Role of calcium and noise in the persistent activity of an isolated neuron

Simona Cocco

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arXiv · q-bio/0406010

Role of calcium and noise in the persistent activity of an isolated neuron

Simona Cocco

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Abstract

The activity of an isolated and auto-connected neuron is studied using Hodgkin--Huxley and Integrate-and-Fire frameworks. Main ingredients of the modeling are the auto-stimulating autaptic current observed in experiments, with a spontaneous synaptic liberation noise and a calcium--dependent negative feedback mechanism. The distributions of inter-spikes intervals and burst durations are analytically calculated, and show a good agreement with experimental data.

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Simona Cocco. 2004-06-03. Role of calcium and noise in the persistent activity of an isolated neuron. https://arxiv.org/abs/q-bio/0406010

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