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A. N. Morozov

Publications and source records attributed to A. N. Morozov.

17 recordsLinked to original sources

Low-frequency gravitational waves coupled with electromagnetic waves in material media

The influence of the low-frequency gravitational waves coupled with electromagnetic waves in material media on the test masses is investigated. The propagation of coupled gravitational waves in rarefied gases and cold magnetized plasma is considered. It has been shown that under specific conditions the amplitude of the coupled gravitational waves in a media reaches values of the order of the amplitude of transverse gravitational waves from external astrophysical sources. The specific properties of longitudinal gravitational waves coupled with electromagnetic waves in a medium in relation to transverse gravitational waves from external sources are considered as well.

gr-qc

Clifford algebras and liquid crystalline fermions

We show that Clifford algebras provide a natural language to describe the physics of liquid crystal defects in 3D. This framework shows that most of these defects have fermionic nature, as the director field profile on a 2D cross section can algebraically be represented by a spinor. Defects in uniaxial, biaxial nematics and cholesterics are represented by elements belonging to different Clifford algebras, suggesting that there are fundamental distinctions between topological defects in each of these phases. Our theory allows nematic defects to be interpreted as Majorana-like spinors, as defects and antidefects are topologically equivalent, whilst some cholesteric defects, such as screw dislocations, are better viewed as Weyl-like spinors of well-defined chirality. Defects can be described by a ``defect bivector'', an algebraic element which quantifies the rototranslation associated with them. In cholesterics, fermionic defects of different types can combine to yield composite quasiparticles with either fermionic or bosonic nature. Under cylindrical confinement, these quasiparticles provide the way to understand the structure of screw dislocations. In the bulk, they may condensate to form topological phases, such as blue phases or skyrmion lattices. Our results provide a surprising link between liquid crystals, particle physics, and topological quantum matter.

cond-mat.soft

Extrusion without a motor: a new take on the loop extrusion model of genome organization

Chromatin loop extrusion is a popular model for the formation of CTCF loops and topological domains. Recent HiC data have revealed a strong bias in favour of a particular arrangement of the CTCF binding motifs that stabilize loops, and extrusion is the only model to date which can explain this. However, the model requires a motor to generate the loops, and although cohesin is a strong candidate for the extruding factor, a suitable motor protein (or a motor activity in cohesin itself) has yet to be found. Here we explore a new hypothesis: that there is no motor, and thermal motion within the nucleus drives extrusion. Using theoretical modelling and computer simulations we ask whether such diffusive extrusion could feasibly generate loops. Our simulations uncover an interesting ratchet effect (where an osmotic pressure promotes loop growth), and suggest, by comparison to recent in vitro and in vivo measurements, that diffusive extrusion can in principle generate loops of the size observed in the data. Extra View on : C. A. Brackley, J. Johnson, D. Michieletto, A. N. Morozov, M. Nicodemi, P. R. Cook, and D. Marenduzzo "Non-equilibrium chromosome looping via molecular slip-links", Physical Review Letters 119, 138101 (2017)

physics.bio-ph

Bound gravitational waves in a dielectric medium and a constant magnetic field

A description is made of the process of excitation of bound longitudinal-transverse gravitational waves during the propagation of electromagnetic waves in a dielectric medium. It is shown that the speed of such gravitational waves is less than the speed of light in a vacuum and coincides with the speed of an electromagnetic wave in matter. A description of the propagation of a bound gravitational waves in a dielectric in the presence of a constant magnetic field is suggested as well. It is claimed that these gravitational waves in a dielectric medium are forced ones and they cannot exist in a free state.

gr-qc

On the gravitational waves coupled with electromagnetic waves

A description is made of the process of excitation of coupled longitudinal-transverse gravitational waves during the propagation of a strong electromagnetic wave in a vacuum and when a standing electromagnetic wave exists in the Fabry-Perot resonator. It is shown that such waves lead to the appearance of transverse gravitational waves in empty space. It was established that two standing high-frequency electromagnetic waves in a Fabry-Perot resonator with close frequencies cause the appearance of a low-frequency transverse gravitational wave in empty space.

gr-qc

Rheology and microrheology of deformable droplet suspensions

Dense suspensions of soft colloidal particles display a broad range of physical and rheological properties which are still far from being fully understood. To elucidate the role of deformability on colloidal flow, we employ computer simulations to measure the apparent viscosity of a system of droplets of variable surface tension subjected to a pressure-driven flow. We confirm that our suspension generically undergoes discontinuous shear thinning, and determine the dependence of the onset of the discontinuity on surface tension. We find that the effective viscosity of the suspension is mainly determined by a capillary number. We present active microrheology simulations, where a single droplet is dragged through the suspension. These also show a dynamical phase transition, analogous to the one associated with discontinuous shear thinning in our interpretation. Such a transition is signalled by a discontinuity in the droplet velocity versus applied force.

cond-mat.soft

Flow of deformable droplets: discontinuous shear thinning and velocity oscillations

We study the rheology of a suspension of soft deformable droplets subjected to a pressure-driven flow. Through computer simulations, we measure the apparent viscosity as a function of droplet concentration and pressure gradient, and provide evidence of a discontinuous shear thinning behaviour, which occurs at a concentration-dependent value of the forcing. We further show that this response is associated with a nonequilibrium transition between a `hard' (or less deformable) phase, which is nearly jammed and flows very slowly, and a `soft' (or more deformable) phase, which flows much more easily. The soft phase is characterised by flow-induced time dependent shape deformations and internal currents, which are virtually absent in the hard phase. Close to the transition, we find sustained oscillations in both the droplet and fluid velocities. Polydisperse systems show similar phenomenology but with a smoother transition, and less regular oscillations.

cond-mat.soft

Non-equilibrium chromosome looping via molecular slip-links

We propose a model for the formation of chromatin loops based on the diffusive sliding of a DNA-bound factor which can dimerise to form a molecular slip-link. Our slip-links mimic the behaviour of cohesin-like molecules, which, along with the CTCF protein, stabilize loops which organize the genome. By combining 3D Brownian dynamics simulations and 1D exactly solvable non-equilibrium models, we show that diffusive sliding is sufficient to account for the strong bias in favour of convergent CTCF-mediated chromosome loops observed experimentally. Importantly, our model does not require any underlying, and energetically costly, motor activity of cohesin. We also find that the diffusive motion of multiple slip-links along chromatin may be rectified by an intriguing ratchet effect that arises if slip-links bind to the chromatin at a preferred "loading site". This emergent collective behaviour is driven by a 1D osmotic pressure which is set up near the loading point, and favours the extrusion of loops which are much larger than the ones formed by single slip-links.

physics.bio-ph

A 1-dimensional statistical mechanics model for nucleosome positioning on genomic DNA

The first level of folding of DNA in eukaryotes is provided by the so called '10 nm chromatin fibre', where DNA wraps around histone proteins (approx. 10 nm in size) to form nucleosomes, which go on to create a zig zagging bead on a string structure. In this work we present a 1 dimensional statistical mechanics model to study nucleosome positioning within one such 10 nm fibre. We focus on the case of genomic sheep DNA, and we start from effective potentials valid at infinite dilution and determined from high resolution in vitro salt dialysis experiments. We study positioning within a polynucleosome chain, and compare the results for genomic DNA to that obtained in the simplest case of homogeneous DNA, where the problem can be mapped to a Tonks gas. First, we consider the simple, analytically solvable, case where nucleosomes are assumed to be point like. Then, we perform numerical simulations to gauge the effect of their finite size on the nucleosomal distribution probabilities. Finally we compare nucleosome distributions and simulated nuclease digestion patterns for the two cases (homogeneous and sheep DNA), thereby providing testable predictions of the effect of sequence on experimentally observable quantities in experiments on polynucleosome chromatin fibres reconstituted in vitro.

physics.bio-ph

Filling an emulsion drop with motile bacteria

We have measured the spatial distribution of motile Escherichia coli inside spherical water droplets emulsified in oil. At low cell concentrations, the cell density peaks at the water-oil interface; at increasing concentration, the bulk of each droplet fills up uniformly while the surface peak remains. Simulations and theory show that the bulk density results from a `traffic' of cells leaving the surface layer, increasingly due to cell-cell scattering as the surface coverage rises above $\sim 10\%$. Our findings show similarities with the physics of a rarefied gas in a spherical cavity with attractive walls.

cond-mat.soft

Models for twistable elastic polymers in Brownian dynamics, and their implementation for LAMMPS

An elastic rod model for semi-flexible polymers is presented. Theory for a continuum rod is reviewed, and it is shown that a popular discretised model used in numerical simulations gives the correct continuum limit. Correlation functions relating to both bending and twisting of the rod are derived for both continuous and discrete cases, and results are compared with numerical simulations. Finally, two possible implementations of the discretised model in the multi-purpose molecular dynamics software package LAMMPS are described.

physics.bio-ph

Bulk rheology and microrheology of active fluids

We simulate macroscopic shear experiments in active nematics and compare them with microrheology simulations where a spherical probe particle is dragged through an active fluid. In both cases we define an effective viscosity: in the case of bulk shear simulations this is the ratio between shear stress and shear rate, whereas in the microrheology case it involves the ratio between the friction coefficient and the particle size. We show that this effective viscosity, rather than being solely a property of the active fluid, is affected by the way chosen to measure it, and strongly depends on details such as the anchoring conditions at the probe surface and on both the system size and the size of the probe particle.

cond-mat.soft

Phase separation and rotor self-assembly in active particle suspensions

Adding a non-adsorbing polymer to passive colloids induces an attraction between the particles via the `depletion' mechanism. High enough polymer concentrations lead to phase separation. We combine experiments, theory and simulations to demonstrate that using active colloids (such as motile bacteria) dramatically changes the physics of such mixtures. First, significantly stronger inter-particle attraction is needed to cause phase separation. Secondly, the finite size aggregates formed at lower inter-particle attraction show unidirectional rotation. These micro-rotors demonstrate the self assembly of functional structures using active particles. The angular speed of the rotating clusters scales approximately as the inverse of their size, which may be understood theoretically by assuming that the torques exerted by the outermost bacteria in a cluster add up randomly. Our simulations suggest that both the suppression of phase separation and the self assembly of rotors are generic features of aggregating swimmers, and should therefore occur in a variety of biological and synthetic active particle systems.

cond-mat.soft

Orientations of the lamellar phase of block copolymer melts under oscillatory shear flow

We develop a theory to describe the reorientation phenomena in the lamellar phase of block copolymer melt under reciprocating shear flow. We show that similar to the steady-shear, the oscillating flow anisotropically suppresses fluctuations and gives rise to the parallel-perpendicular orientation transition. The experimentally observed high-frequency reverse transition is explained in terms of interaction between the melt and the shear-cell walls.

cond-mat.soft

Influence of confinement on the orientational phase transitions in the lamellar phase of a block copolymer melt under shear flow

In this work we incorporate some real-system effects into the theory of orientational phase transitions under shear flow (M. E. Cates and S. T. Milner, Phys. Rev. Lett. v.62, p.1856 (1989) and G. H. Fredrickson, J. Rheol. v.38, p.1045 (1994)). In particular, we study the influence of the shear-cell boundaries on the orientation of the lamellar phase. We predict that at low shear rates the parallel orientation appears to be stable. We show that there is a critical value of the shear rate at which the parallel orientation loses its stability and the perpendicular one appears immediately below the spinodal. We associate this transition with a crossover from the fluctuation to the mean-field behaviour. At lower temperatures the stability of the parallel orientation is restored. We find that the region of stability of the perpendicular orientation rapidly decreases as shear rate increases. This behaviour might be misinterpreted as an additional perpendicular to parallel transition recently discussed in literature.

cond-mat.soft

Phase behaviour of block copolymer melts with arbitrary architecture

The Leibler theory [L. Leibler, Macromolecules, v.13, 1602 (1980)] for microphase separation in AB block copolymer melts is generalized for systems with arbitrary topology of molecules. A diagrammatic technique for calculation of the monomeric correlation functions is developed. The free energies of various mesophases are calculated within the second-harmonic approximation. Model highly-branched tree-like structures are considered as an example and their phase diagrams are obtained. The topology of molecules is found to influence the spinodal temperature and asymmetry of the phase diagrams, but not the types of phases and their order. We suggest that all model AB block-copolymer systems will exhibit the typical phase behaviour.

cond-mat.soft

Orientational phase transitions in the hexagonal phase of a diblock copolymer melt under shear flow

We generalize the earlier theory by Fredrickson [J. Rheol. v.38, 1045 (1994)] to study the orientational behaviour of the hexagonal phase of diblock copolymer melt subjected to steady shear flow. We use symmetry arguments to show that the orientational ordering in the hexagonal phase is a much weaker effect than in the lamellae. We predict the parallel orientation to be stable at low and the perpendicular orientation at high shear rates. Our analysis reproduces the experimental results by Tepe et al. [Macromolecules v.28, 3008 (1995)] and explains the difficulties in experimental observation of the different orientations in the hexagonal phase.

cond-mat.soft