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A. Sanna

Publications and source records attributed to A. Sanna.

At least 55 records · Page 3Linked to original sources

Quantitative characterization of amyloid deposits in murine models of alzheimer disease by phase-contrast x-ray imaging

Alzheimer's is a neurodegenerative disease that is the most common form of dementia, but there is still no definitive cure for this disease. The noninvasive X-ray Phase Contrast Tomography (XPCT) imaging technique was used to study brain tissues in mouse models of Alzheimer's disease, AP-PS1 and APP23. The XPCT technique enabled high-resolution imaging of brain tissues, distinguishing between different brain structures, such as amyloid deposits and neuronal cells. In addition, the XPCT technique provided detailed information on the distribution and morphology of amyloid deposits in AP-PS1 and APP23 mice putting in evidence the differences between these two models. This work demonstrates the effectiveness of this technique in supporting Alzheimer's studies and evaluating new therapeutic strategies.

physics.med-ph↗

Detection of millihertz quasi-periodic oscillations in the low-mass X-ray binary 4U 1730--22 with NICER

We report the discovery of millihertz quasi-periodic oscillations (mHz QPOs) from the neutron star (NS) low-mass X-ray binary 4U 1730--22 using the Neutron Star Interior Composition Explorer (NICER). After being inactive for almost 50 years, 4U 1730--22 went into outburst twice between June and August 2021, and between February and July 2022. We analyse all the NICER observations of this source, and detect mHz QPOs with a significance > $4σ$ in 35 observations. The QPO frequency of the full data set ranged between ~4.5 and ~8.1 mHz with an average fractional rms amplitude of the order of ~2%. The X-ray colour analysis strongly suggests that 4U 1730--22 was in a soft spectral state during the QPO detections. Our findings are consistent with those reported for other sources where the mHz QPOs have been interpreted as the result of a special mode of He burning on the NS surface called marginally stable nuclear burning (MSNB). We conclude that the mHz QPOs reported in this work are also associated with the MSNB, making 4U 1730--22 the eighth source that shows this phenomenology. We discuss our findings in the context of the heat flux from the NS crust.

astro-ph.HE↗

An ultrafast outflow in the black hole candidate MAXI J1810-222?

The transient X-ray source MAXI J1810-222 was discovered in 2018 and has been active ever since. A long combined radio and X-ray monitoring campaign was performed with ATCA and Swift respectively. It has been proposed that MAXI J1810-222 is a relatively distant black hole X-ray binary, albeit showing a very peculiar outburst behaviour. Here, we report on the spectral study of this source making use of a large sample of NICER observations performed between 2019 February and 2020 September. We detected a strong spectral absorption feature at $\sim$1 keV, which we have characterised with a physical photoionisation model. Via a deep scan of the parameters space, we obtained evidence for a spectral-state dependent outflow, with mildly relativistic speeds. In particular, the soft and intermediate states point to a hot plasma outflowing at 0.05-0.15 $c$. This speeds rule-out thermal winds and, hence, they suggest that such outflows could be radiation pressure or (most likely) magnetically-driven winds. Our results are crucial to test current theoretical models of wind formation in X-ray binaries.

astro-ph.HE↗

On the cyclotron absorption line and evidence of the spectral transition in SMC X-2 during 2022 giant outburst

We report comprehensive spectral and temporal properties of the Be/X-ray binary pulsar SMC X-2 using X-ray observations during the 2015 and 2022 outbursts. The pulse profile of the pulsar is unique and strongly luminosity dependent. It evolves from a broad-humped into a double-peaked profile above luminosity 3$\times$10$^{38}$ ergs s$^{-1}$. The pulse fraction of the pulsar is found to be a linear function of luminosity as well as energy. We also studied the spectral evolution of the source during the latest 2022 outburst with NICER. The observed photon index shows a negative and positive correlation below and above the critical luminosity, respectively, suggesting evidence of spectral transition from the sub-critical to super-critical regime. The broadband spectroscopy of four sets of NuSTAR and XRT/NICER data from both outbursts can be described using a cutoff power-law model with a blackbody component. In addition to the 6.4 keV iron fluorescence line, an absorption-like feature is clearly detected in the spectra. The cyclotron line energy observed during the 2015 outburst is below 29.5 keV, however latest estimates in the 2022 outburst suggest a value of 31.5 keV. Moreover, an increase of 3.4 keV is detected in the cyclotron line energy at equal levels of luminosity observed in 2022 with respect to 2015. The observed cyclotron line energy variation is explored in terms of accretion induced screening mechanism or geometrical variation in line forming region.

astro-ph.HE↗

The SOUL view of IRAS20126+4104. Kinematics and variability of the H$_2$ jet from a massive protostar

We exploit the increased sensitivity of the recently installed AO SOUL at the LBT to obtain new high-spatial-resolution NIR images of the massive young stellar object IRAS20126+4104 and its outflow. We aim to derive the jet proper motions and kinematics, as well as to study its photometric variability by combining the novel performances of SOUL together with previous NIR images. We used both broad-band ($K_{s}$, $K'$) and narrow-band (Br$γ$, H2) observations from a number of NIR cameras (UKIRT/UFTI,SUBARU/CIAO,TNG/NICS,LBT/PISCES,and LBT/LUCI1) to derive maps of the continuum and the H$_2$ emission in the 2.12 $μ$m line. Three sets of images, obtained with AO systems (CIAO,2003; FLAO,2012; SOUL,2020), allowed us to derive the proper motions of a large number of H$_2$ knots along the jet. Photometry from all images was used to study the jet variability. We derived knot proper motions in the range of 1.7-20.3 mas yr$^{-1}$ (i.e. 13-158 km s$^{-1}$ at 1.64 kpc, avg. outflow tangential velocity $\sim$ 80 km s$^{-1}$). The derived knot dynamical age spans a $\sim$ 200-4000 yr interval. A ring-like H$_2$ feature near the protostar location exhibits peculiar kinematics and may represent the outcome of a wide-angle wind impinging on the outflow cavity. Both H$_2$ geometry and velocities agree with those inferred from proper motions of the H$_2$O masers, located at a smaller distance from the protostar. Although the total H$_2$ line emission from the knots does not exhibit time variations at a $\widetilde{>}$ 0.3 mag level, we have found a clear continuum flux variation (radiation scattered by the dust in the cavity opened by the jet) which is anti-correlated between the blue-shifted and red-shifted lobes and may be periodic (with a period of $\sim$ 12-18 yr). We suggest that the continuum variability might be related to inner-disc oscillations which have also caused the jet precession.

astro-ph.SR↗

Spectral analysis of the AMXP IGR J17591-2342 during its 2018 outburst

The Accreting Millisecond X-ray Pulsar IGR J17591-2342 is a LMXB system that went in outburst on August 2018 and it was monitored by the NICER observatory and partially by other facilities. We aim to study how the spectral emission of this source evolved during the outburst, by exploiting the whole X-ray data repository of simultaneous observations. The continuum emission of the combined broad-band spectra is on average well described by an absorbed Comptonisation component scattering black-body-distributed photons peaking at (0.8+/-0.5) keV, by a moderately optically thick corona (tau=2.3+/-0.5) with temperature of (34+/-9) keV. A black-body component with temperature and radial size of (0.8+/-0.2) keV and (3.3+/-1.5) km respectively is required by some of the spectra and suggests that part of the central emission, possibly a fraction of the neutron star surface, is not efficiently scattered by the corona. The continuum at low energies is characterised by significant residuals suggesting the presence of an absorption edge of O VIII and of emission lines of Ne IX ions. Moreover, broad Fe I and Fe XXV K-alpha emission lines are detected at different times of the outburst, suggesting the presence of reflection in the system.

astro-ph.HE↗

The unaltered pulsar: GRO J1750-27, a super-critical X-ray neutron star that does not blink an eye

When accreting X-ray pulsars (XRPs) undergo bright X-ray outbursts, their luminosity-dependent spectral and timing features can be analysed in detail. The XRP GRO J1750-27 recently underwent one of such episodes, during which it was observed with $NuSTAR$ and monitored with $NICER$. Such a data set is rarely available, as it samples the outburst over more than a month at a luminosity that is always exceeding ${\sim}5\times10^{37}\,$erg/s. This value is larger than the typical critical luminosity value, where a radiative shock is formed above the neutron star's surface. Our data analysis of the joint spectra returns a highly ($N_H\sim(5-8)\times10^{22}\,$cm$^{-2}$) absorbed spectrum showing a K$α$ iron line, a soft blackbody component likely originating from the inner edge of the accretion disk, and confirms the discovery of one of the deepest cyclotron lines, at a centroid energy of ${\sim}44\,$keV corresponding to a magnetic field strength of $4.7\times10^{12}\,$G. This value is independently supported by the best-fit physical model for spectral formation in accreting XRPs which, in agreement with recent findings, favours a distance of $14$ kpc and also reflects a bulk-Comptonization dominated accretion flow. Contrary to theoretical expectations and observational evidence from other similar sources, the pulse profiles as observed by $NICER$ through the outburst raise, peak and decay remain remarkably steady. The $NICER$ spectrum, including the iron K$α$ line best-fit parameters, also remain almost unchanged at all probed outburst stages, similar to the pulsed fraction behaviour. We argue that all these phenomena are linked and interpret them as resulting from a saturation effect of the accretion column's emission, which occurs in the high-luminosity regime.

astro-ph.HE↗

MAXI J1957+032: a new accreting millisecond X-ray pulsar in an ultra-compact binary

The detection of coherent X-ray pulsations at ~314 Hz (3.2 ms) classifies MAXI J1957+032 as a fast-rotating, accreting neutron star. We present the temporal and spectral analysis performed using NICER observations collected during the latest outburst of the source. Doppler modulation of the X-ray pulsation revealed the ultra-compact nature of the binary system characterised by an orbital period of ~1 hour and a projected semi-major axis of 14 lt-ms. The neutron star binary mass function suggests a minimum donor mass of 1.7e-2 Msun, assuming a neutron star mass of 1.4 Msun and a binary inclination angle lower than 60 degrees. This assumption is supported by the lack of eclipses or dips in the X-ray light curve of the source. We characterised the 0.5-10 keV energy spectrum of the source in outburst as the superposition of a relatively cold black-body-like thermal emission compatible with the emission from the neutron star surface and a Comptonisation component with photon index consistent with a typical hard state. We did not find evidence for iron K-alpha lines or reflection components.

astro-ph.HE↗

Outflows and spectral evolution in the eclipsing AMXP SWIFT J1749.4-2807 with NICER, XMM-Newton and NuSTAR

The neutron star low-mass X-ray binary SWIFT J1749.4-2807 is the only known eclipsing accreting millisecond X-ray pulsar. In this manuscript we perform a spectral characterization of the system throughout its 2021, two-week-long outburst, analyzing 11 NICER observations and quasi-simultaneous XMM-Newton and NuSTAR single observations at the outburst peak. The broadband spectrum is well-modeled with a black body component with a temperature of $\sim$0.6 keV, most likely consistent with a hot spot on the neutron star surface, and a Comptonisation spectrum with power-law index $Γ\sim 1.9$, arising from a hot corona at $\sim$12 keV. No direct emission from the disc was found, possibly due to it being too cool. A high truncation radius for the disc, i.e., at $\sim$20--30 R$_{G}$ , was obtained from the analysis of the broadened profile of the Fe line in the reflection component. The significant detection of a blue-shifted Fe XXVI absorption line at $\sim$7 keV indicates weakly relativistic X-ray disc winds, which are typically absent in the hard state of X-ray binaries. By comparing the low flux observed during the outburst and the one expected in a conservative mass-transfer, we conclude that mass-transfer in the system is highly non-conservative, as also suggested by the wind detection. Finally, using the Nicer spectra alone, we followed the system while it was fading to quiescence. During the outburst decay, as the spectral shape hardened, the hot spot on the neutron star surface cooled down and shrank, a trend which could be consistent with the pure power-law spectrum observed during quiescence.

astro-ph.HE↗

On the peculiar long-term orbital evolution of the eclipsing accreting millisecond X-ray pulsar SWIFT J1749.4-2807

We present the pulsar timing analysis of the accreting millisecond X-ray pulsar SWIFT J1749.4-2807 monitored by NICER and XMM-Newton during its latest outburst after almost eleven years of quiescence. From the coherent timing analysis of the pulse profiles, we updated the orbital ephemerides of the system. Large phase jumps of the fundamental frequency phase of the signal are visible during the outburst, consistent with what was observed during the previous outburst. Moreover, we report on the marginally significant evidence for non-zero eccentricity ($e\simeq 4\times 10^{-5}$) obtained independently from the analysis of both the 2021 and 2010 outbursts and we discuss possible compatible scenarios. Long-term orbital evolution of SWIFT J1749.4-2807 suggests a fast expansion of both the NS projected semi-major axis $(x)$, and the orbital period $(P_{\rm orb})$, at a rate of $\dot{x}\simeq 2.6\times 10^{-13}\,\text{lt-s}\,\text{s}^{-1}$ and $\dot{P}_{\rm orb}\simeq 4 \times 10^{-10}\,\text{s}\,\text{s}^{-1}$, respectively. SWIFT J1749.4-2807 is the only accreting millisecond X-ray pulsar, so far, from which the orbital period derivative has been directly measured from appreciable changes on the observed orbital period. Finally, no significant secular deceleration of the spin frequency of the compact object is detected, which allowed us to set a constraint on the magnetic field strength at the polar caps of $B_{PC}<1.3\times 10^{8}~\text{G}$, in line with typical values reported for AMXPs.

astro-ph.HE↗

X-ray Phase Contrast Tomography to assess the sequential evolution of multi-organ damage in an animal model of multiple sclerosis

We use X-ray phase-contrast tomography (XPCT) in a multi-organ approach to identify early imaging markers predictive of multiple sclerosis (MS) in EAE animal model. As the majority of neurodegenerative diseases, MS is characterized by a progressive accumulation of biological deficits across different organs and systems. A simultaneous imaging of different disease-relevant networks and a multiscale imaging, ranging from the single cell through to the organ as a whole, are required to provide complete reliable information. XPCT offers the unprecedented possibility to investigate structural and cellular alterations at brain, gut, and eye levels in a multiscale approach. The comparison between naive mice and EAE-affected mice sacrificed at different time points and the correlation of the data from different organs and different time points, unveils the identification of early changes in organs possible predictive of the disease.

physics.med-ph↗

Spectral analysis of the low-mass X-ray pulsar 4U 1822-371: Reflection component in a high-inclination system

The X-ray source 4U 1822-371 is an eclipsing low-mass X-ray binary and X-ray pulsar, hosting a NS that shows periodic pulsations in the X-ray band. The inclination angle of the system is so high that in principle, it should be hard to observe both the direct thermal emission of the central object and the reflection component of the spectrum because they are hidden by the outer edge of the accretion disc. Assuming that the source accretes at the Eddington limit, we analysed non-simultaneous XMM-Newton and NuSTAR observations and studied the average broadband spectrum, with the aim to investigate the presence of a reflection component. No such component has been observed before in a high-inclination source such as 4U 1822-371. We modelled the spectral emission of the source using two different reflection models, Diskline plus Pexriv and the self-consistent model RfxConv. In our analysis, we find significant evidence of a reflection component in the spectrum, in addition to two lines associated with neutral or mildly ionised iron. The continuum spectrum is well fitted by a saturated Comptonisation model and a thermal black-body component emitted by the accretion disc at a lower temperature. We updated the ephemeris, adding two new eclipse times to the most recent ephemeris reported in literature. In our proposed scenario, the source is accreting at the Eddington limit with an intrinsic luminosity of $10^{38}$ erg/s, while the observed luminosity is two orders of magnitude lower. Despite the high inclination, we find that a reflection component is required to fit residuals at the Fe line range and the hard excess observed in the spectrum. The best-fit value of the inner disc radius is still uncertain and model dependent. More observations are therefore needed to confirm these results, which can give important information on this enigmatic and peculiar source.

astro-ph.HE↗

Fe K$α$ and Fe K$β$ line detection in the NuSTAR spectrum of the ultra-bright Z-source Scorpius X-1

Low-mass X-ray binaries hosting a low-magnetised neutron star, which accretes matter via Roche-lobe overflow, are generally grouped in two classes, named Atoll and Z sources after the path described in their X-ray colour-colour diagrams. Scorpius X-1 is the brightest persistent low-mass X-ray binary known so far, and it is the prototype of the Z sources. We analysed the first NuSTAR observation of this source to study its spectral emission exploiting the high statistics data collected by this satellite. Examining the colour-colour diagram, the source was probably observed during the lower normal and flaring branches of its Z-track. We separated the data from the two branches in order to investigate the evolution of the source along the track. We fitted the 3-60 keV NuSTAR spectra using the same models for both the branches. We adopted two description for the continuum: in the first case we used a blackbody and a thermal Comptonisation with seed photons originating in the accretion disc; in the second one, we adopted a disc-blackbody and a Comptonisation with a blackbody-shaped spectrum of the incoming seed photons. A power-law fitting the high energy emission above 20 keV was also required in both cases. The two models provide the same physical scenario for the source in both the branches: a blackbody temperature between 0.8 and 1.5 keV, a disc-blackbody with temperature between 0.4 and 0.6 keV, and an optically thick Comptonising corona with optical depth between 6 and 10 and temperature about 3 keV. Furthermore, two lines related to the K$α$ and K$β$ transitions of the He-like Fe XXV ions were detected at 6.6 keV and 7.8 keV, respectively. A hard tail modelled by a power law with a photon index between 2 and 3 was also required for both the models.

astro-ph.HE↗

Physical conditions in the warped accretion disk of a massive star. 349 GHz ALMA observations of G023.01$-$00.41

Young massive stars warm up the large amount of gas and dust which condenses in their vicinity, exciting a forest of lines from different molecular species. Their line brightness is a diagnostic tool of the gas physical conditions locally, which we use to set constraints on the environment where massive stars form. We made use of the Atacama Large Millimeter/submillimeter Array at frequencies near 349 GHz, with an angular resolution of $0.1''$, to observe the methyl cyanide (CH$_3$CN) emission which arises from the accretion disk of a young massive star. We sample the disk midplane with twelve distinct beams, where we get an independent measure of the gas (and dust) physical conditions. The accretion disk extends above the midplane showing a double-armed spiral morphology projected onto the plane of the sky, which we sample with ten additional beams: along these apparent spiral features, gas undergoes velocity gradients of about $\rm 1 km s^{-1}$ per 2000 au. The gas temperature (T) rises symmetrically along each side of the disk, from about 98 K at 3000 au to 289 K at 250 au, following a power law with radius, R$^{-0.43}$. The CH$_3$CN column density (N) increases from $\rm 9.2\times10^{15} cm^{-2}$ to $\rm 8.7\times10^{17} cm^{-2}$ at the same radii, following a power law with radius, R$^{-1.8}$. In the framework of a circular gaseous disk observed approximately edge-on, we infer an H$_2$ volume density in excess of $\rm 4.8\times10^9 cm^{-3}$ at a distance of 250 au from the star. We study the disk stability against fragmentation following the methodology by Kratter et al. (2010), appropriate under rapid accretion, and we show that the disk is marginally prone to fragmentation along its whole extent.

astro-ph.GA↗

Time Domain Astronomy with the THESEUS Satellite

THESEUS is a medium size space mission of the European Space Agency, currently under evaluation for a possible launch in 2032. Its main objectives are to investigate the early Universe through the observation of gamma-ray bursts and to study the gravitational waves electromagnetic counterparts and neutrino events. On the other hand, its instruments, which include a wide field of view X-ray (0.3-5 keV) telescope based on lobster-eye focusing optics and a gamma-ray spectrometer with imaging capabilities in the 2-150 keV range, are also ideal for carrying out unprecedented studies in time domain astrophysics. In addition, the presence onboard of a 70 cm near infrared telescope will allow simultaneous multi-wavelegth studies. Here we present the THESEUS capabilities for studying the time variability of different classes of sources in parallel to, and without affecting, the gamma-ray bursts hunt.

astro-ph.IM↗

Optical and ultraviolet pulsed emission from an accreting millisecond pulsar

Millisecond spinning, low magnetic field neutron stars are believed to attain their fast rotation in a 0.1-1 Gyr-long phase during which they accrete matter endowed with angular momentum from a low-mass companion star. Despite extensive searches, coherent periodicities originating from accreting neutron star magnetospheres have been detected only at X-ray energies and in ~10% of the presently known systems. Here we report the detection of optical and ultraviolet coherent pulsations at the X-ray period of the transient low mass X-ray binary system SAX J1808.4-3658, during an accretion outburst that occurred in August 2019. At the time of the observations, the pulsar was surrounded by an accretion disc, displayed X-ray pulsations and its luminosity was consistent with magnetically funneled accretion onto the neutron star. Current accretion models fail to account for the luminosity of both optical and ultraviolet pulsations; these are instead more likely driven by synchro-curvature radiation in the pulsar magnetosphere or just outside of it. This interpretation would imply that particle acceleration can take place even when mass accretion is going on, and opens up new perspectives in the study of coherent optical/UV pulsations from fast spinning accreting neutron stars in low-mass X-ray binary systems.

astro-ph.HE↗

Multi-scale view of star formation in IRAS 21078+5211: From clump fragmentation to disk wind

In the massive star-forming region IRAS 21078+5211, a highly fragmented cluster (0.1~pc in size) of molecular cores is observed, located at the density peak of an elongated (1~pc in size) molecular cloud. A small (1~km/s per 0.1~pc) LSR velocity (Vlsr) gradient is detected across the axis of the molecular cloud. Assuming we are observing a mass flow from the harboring cloud to the cluster, we derive a mass infall rate of about 10^{-4}~M_{sun}~yr^{-1}. The most massive cores (labeled 1, 2, and 3) are found at the center of the cluster, and these are the only ones that present a signature of protostellar activity in terms of emission from high-excitation molecular lines or a molecular outflow. We reveal an extended (size about 0.1~pc), bipolar collimated molecular outflow emerging from core 1. We believe this is powered by a (previously discovered) compact (size <= 1000~au) radio jet, ejected by a YSO embedded in core 1 (named YSO-1), since the molecular outflow and the radio jet are almost parallel and have a comparable momentum rate. By means of high-excitation lines, we find a large (14~km/s over 500~au) Vlsr gradient at the position of YSO-1, oriented approximately perpendicular to the radio jet. Assuming this is an edge-on, rotating disk and fitting a Keplerian rotation pattern, we determine the YSO-1 mass to be 5.6+/-2.0~M_{sun}. The water masers (previously observed with VLBI) emerge within 100-300~au from YSO-1 and are unique tracers of the jet kinematics. Their three-dimensional (3D) velocity pattern reveals that the gas flows along, and rotates about, the jet axis. We show that the 3D maser velocities are fully consistent with the magneto-centrifugal disk-wind models predicting a cylindrical rotating jet. Under this hypothesis, we determine the jet radius to be about 16~au and the corresponding launching radius and terminal velocity to be about 2.2~au and 200~km/s, respectively.

astro-ph.GA↗

GrailQuest & HERMES: Hunting for Gravitational Wave Electromagnetic Counterparts and Probing Space-Time Quantum Foam

GrailQuest (Gamma-ray Astronomy International Laboratory for Quantum Exploration of Space-Time) is an ambitious astrophysical mission concept that uses a fleet of small satellites whose main objective is to search for a dispersion law for light propagation in vacuo. Within Quantum Gravity theories, different models for space-time quantization predict relative discrepancies of the speed of photons w.r.t. the speed of light that depend on the ratio of the photon energy to the Planck energy. This ratio is as small as 1E-23 for photons in the gamma-ray band (100 keV). Therefore, to detect this effect, light must propagate over enormous distances and the experiment must have extraordinary sensitivity. Gamma-Ray Bursts, occurring at cosmological distances, could be used to detect this tiny signature of space-time granularity. This can be obtained by coherently combine a huge number of small instruments distributed in space to act as a single detector of unprecedented effective area. This is the first example of high-energy distributed astronomy: a new concept of modular observatory of huge overall collecting area consisting in a fleet of small satellites in low orbits, with sub-microsecond time resolution and wide energy band (keV-MeV). The enormous number of collected photons will allow to effectively search these energy dependent delays. Moreover, GrailQuest will allow to perform temporal triangulation of impulsive events with arc-second positional accuracies: an extraordinary sensitive X-ray/Gamma all-sky monitor crucial for hunting the elusive electromagnetic counterparts of Gravitational Waves, that will play a paramount role in the future of Multi-messenger Astronomy. A pathfinder of GrailQuest is already under development through the HERMES (High Energy Rapid Modular Ensemble of Satellites) project: a fleet of six 3U cube-sats to be launched by the end of 2022.

astro-ph.HE↗