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Aaqib Saeed

Publications and source records attributed to Aaqib Saeed.

At least 37 records · Page 2Linked to original sources

Electrocardiogram-Language Model for Few-Shot Question Answering with Meta Learning

Electrocardiogram (ECG) interpretation requires specialized expertise, often involving synthesizing insights from ECG signals with complex clinical queries posed in natural language. The scarcity of labeled ECG data coupled with the diverse nature of clinical inquiries presents a significant challenge for developing robust and adaptable ECG diagnostic systems. This work introduces a novel multimodal meta-learning method for few-shot ECG question answering, addressing the challenge of limited labeled data while leveraging the rich knowledge encoded within large language models (LLMs). Our LLM-agnostic approach integrates a pre-trained ECG encoder with a frozen LLM (e.g., LLaMA and Gemma) via a trainable fusion module, enabling the language model to reason about ECG data and generate clinically meaningful answers. Extensive experiments demonstrate superior generalization to unseen diagnostic tasks compared to supervised baselines, achieving notable performance even with limited ECG leads. For instance, in a 5-way 5-shot setting, our method using LLaMA-3.1-8B achieves an accuracy of 84.6%, 77.3%, and 69.6% on single verify, choose and query question types, respectively. These results highlight the potential of our method to enhance clinical ECG interpretation by combining signal processing with the nuanced language understanding capabilities of LLMs, particularly in data-constrained scenarios.

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Boosting Masked ECG-Text Auto-Encoders as Discriminative Learners

The accurate interpretation of Electrocardiogram (ECG) signals is pivotal for diagnosing cardiovascular diseases. Integrating ECG signals with accompanying textual reports further holds immense potential to enhance clinical diagnostics by combining physiological data and qualitative insights. However, this integration faces significant challenges due to inherent modality disparities and the scarcity of labeled data for robust cross-modal learning. To address these obstacles, we propose D-BETA, a novel framework that pre-trains ECG and text data using a contrastive masked auto-encoder architecture. D-BETA uniquely combines the strengths of generative with boosted discriminative capabilities to achieve robust cross-modal representations. This is accomplished through masked modality modeling, specialized loss functions, and an improved negative sampling strategy tailored for cross-modal alignment. Extensive experiments on five public datasets across diverse downstream tasks demonstrate that D-BETA significantly outperforms existing methods, achieving an average AUC improvement of 15% in linear probing with only one percent of training data and 2% in zero-shot performance without requiring training data over state-of-the-art models. These results highlight the effectiveness of D-BETA, underscoring its potential to advance automated clinical diagnostics through multi-modal representations. Our sample code and checkpoint are made available at https://github.com/manhph2211/D-BETA.

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Q-Heart: ECG Question Answering via Knowledge-Informed Multimodal LLMs

Electrocardiography (ECG) offers critical cardiovascular insights, such as identifying arrhythmias and myocardial ischemia, but enabling automated systems to answer complex clinical questions directly from ECG signals (ECG-QA) remains a significant challenge. Current approaches often lack robust multimodal reasoning capabilities or rely on generic architectures ill-suited for the nuances of physiological signals. We introduce Q-Heart, a novel multimodal framework designed to bridge this gap. Q-Heart leverages a powerful, adapted ECG encoder and integrates its representations with textual information via a specialized ECG-aware transformer-based mapping layer. Furthermore, Q-Heart leverages dynamic prompting and retrieval of relevant historical clinical reports to guide tuning the language model toward knowledge-aware ECG reasoning. Extensive evaluations on the benchmark ECG-QA dataset show Q-Heart achieves state-of-the-art performance, outperforming existing methods by a 4% improvement in exact match accuracy. Our work demonstrates the effectiveness of combining domain-specific architectural adaptations with knowledge-augmented LLM instruction tuning for complex physiological ECG analysis, paving the way for more capable and potentially interpretable clinical patient care systems.

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Reliable Physiological Monitoring on the Wrist Using Generative Deep Learning to Address Poor Skin-Sensor Contact

Photoplethysmography (PPG) is a widely adopted, non-invasive technique for monitoring cardiovascular health and physiological parameters in both consumer and clinical settings. While motion artifacts in dynamic environments have been extensively studied, suboptimal skin-sensor contact in sedentary conditions - a critical yet underexplored issue - can distort PPG waveform morphology, leading to the loss or misalignment of key features and compromising sensing accuracy. In this work, we propose CP-PPG, a novel framework that transforms Contact Pressure-distorted PPG signals into high-fidelity waveforms with ideal morphology. CP-PPG integrates a custom data collection protocol, a carefully designed signal processing pipeline, and a novel deep adversarial model trained with a custom PPG-aware loss function. We validated CP-PPG through comprehensive evaluations, including 1) morphology transformation performance on our self-collected dataset, 2) downstream physiological monitoring performance on public datasets, and 3) in-the-wild study. Extensive experiments demonstrate substantial and consistent improvements in signal fidelity (Mean Absolute Error: 0.09, 40% improvement over the original signal) as well as downstream performance across all evaluations in Heart Rate (HR), Heart Rate Variability (HRV), Respiration Rate (RR), and Blood Pressure (BP) estimation (on average, 21% improvement in HR; 41-46% in HRV; 6% in RR; and 4-5% in BP). These findings highlight the critical importance of addressing skin-sensor contact issues to enhance the reliability and effectiveness of PPG-based physiological monitoring. CP-PPG thus holds significant potential to improve the accuracy of wearable health technologies in clinical and consumer applications.

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PedSleepMAE: Generative Model for Multimodal Pediatric Sleep Signals

Pediatric sleep is an important but often overlooked area in health informatics. We present PedSleepMAE, a generative model that fully leverages multimodal pediatric sleep signals including multichannel EEGs, respiratory signals, EOGs and EMG. This masked autoencoder-based model performs comparably to supervised learning models in sleep scoring and in the detection of apnea, hypopnea, EEG arousal and oxygen desaturation. Its embeddings are also shown to capture subtle differences in sleep signals coming from a rare genetic disorder. Furthermore, PedSleepMAE generates realistic signals that can be used for sleep segment retrieval, outlier detection, and missing channel imputation. This is the first general-purpose generative model trained on multiple types of pediatric sleep signals.

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RespLLM: Unifying Audio and Text with Multimodal LLMs for Generalized Respiratory Health Prediction

The high incidence and mortality rates associated with respiratory diseases underscores the importance of early screening. Machine learning models can automate clinical consultations and auscultation, offering vital support in this area. However, the data involved, spanning demographics, medical history, symptoms, and respiratory audio, are heterogeneous and complex. Existing approaches are insufficient and lack generalizability, as they typically rely on limited training data, basic fusion techniques, and task-specific models. In this paper, we propose RespLLM, a novel multimodal large language model (LLM) framework that unifies text and audio representations for respiratory health prediction. RespLLM leverages the extensive prior knowledge of pretrained LLMs and enables effective audio-text fusion through cross-modal attentions. Instruction tuning is employed to integrate diverse data from multiple sources, ensuring generalizability and versatility of the model. Experiments on five real-world datasets demonstrate that RespLLM outperforms leading baselines by an average of 4.6% on trained tasks, 7.9% on unseen datasets, and facilitates zero-shot predictions for new tasks. Our work lays the foundation for multimodal models that can perceive, listen to, and understand heterogeneous data, paving the way for scalable respiratory health diagnosis.

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Electrocardiogram Report Generation and Question Answering via Retrieval-Augmented Self-Supervised Modeling

Interpreting electrocardiograms (ECGs) and generating comprehensive reports remain challenging tasks in cardiology, often requiring specialized expertise and significant time investment. To address these critical issues, we propose ECG-ReGen, a retrieval-based approach for ECG-to-text report generation and question answering. Our method leverages a self-supervised learning for the ECG encoder, enabling efficient similarity searches and report retrieval. By combining pre-training with dynamic retrieval and Large Language Model (LLM)-based refinement, ECG-ReGen effectively analyzes ECG data and answers related queries, with the potential of improving patient care. Experiments conducted on the PTB-XL and MIMIC-IV-ECG datasets demonstrate superior performance in both in-domain and cross-domain scenarios for report generation. Furthermore, our approach exhibits competitive performance on ECG-QA dataset compared to fully supervised methods when utilizing off-the-shelf LLMs for zero-shot question answering. This approach, effectively combining self-supervised encoder and LLMs, offers a scalable and efficient solution for accurate ECG interpretation, holding significant potential to enhance clinical decision-making.

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Collaboratively Learning Federated Models from Noisy Decentralized Data

Federated learning (FL) has emerged as a prominent method for collaboratively training machine learning models using local data from edge devices, all while keeping data decentralized. However, accounting for the quality of data contributed by local clients remains a critical challenge in FL, as local data are often susceptible to corruption by various forms of noise and perturbations, which compromise the aggregation process and lead to a subpar global model. In this work, we focus on addressing the problem of noisy data in the input space, an under-explored area compared to the label noise. We propose a comprehensive assessment of client input in the gradient space, inspired by the distinct disparity observed between the density of gradient norm distributions of models trained on noisy and clean input data. Based on this observation, we introduce a straightforward yet effective approach to identify clients with low-quality data at the initial stage of FL. Furthermore, we propose a noise-aware FL aggregation method, namely Federated Noise-Sifting (FedNS), which can be used as a plug-in approach in conjunction with widely used FL strategies. Our extensive evaluation on diverse benchmark datasets under different federated settings demonstrates the efficacy of FedNS. Our method effortlessly integrates with existing FL strategies, enhancing the global model's performance by up to 13.68% in IID and 15.85% in non-IID settings when learning from noisy decentralized data.

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Federated Learning with a Single Shared Image

Federated Learning (FL) enables multiple machines to collaboratively train a machine learning model without sharing of private training data. Yet, especially for heterogeneous models, a key bottleneck remains the transfer of knowledge gained from each client model with the server. One popular method, FedDF, uses distillation to tackle this task with the use of a common, shared dataset on which predictions are exchanged. However, in many contexts such a dataset might be difficult to acquire due to privacy and the clients might not allow for storage of a large shared dataset. To this end, in this paper, we introduce a new method that improves this knowledge distillation method to only rely on a single shared image between clients and server. In particular, we propose a novel adaptive dataset pruning algorithm that selects the most informative crops generated from only a single image. With this, we show that federated learning with distillation under a limited shared dataset budget works better by using a single image compared to multiple individual ones. Finally, we extend our approach to allow for training heterogeneous client architectures by incorporating a non-uniform distillation schedule and client-model mirroring on the server side.

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Communication-Efficient Federated Learning through Adaptive Weight Clustering and Server-Side Distillation

Federated Learning (FL) is a promising technique for the collaborative training of deep neural networks across multiple devices while preserving data privacy. Despite its potential benefits, FL is hindered by excessive communication costs due to repeated server-client communication during training. To address this challenge, model compression techniques, such as sparsification and weight clustering are applied, which often require modifying the underlying model aggregation schemes or involve cumbersome hyperparameter tuning, with the latter not only adjusts the model's compression rate but also limits model's potential for continuous improvement over growing data. In this paper, we propose FedCompress, a novel approach that combines dynamic weight clustering and server-side knowledge distillation to reduce communication costs while learning highly generalizable models. Through a comprehensive evaluation on diverse public datasets, we demonstrate the efficacy of our approach compared to baselines in terms of communication costs and inference speed.

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Learning under Label Noise through Few-Shot Human-in-the-Loop Refinement

Wearable technologies enable continuous monitoring of various health metrics, such as physical activity, heart rate, sleep, and stress levels. A key challenge with wearable data is obtaining quality labels. Unlike modalities like video where the videos themselves can be effectively used to label objects or events, wearable data do not contain obvious cues about the physical manifestation of the users and usually require rich metadata. As a result, label noise can become an increasingly thorny issue when labeling such data. In this paper, we propose a novel solution to address noisy label learning, entitled Few-Shot Human-in-the-Loop Refinement (FHLR). Our method initially learns a seed model using weak labels. Next, it fine-tunes the seed model using a handful of expert corrections. Finally, it achieves better generalizability and robustness by merging the seed and fine-tuned models via weighted parameter averaging. We evaluate our approach on four challenging tasks and datasets, and compare it against eight competitive baselines designed to deal with noisy labels. We show that FHLR achieves significantly better performance when learning from noisy labels and achieves state-of-the-art by a large margin, with up to 19% accuracy improvement under symmetric and asymmetric noise. Notably, we find that FHLR is particularly robust to increased label noise, unlike prior works that suffer from severe performance degradation. Our work not only achieves better generalization in high-stakes health sensing benchmarks but also sheds light on how noise affects commonly-used models.

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Distilled Non-Semantic Speech Embeddings with Binary Neural Networks for Low-Resource Devices

This work introduces BRILLsson, a novel binary neural network-based representation learning model for a broad range of non-semantic speech tasks. We train the model with knowledge distillation from a large and real-valued TRILLsson model with only a fraction of the dataset used to train TRILLsson. The resulting BRILLsson models are only 2MB in size with a latency less than 8ms, making them suitable for deployment in low-resource devices such as wearables. We evaluate BRILLsson on eight benchmark tasks (including but not limited to spoken language identification, emotion recognition, health condition diagnosis, and keyword spotting), and demonstrate that our proposed ultra-light and low-latency models perform as well as large-scale models.

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Federated Fine-Tuning of Foundation Models via Probabilistic Masking

Foundation Models (FMs) have revolutionized machine learning with their adaptability and high performance across tasks; yet, their integration into Federated Learning (FL) is challenging due to substantial communication overhead from their extensive parameterization. Current communication-efficient FL strategies, such as gradient compression, reduce bitrates to around $1$ bit-per-parameter (bpp). However, these approaches fail to harness the characteristics of FMs, with their large number of parameters still posing a challenge to communication efficiency, even at these bitrate regimes. In this work, we present DeltaMask, a novel method that efficiently fine-tunes FMs in FL at an ultra-low bitrate, well below 1 bpp. DeltaMask employs stochastic masking to detect highly effective subnetworks within FMs and leverage stochasticity and sparsity in client masks to compress updates into a compact grayscale image using probabilistic filters, deviating from traditional weight training approaches. Our comprehensive evaluations across various datasets and architectures demonstrate DeltaMask efficiently achieves bitrates as low as 0.09 bpp, enhancing communication efficiency while maintaining FMs performance, as measured on 8 datasets and 5 pre-trained models of various network architectures.

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Labeling Chaos to Learning Harmony: Federated Learning with Noisy Labels

Federated Learning (FL) is a distributed machine learning paradigm that enables learning models from decentralized private datasets, where the labeling effort is entrusted to the clients. While most existing FL approaches assume high-quality labels are readily available on users' devices; in reality, label noise can naturally occur in FL and is closely related to clients' characteristics. Due to scarcity of available data and significant label noise variations among clients in FL, existing state-of-the-art centralized approaches exhibit unsatisfactory performance, while prior FL studies rely on excessive on-device computational schemes or additional clean data available on server. Here, we propose FedLN, a framework to deal with label noise across different FL training stages; namely, FL initialization, on-device model training, and server model aggregation, able to accommodate the diverse computational capabilities of devices in a FL system. Specifically, FedLN computes per-client noise-level estimation in a single federated round and improves the models' performance by either correcting or mitigating the effect of noisy samples. Our evaluation on various publicly available vision and audio datasets demonstrate a 22% improvement on average compared to other existing methods for a label noise level of 60%. We further validate the efficiency of FedLN in human-annotated real-world noisy datasets and report a 4.8% increase on average in models' recognition performance, highlighting that~\method~can be useful for improving FL services provided to everyday users.

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Plug-and-Play Multilingual Few-shot Spoken Words Recognition

As technology advances and digital devices become prevalent, seamless human-machine communication is increasingly gaining significance. The growing adoption of mobile, wearable, and other Internet of Things (IoT) devices has changed how we interact with these smart devices, making accurate spoken words recognition a crucial component for effective interaction. However, building robust spoken words detection system that can handle novel keywords remains challenging, especially for low-resource languages with limited training data. Here, we propose PLiX, a multilingual and plug-and-play keyword spotting system that leverages few-shot learning to harness massive real-world data and enable the recognition of unseen spoken words at test-time. Our few-shot deep models are learned with millions of one-second audio clips across 20 languages, achieving state-of-the-art performance while being highly efficient. Extensive evaluations show that PLiX can generalize to novel spoken words given as few as just one support example and performs well on unseen languages out of the box. We release models and inference code to serve as a foundation for future research and voice-enabled user interface development for emerging devices.

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On Out-of-Distribution Detection for Audio with Deep Nearest Neighbors

Out-of-distribution (OOD) detection is concerned with identifying data points that do not belong to the same distribution as the model's training data. For the safe deployment of predictive models in a real-world environment, it is critical to avoid making confident predictions on OOD inputs as it can lead to potentially dangerous consequences. However, OOD detection largely remains an under-explored area in the audio (and speech) domain. This is despite the fact that audio is a central modality for many tasks, such as speaker diarization, automatic speech recognition, and sound event detection. To address this, we propose to leverage feature-space of the model with deep k-nearest neighbors to detect OOD samples. We show that this simple and flexible method effectively detects OOD inputs across a broad category of audio (and speech) datasets. Specifically, it improves the false positive rate (FPR@TPR95) by 17% and the AUROC score by 7% than other prior techniques.

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Active Learning of Non-semantic Speech Tasks with Pretrained Models

Pretraining neural networks with massive unlabeled datasets has become popular as it equips the deep models with a better prior to solve downstream tasks. However, this approach generally assumes that the downstream tasks have access to annotated data of sufficient size. In this work, we propose ALOE, a novel system for improving the data- and label-efficiency of non-semantic speech tasks with active learning. ALOE uses pretrained models in conjunction with active learning to label data incrementally and learn classifiers for downstream tasks, thereby mitigating the need to acquire labeled data beforehand. We demonstrate the effectiveness of ALOE on a wide range of tasks, uncertainty-based acquisition functions, and model architectures. Training a linear classifier on top of a frozen encoder with ALOE is shown to achieve performance similar to several baselines that utilize the entire labeled data.

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