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Collective dynamics of molecular motors pulling on fluid membranes

O. Campas·Y. Kafri·K. B. Zeldovich·J. Casademunt·J. -F. Joanny
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Abstract

The collective dynamics of $N$ weakly coupled processive molecular motors are considered theoretically. We show, using a discrete lattice model, that the velocity-force curves strongly depend on the effective dynamic interactions between motors and differ significantly from a simple mean field prediction. They become essentially independent of $N$ if it is large enough. For strongly biased motors such as kinesin this occurs if $N\gtrsim 5$. The study of a two-state model shows that the existence of internal states can induce effective interactions.

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O. Campas, Y. Kafri, K. B. Zeldovich, J. Casademunt, J. -F. Joanny. 2005-12-08. Collective dynamics of molecular motors pulling on fluid membranes. https://doi.org/10.1103/physrevlett.97.038101

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