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arXiv · 2609.13213

A Stochastic Model of Intracellular Calcium Concentrations

Tomás Caraballo·Macarena Gómez-Mármol·Ignacio Roldán
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Abstract

In this paper, we study a slow-fast model of Intracellular Calcium Concentrations (ICC) within a stochastic framework, where stochastic perturbations are introduced to capture the intrinsic randomness of such biological systems. We first analyse the three-dimensional single-cell model, based on the FitzHugh-Nagumo structure, and subsequently extend the analysis to a coupled two-cell six-dimensional setting. We prove existence and uniqueness of solutions and establish positivity of the calcium variable. We obtain explicit mean-square stability estimates around deterministic equilibria and quantify how they depend on the noise intensity. Numerical simulations for both the single-cell and coupled systems illustrate relevant qualitative behaviours and reveal additional dynamical features arising in the stochastic framework.

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Tomás Caraballo, Macarena Gómez-Mármol, Ignacio Roldán. 2026-08-26. A Stochastic Model of Intracellular Calcium Concentrations. https://arxiv.org/abs/2609.13213

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