arXiv subjects

Abhinav Uppal

Publications and source records attributed to Abhinav Uppal.

7 recordsLinked to original sources

arXiv2026

Earable Platform with Integrated Simultaneous EEG Sensing and Auditory Stimulation

Conventional scalp-based EEG systems are cumbersome to use, requiring extensive setup, restrictive wiring, and conductive gels that can dry out and limit long-term monitoring, while also carrying social stigma. As a result, there is increasing interest in in-ear EEG technology to improve comfort, convenience, and discretion for users. This work presents a personalized in-ear EEG monitor (IEEM) that simultaneously captures EEG signals from the outer ear while delivering audio playback through the same device. The earpiece is custom-molded to precisely match the user's ear anatomy, providing effective sound isolation from the environment and enabling direct audio transmission into the ear canal. Testing of the assembled earpiece shows successful detection of electrooculography (EOG), eye blinks, jaw clenches, auditory steady-state responses (ASSR), and alpha modulation. Electrochemical impedance spectroscopy (EIS) measurements confirm stable electrode-skin contact, with impedance values similar to those of traditional dry electrodes. The integrated approach enables potential closed-loop neuromodulation applications all in the ear where brain activity can be monitored in real-time and corresponding acoustic stimulation delivered adaptively.

q-bio.NC↗

arXiv2026

Resting-State EEG Biomarkers of Tinnitus Robust to Cross-Subject and Cross-Platform Variation

Tinnitus is a prevalent auditory condition lacking objective biomarkers, motivating the search for reliable neural signatures. EEG, being a noninvasive method of brain imaging with a high temporal resolution provides a way to investigate the neural dynamics that may be associated with tinnitus. The generalizability of EEG-based tinnitus biomarkers across different datasets remains a critical challenge. Microstate theory has allowed for the characterization of quasi-stable topographic configurations in EEG, with some studies reporting altered microstate dynamics in tinnitus patients. This work seeks to improve upon existing dynamical systems analysis and their viability in identifying a robust biomarker. Dynamical features were extracted from two resting-state EEG datasets for the binary classification of tinnitus. Here, robustness is quantified as cross-dataset generalization, which is critical for clinical translation. We employ microstate analysis by identifying topographic states, from which transition probability and state duration features are derived. We also apply Koopman operator analysis through Dynamic Mode Decomposition (DMD) to dimensionality-reduced EEG to extract features in single-window. A linear SVM is trained on each feature set and evaluated in a cross-dataset generalization paradigm. PCA-based Koopman features yield the strongest discrimination metrics across both transfer directions, outperforming microstate-derived features. A Wasserstein-distance consistency analysis further reveals that Koopman eigenvalue \emph{magnitude}, encoding oscillation stability, generalizes across datasets ($\barρ = 0.685$), whereas eigenvalue \emph{phase}, encoding oscillation frequency, does not ($\barρ = 1.583$), providing interpretable evidence that altered oscillatory decay rates, rather than frequency shifts, constitute the more robust tinnitus biomarker.

q-bio.NC↗

arXiv2026

HiAER-Spike Software-Hardware Reconfigurable Platform for Event-Driven Neuromorphic Computing at Scale

In this work, we present HiAER-Spike, a modular, reconfigurable, event-driven neuromorphic computing platform designed to execute large spiking neural networks with up to 160 million neurons and 40 billion synapses - roughly twice the neurons of a mouse brain at faster than real time. This system, assembled at the UC San Diego Supercomputer Center, comprises a co-designed hard- and software stack that is optimized for run-time massively parallel processing and hierarchical address-event routing (HiAER) of spikes while promoting memory-efficient network storage and execution. The architecture efficiently handles both sparse connectivity and sparse activity for robust and low-latency event-driven inference for both edge and cloud computing. A Python programming interface to HiAER-Spike, agnostic to hardware-level detail, shields the user from complexity in the configuration and execution of general spiking neural networks with minimal constraints in topology. The system is made easily available over a web portal for use by the wider community. In the following, we provide an overview of the hard- and software stack, explain the underlying design principles, demonstrate some of the system's capabilities and solicit feedback from the broader neuromorphic community. Examples are shown demonstrating HiAER-Spike's capabilities for event-driven vision on benchmark CIFAR-10, DVS event-based gesture, MNIST, and Pong tasks.

cs.AR↗

arXiv2025

Perceptogram: Reconstructing Visual Percepts and Presumptive Electrode Preference from EEG

Visual neural decoding from EEG has improved significantly due to diffusion models that can reconstruct high-quality images from decoded latents. While recent works have focused on relatively complex architectures to achieve good reconstruction performance from EEG, less attention has been paid to the source of this information. We present a unified framework that not only enables image reconstruction from EEG using a simple linear decoder, but also isolates interpretable EEG feature maps that support visual perception. Unlike prior approaches that rely on deep, opaque models, our method leverages the inherent structure of CLIP embeddings to keep the mapping linear. We show that training a simple linear decoder from EEG to CLIP latent space, followed by a frozen pre-trained diffusion model, is sufficient to decode images with state-of-the-art reconstruction performance. Beyond reconstruction, Perceptogram enables the visualization of presumptive electrode preference and EEG patterns, revealing interpretable EEG feature maps that correspond to distinct visual attributes, such as semantic class, texture, and hue. We thus use our framework, Perceptogram, to probe EEG signals at various levels of the visual information hierarchy.

q-bio.NC↗

arXiv2025

Monkey Perceptogram: Reconstructing Visual Representation and Presumptive Neural Preference from Monkey Multi-electrode Arrays

Understanding how the primate brain transforms complex visual scenes into coherent perceptual experiences remains a central challenge in neuroscience. Here, we present a comprehensive framework for interpreting monkey visual processing by integrating encoding and decoding approaches applied to two large-scale spiking datasets recorded from macaque using THINGS images (THINGS macaque IT Dataset (TITD) and THINGS Ventral Stream Spiking Dataset (TVSD)). We leverage multi-electrode array recordings from the ventral visual stream--including V1, V4, and inferotemporal (IT) cortex--to investigate how distributed neural populations encode and represent visual information. Our approach employs linear models to decode spiking activity into multiple latent visual spaces (including CLIP and VDVAE embeddings) and reconstruct images using state-of-the-art generative models. We further utilize encoding models to map visual features back to neural activity, enabling visualization of the "preferred stimuli" that drive specific neural ensembles. Analyses of both datasets reveal that it is possible to reconstruct both low-level (e.g., color, texture) and high-level (e.g., semantic category) features of visual stimuli from population activity, with reconstructions preserving key perceptual attributes as quantified by feature-based similarity metrics. The spatiotemporal spike patterns reflect the ventral stream's hierarchical organization with anterior regions representing complex objects and categories. Functional clustering identifies feature-specific neural ensembles, with temporal dynamics show evolving feature selectivity post-stimulus. Our findings demonstrate feasible, generalizable perceptual reconstruction from large-scale monkey neural recordings, linking neural activity to perception.

q-bio.NC↗

arXiv2025

EEG Blink Artifacts Can Identify Read Music in Listening and Imagery

Eye-movement related artifacts including blinks and saccades are significantly larger in amplitude than cortical activity as recorded by scalp electroencephalography (EEG), but are typically discarded in EEG studies focusing on cognitive mechanisms as explained by cortical source activity. Accumulating evidence however indicates that spontaneous eye blinks are not necessarily random, and can be modulated by attention and cognition beyond just physiological necessities. In this exploratory analysis we reanalyze a public EEG dataset of musicians listening to or imagining music (Bach chorales) while simultaneously reading from a sheet of music. We ask whether blink timing in reading music, accompanied by listening or imagery, is sufficient to uniquely identify the music being read from a given score. Intra-subject blink counts and timing are compared across trials using a spike train distance metric (Victor and Purpura, 1997). One-trial-left-out cross-validation is used to identify the music being read with above chance level accuracy (best subject: 56\%, chance: 25\%), where accuracy is seen to vary with subject, condition, and a tunable cost factor for time shifts. Future studies may consider incorporating eye blink contributions to brain decoding, especially in wearables where eye blinks could be easier to record than EEG given their higher amplitudes.

q-bio.NC↗

arXiv2025

HiAER-Spike: Hardware-Software Co-Design for Large-Scale Reconfigurable Event-Driven Neuromorphic Computing

In this work, we present HiAER-Spike, a modular, reconfigurable, event-driven neuromorphic computing platform designed to execute large spiking neural networks with up to 160 million neurons and 40 billion synapses - roughly twice the neurons of a mouse brain at faster-than real-time. This system, which is currently under construction at the UC San Diego Supercomputing Center, comprises a co-designed hard- and software stack that is optimized for run-time massively parallel processing and hierarchical address-event routing (HiAER) of spikes while promoting memory-efficient network storage and execution. Our architecture efficiently handles both sparse connectivity and sparse activity for robust and low-latency event-driven inference for both edge and cloud computing. A Python programming interface to HiAER-Spike, agnostic to hardware-level detail, shields the user from complexity in the configuration and execution of general spiking neural networks with virtually no constraints in topology. The system is made easily available over a web portal for use by the wider community. In the following we provide an overview of the hard- and software stack, explain the underlying design principles, demonstrate some of the system's capabilities and solicit feedback from the broader neuromorphic community.

cs.NE↗