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Defibrillation via the Elimination of Spiral Turbulence in a Model for Ventricular Fibrillation

Sitabhra Sinha·Ashwin Pande·Rahul Pandit
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Abstract

Ventricular fibrillation, the major reason behind sudden cardiac death, is turbulent cardiac electrical activity in which rapid, irregular disturbances in the spatiotemporal electrical activation of the heart makes it incapable of any concerted pumping action. Methods of controlling ventricular fibrillation include electrical defibrillation as well as injected medication. Electrical defibrillation, though widely used, involves subjecting the whole heart to massive, and often counterproductive, electrical shocks. We propose a defibrillation method that uses a very-low-amplitude shock (of order mV) applied for a brief duration (of order 100 ms) and over a coarse mesh of lines on our model ventricle.

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Sitabhra Sinha, Ashwin Pande, Rahul Pandit. 2001-04-04. Defibrillation via the Elimination of Spiral Turbulence in a Model for Ventricular Fibrillation. https://doi.org/10.1103/physrevlett.86.3678

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