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Searching low-energy conformations of two elastin sequences

H. Arkin
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Abstract

The three-dimensional structures of two common repeat motifs Val$^1$-Pro$^2$-Gly$^3$-Val$^4$-Gly$^5$ and Val$^1$-Gly$^2$-Val$^3$-Pro$^4$-Gly$^5$-Val$^6$-Gly$^7$-Val$^8$-Pro$^9$ of tropoelastin are investigated by using the multicanonical simulation procedure. By minimizing the energy structures along the trajectory the thermodynamically most stable low-energy microstates of the molecule are determined. The structural predictions are in good agreement with X-ray diffraction experiments.

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H. Arkin. 2004-04-04. Searching low-energy conformations of two elastin sequences. https://doi.org/10.1140/epjb%2Fe2004-00050-0

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