Melting Transition of Directly-Linked Gold Nanoparticle DNA Assembly

Y. Sun; N. C. Harris; C. -H. Kiang

doi:10.1016/j.physa.2005.01.013

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Melting Transition of Directly-Linked Gold Nanoparticle DNA Assembly

Y. Sun·N. C. Harris·C. -H. Kiang

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Abstract

DNA melting and hybridization is a fundamental biological process as well as a crucial step in many modern biotechnology applications. DNA confined on surfaces exhibits different behavior from that in free solutions. The system of DNA-capped gold nanoparticles exhibits unique phase transitions and represents a new class of complex fluids. Depending on the sequence of the DNA, particles can be linked to each other through direct complementary DNA sequences or via a ``linker'' DNA whose sequence is complementary to the sequence attached to the gold nanoparticles. We observed different melting transitions for these two distinct systems.

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Y. Sun, N. C. Harris, C. -H. Kiang. 2005-03-10. Melting Transition of Directly-Linked Gold Nanoparticle DNA Assembly. https://doi.org/10.1016/j.physa.2005.01.013

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