mobile computing, the system establishes a high-fidelity, risk-free environment that allows trainees to master complex procedural skills without the facility or safety constraints posed by physical anatomy or live radioactive sources. A core contribution of this work is the seamless integration of a knowledge-aware assistant leveraging Retrieval-Augmented Generation (RAG) to ground agent interactions in authoritative clinical guidelines. This architecture also enables an interactive agent to provide natural language interfaces and hands-free, real-time guidance during intricate medical maneuvers. We validate the proposed system through a prototype deployment comprising a Meta Quest 3 interface linked to a local GPU-accelerated AI backend, demonstrating a feasible architecture for HDR brachytherapy simulation. Experimental results indicate that the system maintains suitable end-to-end latency and high context precision, answer completeness, and relevance in the RAG-enhanced pedagogical support.

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Ronghua Xu, Kepha Barasa, Manoj Kumal, Xinyun Liu, Weihua Zhou, Xin Qian. 2026-08-08. Agentic AI-driven Immersive Simulation: A Knowledge-Aware Virtual Training Platform forHigh Dose Rate (HDR) Brachytherapy. https://arxiv.org/abs/2608.08163

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