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Aaron Winn

Publications and source records attributed to Aaron Winn.

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Unidirectional flow from continuous broken symmetries

Locally broken symmetries are used across fields to transport matter, particles and information in preferential directions. Beyond local mechanisms, spatially distributed nonlinearities in crystalline media have enabled non-reciprocal transport, a rectification mechanism that operates continuously across scales and frequencies. Here, we show that this concept applies beyond condensed matter, to fluid transport in living organisms and artificial systems. We take the example of the lymphatic vascular system, which transports interstitial fluid in mammals, and demonstrate that distributed leaflets act as continuous broken symmetries. We build an artificial model of a collecting lymphatic and investigate the naturally richer dynamics of unidirectional transport that arises from spatiotemporal excitations. We observe robust and scalable transport for any waveshape and external pressure gradients. We show experimentally and theoretically that the contraction wavelength, directionality, and pulsatility control the flow rate. In particular, we counterintuitively find waveshapes that maximize transport when propagating against the direction of the flow. Overall, our findings advance the understanding of unidirectional fluid transport in living systems and beyond, and reveal how coupling nonlinearities with spatiotemporal excitations can tune such transport across fields.

cond-mat.soft

The Geometry of Contraction-Induced Flows

Peristalsis is the driving mechanism behind a broad array of biological and engineered flows. In peristaltic pumping, a wave-like contraction of the tube wall produces local changes in volume which induce flow. Net flow arises due to geometric nonlinearities in the momentum equation, which must be properly captured to compute the flow accurately. While most previous models focus on radius-imposed peristalsis, they often neglect longitudinal length changes - a natural consequence of radial contraction in elastic materials. In this paper, to capture a more accurate picture of peristaltic pumping, we calculate the flow in an elastic vessel undergoing contractions in the transverse and longitudinal directions simultaneously, keeping the geometric nonlinearities arising in the strain. A careful analysis requires us to study our fluid using the Lagrangian coordinates of the elastic tube. We perform analytic calculations of the flow characteristics by studying the fluid inside a fixed boundary with time-dependent metric. This mathematical manipulation works even for large-amplitude contractions, as we confirm by comparing our analytical results to COMSOL simulations. We demonstrate that transverse and longitudinal contractions induce instantaneous flows at the same order in wall strain, but in opposite directions. We investigate the influence of the wall's Poisson ratio on the flow profile. Incompressible walls suppress flow by minimizing local volume changes, whereas auxetic walls enhance flow. For radius-imposed peristaltic waves, wall incompressibility reduces both reflux and particle trapping. In contrast, length-imposed waves typically generate backflow, although trapping can still occur at large amplitudes for some Poisson ratios. These results yield a more complete description of peristalsis in elastic media and offer a framework for studying contraction-induced flows more broadly.

physics.flu-dyn

From localized to well-mixed: How commuter interactions shape disease spread

Interactions between commuting individuals can lead to large-scale spreading of rumors, ideas, or disease, even though the commuters have no net displacement. The emergent dynamics depend crucially on the commuting distribution of a population, that is how the probability to travel to a destination decays with distance from home. Applying this idea to epidemics, we will demonstrate the qualitatively different infection dynamics emerging from populations with different commuting distributions. If the commuting distribution is exponentially localized, we recover a reaction-diffusion system and observe Fisher waves traveling at a speed proportional to the characteristic commuting distance. If the commuting distribution has a long tail, then no finite-velocity waves can form, but we show that, in some regimes, there is nontrivial spatial dependence that the well-mixed approximation neglects. We discuss how, in all cases, an initial dispersal-dominated regime can allow the disease to go undetected for a finite amount of time before exponential growth takes over. This "offset time" is a quantity of huge importance for epidemic surveillance and yet largely ignored in the literature.

q-bio.PE

Operating Principles of Peristaltic Pumping through a Dense Array of Valves

Immersed nonlinear elements are prevalent in biological systems that require a preferential flow direction, such as the venous and the lymphatic system. We investigate here a certain class of models where the fluid is driven by peristaltic pumping and the nonlinear elements are ideal valves that completely suppress backflow. This highly nonlinear system produces discontinuous solutions that are difficult to study. We show that as the density of valves increases, the pressure and flow are well-approximated by a continuum of valves which can be analytically treated, and we demonstrate through numeric simulation that the approximation works well even for intermediate valve densities. We find that the induced flow is linear in the peristaltic amplitude for small peristaltic forces and, in the case of sinusoidal peristalsis, is independent of pumping direction. Despite the continuum approximation used, the physical valve density is accounted for by modifying the resistance of the fluid appropriately. The suppression of backflow causes a net benefit in adding valves when the valve density is low, but once the density is high enough, valves predominately suppress forward flow, suggesting there is an optimum number of valves per wavelength. The continuum model for peristaltic pumping through an array of valves presented in this work can eventually provide insights about the design and operating principles of complex flow networks with a broad class of nonlinear elements.

physics.flu-dyn

Magnetic Effects on Topological Chiral Channels in Bilayer Graphene

We study the effect of a magnetic field on topological chiral channels of bilayer graphene at electric domain walls. The persistence of chiral edge states is attributed to the difference in valley Chern number in the regions of opposite electric field. We explore the regime of large electric and magnetic fields perpendicular to the lattice. The magnetic field shifts the channel away from our electric interface in a way that is inconsistent with the semiclassical expectation from the Lorentz force. Moreover, the magnetic field causes an imbalanced layer occupation preference to the chiral channels. These behaviors admit analytic solutions in the limits that either the electric or the magnetic field dominates. We numerically show in the general case that the system can be well-approximated as a weighted sum of the two limits.

cond-mat.str-el