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Dynamic concentration of motors in microtubule arrays

Francois Nedelec·Thomas Surrey·A. C. Maggs
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Abstract

We present experimental and theoretical studies of the dynamics of molecular motors in microtubule arrays and asters. By solving a convection-diffusion equation we find that the density profile of motors in a two-dimensional aster is characterized by continuously varying exponents. Simulations are used to verify the assumptions of the continuum model. We observe the concentration profiles of kinesin moving in quasi two-dimensional artificial asters by fluorescent microscopy and compare with our theoretical results.

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Francois Nedelec, Thomas Surrey, A. C. Maggs. 2001-01-15. Dynamic concentration of motors in microtubule arrays. https://doi.org/10.1103/physrevlett.86.3192

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