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Min-protein oscillations in Escherichia coli with spontaneous formation of two-stranded filaments in a three-dimensional stochastic reaction-diffusion model

Nenad Pavin·Hana Cipcic Paljetak·Vladimir Krstic
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Abstract

We introduce a three-dimensional stochastic reaction-diffusion model to describe MinD/MinE dynamical structures in Escherichia coli. This model spontaneously generates pole-to-pole oscillations of the membrane-associated MinD proteins, MinE ring, as well as filaments of the membrane-associated MinD proteins. Experimental data suggest MinD filaments are two-stranded. In order to model them we assume that each membrane-associated MinD protein can form up to three bonds with adjacent membrane associated MinD molecules and that MinE induced hydrolysis strongly depends on the number of bonds MinD has established.

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Nenad Pavin, Hana Cipcic Paljetak, Vladimir Krstic. 2006-02-14. Min-protein oscillations in Escherichia coli with spontaneous formation of two-stranded filaments in a three-dimensional stochastic reaction-diffusion model. https://doi.org/10.1103/physreve.73.021904

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