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Behavior of tumors under nonstationary theraphy

O. Sotolongo-Costa·L. Morales Molina·D. Rodriguez Perez·J. C. Antoranz·M. Chacon Reyes
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Abstract

We present a model for the interaction dynamics of lymphocytes-tumor cells population. This model reproduces all known states for the tumor. Futherly,we develop it taking into account periodical immunotheraphy treatment with cytokines alone. A detailed analysis for the evolution of tumor cells as a function of frecuency and theraphy burden applied for the periodical treatment is carried out. Certain threshold values for the frecuency and applied doses are derived from this analysis. So it seems possible to control and reduce the growth of the tumor. Also, constant values for cytokines doses seems to be a succesful treatment.

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O. Sotolongo-Costa, L. Morales Molina, D. Rodriguez Perez, J. C. Antoranz, M. Chacon Reyes. 2002-04-26. Behavior of tumors under nonstationary theraphy. https://doi.org/10.1016/s0167-2789(03)00005-8

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