What one can learn from experiments about the elusive transition state?

Iksoo Chang; Marek Cieplak; Jayanth R. Banavar; Amos Maritan

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What one can learn from experiments about the elusive transition state?

Iksoo Chang·Marek Cieplak·Jayanth R. Banavar·Amos Maritan

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Abstract

We present the results of an exact analysis of a model energy landscape of a protein to clarify the notion of the transition state and the physical meaning of the $ϕ$ values determined in protein engineering experiments. We benchmark our findings to various theoretical approaches proposed in the literature for the identification and characterization of the transition state.

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Iksoo Chang, Marek Cieplak, Jayanth R. Banavar, Amos Maritan. 2004-05-18. What one can learn from experiments about the elusive transition state?. https://arxiv.org/abs/q-bio/0405013

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