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Abbas Karimi Rizi

Publications and source records attributed to Abbas Karimi Rizi.

2 recordsLinked to original sources

The strategy of survival for a competition between normal and anomalous diffusion

In this paper, we study the competition of two diffusion processes for achieving the maximum possible diffusion in an area. This competition, however, does not occur in the same circumstance; one of these processes is a normal diffusion with a higher growth rate, and another one is an anomalous diffusion with a lower growth rate. The trivial solution of the proposed model suggests that the winner is the one with the higher growth rate. But, the question is: what characteristics and strategies should the second diffusion include to prolong the survival in such a competition? The studied diffusion equations correspond to the SI model such that the anomalous diffusion has memory described by a fractional order derivative. The strategy promise that anomalous diffusion reaches maximum survival in case of forgetting some parts of the memory. This model can represent some of real phenomena, such as the contest of two companies in a market share, the spreading of two epidemic diseases, the diffusion of two species, or any reaction-diffusion related to real-world competition.

physics.soc-ph↗

Stability of Imbalanced Triangles in Gene Regulatory Networks of Cancerous and Normal Cells

Genes communicate with each other through different regulatory effects, which lead to the emergence of complex structures in cells, and such structures are expected to be different for normal and cancerous cells. To study breast cancer differences, we have investigated the Gene Regulatory Network (GRN) of cells as inferred from RNA-sequencing data. The GRN is a signed weighted network corresponding to the inductive or inhibitory interactions. Here we focus on a particular of motifs in the GRN, the triangles, which are imbalanced if the number of negative interactions are odd. By studying the stability of imbalanced triangles in the GRN, we show that the network of cancerous cells has fewer imbalanced triangles compared to normal. Moreover, in the normal cells, imbalanced triangles are isolated from the main part of the network, while such motifs are part of the network's giant component in cancerous cells. Our result demonstrates that due to genes' collective behavior the complex structures are different in cancerous cells from those in normal ones.

q-bio.MN↗