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Optimal target search on a fast folding polymer chain with volume exchange

Michael A. Lomholt·Tobias Ambjornsson·Ralf Metzler
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Abstract

We study the search process of a target on a rapidly folding polymer (`DNA') by an ensemble of particles (`proteins'), whose search combines 1D diffusion along the chain, Levy type diffusion mediated by chain looping, and volume exchange. A rich behavior of the search process is obtained with respect to the physical parameters, in particular, for the optimal search.

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Michael A. Lomholt, Tobias Ambjornsson, Ralf Metzler. 2006-01-06. Optimal target search on a fast folding polymer chain with volume exchange. https://doi.org/10.1103/physrevlett.95.260603

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