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arXiv · 2608.23613

A nonlinear dynamics approach to assess amplitude-frequency coupling in non-invasive human electrogastrography recordings

Akshita A. Rao·Todd P. Coleman
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Abstract

Conventional electrogastrography (EGG) analyses summarize gastric slow-wave activity using dominant frequency, power, or phase-based metrics, without explicitly modeling amplitude-dependent frequency dynamics. We developed a statistical nonlinear-dynamics framework that represents the gastric-band analytic EGG signal as a stochastic Stuart-Landau oscillator and estimate local effective phase-shear, $\beta_{\mathrm{eff}}$, a normalized measure of amplitude-frequency coupling. In overnight recordings from 60 healthy participants, effective phase-shear was consistently negative, generalized to held-out halves of each recording, and was abolished by amplitude surrogates that disrupted amplitude-phase alignment while preserving amplitude-series structure. We then applied the measure to fasted and fed recordings from 16 healthy participants and 24 participants with gastric dysfunction. Phase-shear magnitude differed between groups and classified dysfunction comparable to the strongest multielectrode phase-based traveling-wave measures. These findings establish amplitude-frequency coupling as a dynamical feature of gastric-band EGG that complements conventional spectral and spatial phase metrics, while motivating future multichannel observation models to determine its relationship to slow-wave propagation and gastric function.

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Akshita A. Rao, Todd P. Coleman. 2026-08-21. A nonlinear dynamics approach to assess amplitude-frequency coupling in non-invasive human electrogastrography recordings. https://arxiv.org/abs/2608.23613

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