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A. A. Kozlov

Publications and source records attributed to A. A. Kozlov.

3 recordsLinked to original sources

On physical nature of radiation regulating quantity of cells in population

It is shown, that spontaneous ultraviolet radiation of cells (infusoria) plays the role of agent, restricting the upper limit of the quantity of cells in quasi-stationary phase of cultire's development. The spectral region of this radiation defined experimentally occurred to be in the range of 200-290 nm. As the filter cutting off the short wave length part of the spectrum (below 290nm) 1 mm thick plexiglas has been used, while as the filters transmitting short wave part of the spectrum - 5 mkm thick fluorostatic film or 1 mm thick optical quartz has been selected. It has been shown, that dynamics of development of the cells in the culture depends on transparency of nutrient medium to spontaneous ultraviolet radiation of the cells. Conclusion has been made, that superweak chemiluminescence of the cells is not a worthless metabolism product, but plays significant biological role.

physics.bio-ph

Autoregulation of the total number of cells in culture

According to the universally accepted concept of the development of life on the Earth, multicellular organisms initially emerged as a result of either the union of identical unicellular organisms with the following functional differentiation, or the union of symbionts, in which there already was a certain simple functional separation. However, in either case the progenitors of multicellular organisms were ensembles, communities of unicellular organisms. For a certain number of unicellular organisms to be treated as an ensemble, there must be some interconnection between its members. Colonies of mechanically connected unicellular organisms were a later, more advanced stage; here, unicellular organisms living separately are considered. Such interconnection must, in particular, limit from above the total numbers of the members of the ensemble, because an excessive increase in these numbers could disturb the connections between members of the ensemble to the extent of its destruction. In addition, too large numbers of members in the ensemble could lead to nutrient depletion in its habitat. One can assume that such interconnection between unicellular organisms was evolutionarily developed and genetically fixed. I assumed that modern unicellular organisms retain such an ability to regulate their total numbers. The validity of this assumption was tested in experiments, whose results are presented in this paper.

physics.bio-ph

Treatment of skin deseases in humans by a new method

The original method of treatment of various pathological processes in human skin covers is described. The method has a brightly expressed differential action: destroying pathologic cells it does not render any influence on healthy cells. The examples of application of a method for treatment of some kinds of skin pathologies are given.

physics.bio-ph