Transport of Deformable Vesicles Driven by Chiral Active Brownian Particles

Abstract

Active matter systems can generate mechanical stresses that deform their surroundings, providing a route to transport and shape dynamics far from equilibrium. Deformable vesicles containing active particles offer a minimal setting in which such active stresses are directly coupled to boundary mechanics. Here, we use numerical simulations to investigate a two-dimensional, fixed-area vesicle filled with chiral active particles interacting through excluded volume and polar alignment. We find that the coupling between particle chirality and vesicle deformation produces distinct modes of collective motion, including run-and-tumble-like migration, rotor-like dynamics, and persistent spinning. Most notably, we show that vesicle rotation is non-monotonic in chirality: at fixed activity, an optimal chirality maximizes the rotational velocity. We develop an analytical theory that relates the vesicle rotation to the effective torque generated by the chiral active particles. The theory identifies the competition underlying the optimal chirality and predicts a scale-invariant dependence of the rotational velocity on activity and chirality. This scaling collapses simulation results obtained over different activity strengths onto a universal curve. Our results establish a general mechanism by which chirality and collective alignment regulate the transmission of active stresses to deformable boundaries, providing a framework for understanding transport and rotational dynamics in confined active systems.