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Protein crystallization in confined geometries

S. Tanaka·S. U. Egelhaaf·W. C. K. Poon
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Abstract

We studied the crystallization of a globular protein, lysozyme, in the cubic phase of the lipid monoolein. The solubility of lysozyme in salt solution decreased by a factor of $\sim 4$ when confined in cubic phase. Calculations and Monte Carlo simulations show that this can be explained by the {\it confinement} of lysozyme molecules to the narrow water cells in the cubic phase.

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S. Tanaka, S. U. Egelhaaf, W. C. K. Poon. 2003-09-16. Protein crystallization in confined geometries. https://arxiv.org/abs/cond-mat/0309373

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