Searcharxiv⌕ Search
Home/Archive/arXiv

arXiv · cond-mat/0107576

Green fluorescent proteins as optically-controllable elements in bioelectronics

Riccardo A. G. Cinelli·Vittorio Pellegrini·Aldo Ferrari·Paolo Faraci·Riccardo Nifosi'·Mudit Tyagi·Mauro Giacca·Fabio Beltram
View original source ↗Read source document ↗Export metadata ↓

Abstract

A single-biomolecule optical toggle-switch is demonstrated based on a mutated green fluorescent protein (GFP). We have exploited molecular biology techniques to tailor GFP molecular structure and photophysical properties and give it optically-controlled bistability between two distinct states. We present optical control of the fluorescence dynamics with two laser beams at 476 and 350 nm down to the ultimate limit of single molecules. These results indicate that GFP-class fluorophores are promising candidates for the realization of biomolecular devices such as volumetric optical memories and optical switches.

Explore related subjects

cond-matq-bio

Keep this discovery

BibTeXRIS

Riccardo A. G. Cinelli, Vittorio Pellegrini, Aldo Ferrari, Paolo Faraci, Riccardo Nifosi', Mudit Tyagi, Mauro Giacca, Fabio Beltram. 2001-07-27. Green fluorescent proteins as optically-controllable elements in bioelectronics. https://doi.org/10.1063/1.1419047

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related papers

arXiv2017

Random-Matrix Theory of Quantum Size Effects on Nuclear Magnetic Resonance in Metal Particles

The distribution function of the local density of states is computed exactly for the Wigner-Dyson ensemble of random Hamiltonians. In the absence of time-reversal symmetry, precise agreement is obtained with the "supersymmetry" theory by Efetov and Prigodin of the NMR lineshape in disordered metal particles. Upon breaking time-reversal symmetry, the variance of the Knight shift in the smallest particles is reduced by a universal factor of 2/3. ***To be published in Physical Review B.****

cond-mat↗
arXiv2017

Andreev Reflection In Ferromagnet-Superconductor Junctions

The transport properties of a ferromagnet-superconductor (FS) junction are studied in a scattering formulation. Andreev reflection at the FS interface is strongly affected by the exchange interaction in the ferromagnet. The conductance G_FS of a ballistic point contact between F and S can be both larger or smaller than the value G_FN with the superconductor in the normal state, depending on the ratio of the exchange and Fermi energies. If the ferromagnet contains a tunnel barrier (I), the conductance G_FIFS exhibits resonances which do not vanish in linear response -- in contrast to the Tomasch oscillations for non-ferromagnetic materials.

cond-mat↗
arXiv2017

Long-Range Energy-Level Interaction in Small Metallic Particles

We consider the energy level statistics of non-interacting electrons which diffuse in a $ d $-dimensional disordered metallic conductor of characteristic Thouless energy $ E_c. $ We assume that the level distribution can be written as the Gibbs distribution of a classical one-dimensional gas of fictitious particles with a pairwise additive interaction potential $ f(\varepsilon ). $ We show that the interaction which is consistent with the known correlation function of pairs of energy levels is a logarithmic repulsion for level separations $ \varepsilon E_c, $ $ f(\varepsilon ) $ vanishes as a power law in $ \varepsilon /E_c $ with exponents $ -{1 \over 2},-2, $ and $ -{3 \over 2} $ for $ d=1,2, $ and 3, respectively. While for $ d=1,2 $ the energy-level interaction is always repulsive, in three dimensions there is long-range level attraction after the short-range logarithmic repulsion.

cond-mat↗