arXiv subjects

Aakanksha Naik

Publications and source records attributed to Aakanksha Naik.

31 records · Page 2Linked to original sources

arXiv2024

NLP for Maternal Healthcare: Perspectives and Guiding Principles in the Age of LLMs

Ethical frameworks for the use of natural language processing (NLP) are urgently needed to shape how large language models (LLMs) and similar tools are used for healthcare applications. Healthcare faces existing challenges including the balance of power in clinician-patient relationships, systemic health disparities, historical injustices, and economic constraints. Drawing directly from the voices of those most affected, and focusing on a case study of a specific healthcare setting, we propose a set of guiding principles for the use of NLP in maternal healthcare. We led an interactive session centered on an LLM-based chatbot demonstration during a full-day workshop with 39 participants, and additionally surveyed 30 healthcare workers and 30 birthing people about their values, needs, and perceptions of NLP tools in the context of maternal health. We conducted quantitative and qualitative analyses of the survey results and interactive discussions to consolidate our findings into a set of guiding principles. We propose nine principles for ethical use of NLP for maternal healthcare, grouped into three themes: (i) recognizing contextual significance (ii) holistic measurements, and (iii) who/what is valued. For each principle, we describe its underlying rationale and provide practical advice. This set of principles can provide a methodological pattern for other researchers and serve as a resource to practitioners working on maternal health and other healthcare fields to emphasize the importance of technical nuance, historical context, and inclusive design when developing NLP technologies for clinical use.

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arXiv2023

LongBoX: Evaluating Transformers on Long-Sequence Clinical Tasks

Many large language models (LLMs) for medicine have largely been evaluated on short texts, and their ability to handle longer sequences such as a complete electronic health record (EHR) has not been systematically explored. Assessing these models on long sequences is crucial since prior work in the general domain has demonstrated performance degradation of LLMs on longer texts. Motivated by this, we introduce LongBoX, a collection of seven medical datasets in text-to-text format, designed to investigate model performance on long sequences. Preliminary experiments reveal that both medical LLMs (e.g., BioGPT) and strong general domain LLMs (e.g., FLAN-T5) struggle on this benchmark. We further evaluate two techniques designed for long-sequence handling: (i) local-global attention, and (ii) Fusion-in-Decoder (FiD). Our results demonstrate mixed results with long-sequence handling - while scores on some datasets increase, there is substantial room for improvement. We hope that LongBoX facilitates the development of more effective long-sequence techniques for the medical domain. Data and source code are available at https://github.com/Mihir3009/LongBoX.

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arXiv2023

SynerGPT: In-Context Learning for Personalized Drug Synergy Prediction and Drug Design

Predicting synergistic drug combinations can help accelerate discovery of cancer treatments, particularly therapies personalized to a patient's specific tumor via biopsied cells. In this paper, we propose a novel setting and models for in-context drug synergy learning. We are given a small "personalized dataset" of 10-20 drug synergy relationships in the context of specific cancer cell targets. Our goal is to predict additional drug synergy relationships in that context. Inspired by recent work that pre-trains a GPT language model (LM) to "in-context learn" common function classes, we devise novel pre-training schemes that enable a GPT model to in-context learn "drug synergy functions". Our model -- which does not use any textual corpora, molecular fingerprints, protein interaction or any other domain-specific knowledge -- is able to achieve competitive results. We further integrate our in-context approach with a genetic algorithm to optimize model prompts and select synergy candidates to test after conducting a patient biopsy. Finally, we explore a novel task of inverse drug design which can potentially enable the design of drugs that synergize specifically to target a given patient's "personalized dataset". Our findings can potentially have an important impact on precision cancer medicine, and also raise intriguing questions on non-textual pre-training for LMs.

cs.AI↗

arXiv2023

S2abEL: A Dataset for Entity Linking from Scientific Tables

Entity linking (EL) is the task of linking a textual mention to its corresponding entry in a knowledge base, and is critical for many knowledge-intensive NLP applications. When applied to tables in scientific papers, EL is a step toward large-scale scientific knowledge bases that could enable advanced scientific question answering and analytics. We present the first dataset for EL in scientific tables. EL for scientific tables is especially challenging because scientific knowledge bases can be very incomplete, and disambiguating table mentions typically requires understanding the papers's tet in addition to the table. Our dataset, S2abEL, focuses on EL in machine learning results tables and includes hand-labeled cell types, attributed sources, and entity links from the PaperswithCode taxonomy for 8,429 cells from 732 tables. We introduce a neural baseline method designed for EL on scientific tables containing many out-of-knowledge-base mentions, and show that it significantly outperforms a state-of-the-art generic table EL method. The best baselines fall below human performance, and our analysis highlights avenues for improvement.

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arXiv2023

The Semantic Reader Project: Augmenting Scholarly Documents through AI-Powered Interactive Reading Interfaces

Scholarly publications are key to the transfer of knowledge from scholars to others. However, research papers are information-dense, and as the volume of the scientific literature grows, the need for new technology to support the reading process grows. In contrast to the process of finding papers, which has been transformed by Internet technology, the experience of reading research papers has changed little in decades. The PDF format for sharing research papers is widely used due to its portability, but it has significant downsides including: static content, poor accessibility for low-vision readers, and difficulty reading on mobile devices. This paper explores the question "Can recent advances in AI and HCI power intelligent, interactive, and accessible reading interfaces -- even for legacy PDFs?" We describe the Semantic Reader Project, a collaborative effort across multiple institutions to explore automatic creation of dynamic reading interfaces for research papers. Through this project, we've developed ten research prototype interfaces and conducted usability studies with more than 300 participants and real-world users showing improved reading experiences for scholars. We've also released a production reading interface for research papers that will incorporate the best features as they mature. We structure this paper around challenges scholars and the public face when reading research papers -- Discovery, Efficiency, Comprehension, Synthesis, and Accessibility -- and present an overview of our progress and remaining open challenges.

cs.HC↗

arXiv2023

Relatedly: Scaffolding Literature Reviews with Existing Related Work Sections

Scholars who want to research a scientific topic must take time to read, extract meaning, and identify connections across many papers. As scientific literature grows, this becomes increasingly challenging. Meanwhile, authors summarize prior research in papers' related work sections, though this is scoped to support a single paper. A formative study found that while reading multiple related work paragraphs helps overview a topic, it is hard to navigate overlapping and diverging references and research foci. In this work, we design a system, Relatedly, that scaffolds exploring and reading multiple related work paragraphs on a topic, with features including dynamic re-ranking and highlighting to spotlight unexplored dissimilar information, auto-generated descriptive paragraph headings, and low-lighting of redundant information. From a within-subjects user study (n=15), we found that scholars generate more coherent, insightful, and comprehensive topic outlines using Relatedly compared to a baseline paper list.

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arXiv2022

Literature-Augmented Clinical Outcome Prediction

We present BEEP (Biomedical Evidence-Enhanced Predictions), a novel approach for clinical outcome prediction that retrieves patient-specific medical literature and incorporates it into predictive models. Based on each individual patient's clinical notes, we train language models (LMs) to find relevant papers and fuse them with information from notes to predict outcomes such as in-hospital mortality. We develop methods to retrieve literature based on noisy, information-dense patient notes, and to augment existing outcome prediction models with retrieved papers in a manner that maximizes predictive accuracy. Our approach boosts predictive performance on three important clinical tasks in comparison to strong recent LM baselines, increasing F1 by up to 5 points and precision@Top-K by a large margin of over 25%.

cs.CL↗

arXiv2022

Adapting to the Long Tail: A Meta-Analysis of Transfer Learning Research for Language Understanding Tasks

Natural language understanding (NLU) has made massive progress driven by large benchmarks, but benchmarks often leave a long tail of infrequent phenomena underrepresented. We reflect on the question: have transfer learning methods sufficiently addressed the poor performance of benchmark-trained models on the long tail? We conceptualize the long tail using macro-level dimensions (e.g., underrepresented genres, topics, etc.), and perform a qualitative meta-analysis of 100 representative papers on transfer learning research for NLU. Our analysis asks three questions: (i) Which long tail dimensions do transfer learning studies target? (ii) Which properties of adaptation methods help improve performance on the long tail? (iii) Which methodological gaps have greatest negative impact on long tail performance? Our answers highlight major avenues for future research in transfer learning for the long tail. Lastly, using our meta-analysis framework, we perform a case study comparing the performance of various adaptation methods on clinical narratives, which provides interesting insights that may enable us to make progress along these future avenues.

cs.CL↗

arXiv2021

STAGE: Tool for Automated Extraction of Semantic Time Cues to Enrich Neural Temporal Ordering Models

Despite achieving state-of-the-art accuracy on temporal ordering of events, neural models showcase significant gaps in performance. Our work seeks to fill one of these gaps by leveraging an under-explored dimension of textual semantics: rich semantic information provided by explicit textual time cues. We develop STAGE, a system that consists of a novel temporal framework and a parser that can automatically extract time cues and convert them into representations suitable for integration with neural models. We demonstrate the utility of extracted cues by integrating them with an event ordering model using a joint BiLSTM and ILP constraint architecture. We outline the functionality of the 3-part STAGE processing approach, and show two methods of integrating its representations with the BiLSTM-ILP model: (i) incorporating semantic cues as additional features, and (ii) generating new constraints from semantic cues to be enforced in the ILP. We demonstrate promising results on two event ordering datasets, and highlight important issues in semantic cue representation and integration for future research.

cs.CL↗

arXiv2020

Adapting Event Extractors to Medical Data: Bridging the Covariate Shift

We tackle the task of adapting event extractors to new domains without labeled data, by aligning the marginal distributions of source and target domains. As a testbed, we create two new event extraction datasets using English texts from two medical domains: (i) clinical notes, and (ii) doctor-patient conversations. We test the efficacy of three marginal alignment techniques: (i) adversarial domain adaptation (ADA), (ii) domain adaptive fine-tuning (DAFT), and (iii) a novel instance weighting technique based on language model likelihood scores (LIW). LIW and DAFT improve over a no-transfer BERT baseline on both domains, but ADA only improves on clinical notes. Deeper analysis of performance under different types of shifts (e.g., lexical shift, semantic shift) reveals interesting variations among models. Our best-performing models reach F1 scores of 70.0 and 72.9 on notes and conversations respectively, using no labeled data from target domains.

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arXiv2020

Towards Open Domain Event Trigger Identification using Adversarial Domain Adaptation

We tackle the task of building supervised event trigger identification models which can generalize better across domains. Our work leverages the adversarial domain adaptation (ADA) framework to introduce domain-invariance. ADA uses adversarial training to construct representations that are predictive for trigger identification, but not predictive of the example's domain. It requires no labeled data from the target domain, making it completely unsupervised. Experiments with two domains (English literature and news) show that ADA leads to an average F1 score improvement of 3.9 on out-of-domain data. Our best performing model (BERT-A) reaches 44-49 F1 across both domains, using no labeled target data. Preliminary experiments reveal that finetuning on 1% labeled data, followed by self-training leads to substantial improvement, reaching 51.5 and 67.2 F1 on literature and news respectively.

cs.CL↗

arXiv2019

EQUATE: A Benchmark Evaluation Framework for Quantitative Reasoning in Natural Language Inference

Quantitative reasoning is a higher-order reasoning skill that any intelligent natural language understanding system can reasonably be expected to handle. We present EQUATE (Evaluating Quantitative Understanding Aptitude in Textual Entailment), a new framework for quantitative reasoning in textual entailment. We benchmark the performance of 9 published NLI models on EQUATE, and find that on average, state-of-the-art methods do not achieve an absolute improvement over a majority-class baseline, suggesting that they do not implicitly learn to reason with quantities. We establish a new baseline Q-REAS that manipulates quantities symbolically. In comparison to the best performing NLI model, it achieves success on numerical reasoning tests (+24.2%), but has limited verbal reasoning capabilities (-8.1%). We hope our evaluation framework will support the development of models of quantitative reasoning in language understanding.

cs.CL↗

arXiv2018

Stress Test Evaluation for Natural Language Inference

Natural language inference (NLI) is the task of determining if a natural language hypothesis can be inferred from a given premise in a justifiable manner. NLI was proposed as a benchmark task for natural language understanding. Existing models perform well at standard datasets for NLI, achieving impressive results across different genres of text. However, the extent to which these models understand the semantic content of sentences is unclear. In this work, we propose an evaluation methodology consisting of automatically constructed "stress tests" that allow us to examine whether systems have the ability to make real inferential decisions. Our evaluation of six sentence-encoder models on these stress tests reveals strengths and weaknesses of these models with respect to challenging linguistic phenomena, and suggests important directions for future work in this area.

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