arXiv subjects

Adam Noel

Publications and source records attributed to Adam Noel.

At least 55 records · Page 3Linked to original sources

arXiv2016

Active Versus Passive: Receiver Model Transforms for Diffusive Molecular Communication

This paper presents an analytical comparison of active and passive receiver models in diffusive molecular communication. In the active model, molecules are absorbed when they collide with the receiver surface. In the passive model, the receiver is a virtual boundary that does not affect molecule behavior. Two approaches are presented to derive transforms between the receiver signals. As an example, two models for an unbounded diffusion-only molecular communication system with a spherical receiver are unified. As time increases in the three-dimensional system, the transform functions have constant scaling factors, such that the receiver models are effectively equivalent. Methods are presented to enable the transformation of stochastic simulations, which are used to verify the transforms and demonstrate that transforming the simulation of a passive receiver can be more efficient and more accurate than the direct simulation of an absorbing receiver.

cs.ET↗

arXiv2016

3D Stochastic Geometry Model for Large-Scale Molecular Communication Systems

Information delivery using chemical molecules is an integral part of biology at multiple distance scales and has attracted recent interest in bioengineering and communication. The collective signal strength at the receiver (i.e., the expected number of observed molecules inside the receiver), resulting from a large number of transmitters at random distances (e.g., due to mobility), can have a major impact on the reliability and efficiency of the molecular communication system. Modeling the collective signal from multiple diffusion sources can be computationally and analytically challenging. In this paper, we present the first tractable analytical model for the collective signal strength due to randomly-placed transmitters, whose positions are modelled as a homogeneous Poisson point process in three-dimensional (3D) space. By applying stochastic geometry, we derive analytical expressions for the expected number of observed molecules at a fully absorbing receiver and a passive receiver. Our results reveal that the collective signal strength at both types of receivers increases proportionally with increasing transmitter density. The proposed framework dramatically simplifies the analysis of large-scale molecular systems in both communication and biological applications.

cs.IT↗

arXiv2016

Modeling and Simulation of Molecular Communication Systems with a Reversible Adsorption Receiver

In this paper, we present an analytical model for the diffusive molecular communication (MC) system with a reversible adsorption receiver in a fluid environment. The widely used concentration shift keying (CSK) is considered for modulation. The time-varying spatial distribution of the information molecules under the reversible adsorption and desorption reaction at the surface of a receiver is analytically characterized. Based on the spatial distribution, we derive the net number of newly-adsorbed information molecules expected in any time duration. We further derive the number of newly-adsorbed molecules expected at the steady state to demonstrate the equilibrium concentration. Given the number of newly-adsorbed information molecules, the bit error probability of the proposed MC system is analytically approximated. Importantly, we present a simulation framework for the proposed model that accounts for the diffusion and reversible reaction. Simulation results show the accuracy of our derived expressions, and demonstrate the positive effect of the adsorption rate and the negative effect of the desorption rate on the error probability of reversible adsorption receiver with last transmit bit-1. Moreover, our analytical results simplify to the special cases of a full adsorption receiver and a partial adsorption receiver, both of which do not include desorption.

cs.ET↗

arXiv2016

Distributed Cooperative Detection for Multi-Receiver Molecular Communication

In this paper, a cooperative diffusion-based molecular communication system is considered where distributed receivers collaboratively determine a transmitter's signal. In this system, the receivers first make local hard decisions about the current transmitted bit and then report these decisions to a fusion center (FC). The FC combines the local hard decisions to make a global decision using an N-out-of-K fusion rule. Asymmetric and symmetric topologies are considered and for each topology, two reporting scenarios, namely, perfect reporting and noisy reporting, are addressed. Closed-form analytical expressions for the expected global error probability are derived for all considered topologies and scenarios. Numerical and simulation results show that system reliability can be greatly improved by combining the detection information of distributed receivers.

cs.IT↗

arXiv2016

Molecular Communication with a Reversible Adsorption Receiver

In this paper, we present an analytical model for a diffusive molecular communication (MC) system with a reversible adsorption receiver in a fluid environment. The time-varying spatial distribution of the information molecules under the reversible adsorption and desorption reaction at the surface of a bio-receiver is analytically characterized. Based on the spatial distribution, we derive the number of newly-adsorbed information molecules expected in any time duration. Importantly, we present a simulation framework for the proposed model that accounts for the diffusion and reversible reaction. Simulation results show the accuracy of our derived expressions, and demonstrate the positive effect of the adsorption rate and the negative effect of the desorption rate on the net number of newly-adsorbed information molecules expected. Moreover, our analytical results simplify to the special case of an absorbing receiver.

cs.IT↗

arXiv2015

Joint Channel Parameter Estimation via Diffusive Molecular Communication

The design and analysis of diffusive molecular communication systems generally requires knowledge of the environment's physical and chemical properties. Furthermore, prospective applications might rely on the timely detection of changes in the local system parameters. This paper studies the local estimation of channel parameters for diffusive molecular communication when a transmitter releases molecules that are observed by a receiver. The Fisher information matrix of the joint parameter estimation problem is derived so that the Cramer-Rao lower bound on the variance of locally unbiased estimation can be found. The joint estimation problem can be reduced to the estimation of any subset of the channel parameters. Maximum likelihood estimation leads to closed-form solutions for some single-parameter estimation problems and can otherwise be determined numerically. Peak-based estimators are proposed for low-complexity estimation of a single unknown parameter.

cs.IT↗

arXiv2015

On the Statistics of Reaction-Diffusion Simulations for Molecular Communication

A molecule traveling in a realistic propagation environment can experience stochastic interactions with other molecules and the environment boundary. The statistical behavior of some isolated phenomena, such as dilute unbounded molecular diffusion, are well understood. However, the coupling of multiple interactions can impede closed-form analysis, such that simulations are required to determine the statistics. This paper compares the statistics of molecular reaction-diffusion simulation models from the perspective of molecular communication systems. Microscopic methods track the location and state of every molecule, whereas mesoscopic methods partition the environment into virtual containers that hold molecules. The properties of each model are described and compared with a hybrid of both models. Simulation results also assess the accuracy of Poisson and Gaussian approximations of the underlying Binomial statistics.

physics.chem-ph↗

arXiv2015

Multi-Scale Stochastic Simulation for Diffusive Molecular Communication

Recently, hybrid models have emerged that combine microscopic and mesoscopic regimes in a single stochastic reaction-diffusion simulation. Microscopic simulations track every individual molecule and are generally more accurate. Mesoscopic simulations partition the environment into subvolumes, track when molecules move between adjacent subvolumes, and are generally more computationally efficient. In this paper, we present the foundation of a multi-scale stochastic simulator from the perspective of molecular communication, for both mesoscopic and hybrid models, where we emphasize simulation accuracy at the receiver and efficiency in regions that are far from the communication link. Our multi-scale models use subvolumes of different sizes, between which we derive the diffusion event transition rate. Simulation results compare the accuracy and efficiency of traditional approaches with that of a regular hybrid method and with those of our proposed multi-scale methods.

cs.ET↗

arXiv2015

Amplify-and-Forward Relaying in Two-Hop Diffusion-Based Molecular Communication Networks

This paper studies a three-node network in which an intermediate nano-transceiver, acting as a relay, is placed between a nano-transmitter and a nano-receiver to improve the range of diffusion-based molecular communication. Motivated by the relaying protocols used in traditional wireless communication systems, we study amplify-and-forward (AF) relaying with fixed and variable amplification factor for use in molecular communication systems. To this end, we derive a closed-form expression for the expected end-to-end error probability. Furthermore, we derive a closed-form expression for the optimal amplification factor at the relay node for minimization of an approximation of the expected error probability of the network. Our analytical and simulation results show the potential of AF relaying to improve the overall performance of nano-networks.

cs.IT↗

arXiv2014

The Unreasonable Effectiveness of Blood Pressure Measurement: Molecular Communication in Biological Systems

Arterial blood pressure is a key vital sign for the health of the human body. As such, accurate and reproducible measurement techniques are necessary for successful diagnosis. Blood pressure measurement is an example of molecular communication in regulated biological systems. In general, communication in regulated biological systems is difficult because the act of encoding information about the state of the system can corrupt the message itself. In this paper, we propose three strategies to cope with this problem to facilitate reliable molecular communication links: communicate from the outskirts; build it in; and leave a small footprint. Our strategies---inspired by communication in natural biological systems---provide a classification to guide the design of molecular communication mechanisms in synthetic biological systems. We illustrate our classification using examples of the first two strategies in natural systems. We then consider a molecular link within a model based on the Michaelis-Menten kinetics. In particular, we compute the capacity of the link, which reveals the potential of communicating using our leave a small footprint strategy. This provides a way of identifying whether the molecular link can be improved without affecting the function, and a guide to the design of synthetic biological systems.

cs.IT↗

arXiv2014

Analysis and Design of Multi-Hop Diffusion-Based Molecular Communication Networks

In this paper, we consider a multi-hop molecular communication network consisting of one nanotransmitter, one nanoreceiver, and multiple nanotransceivers acting as relays. We consider three different relaying schemes to improve the range of diffusion-based molecular communication. In the first scheme, different types of messenger molecules are utilized in each hop of the multi-hop network. In the second and third scheme, we assume that two types of molecules and one type of molecule are utilized in the network, respectively. We identify self-interference, backward intersymbol interference (backward-ISI), and forward-ISI as the performance-limiting effects for the second and third relaying schemes. Furthermore, we consider two relaying modes analogous to those used in wireless communication systems, namely full-duplex and half-duplex relaying. We propose the adaptation of the decision threshold as an effective mechanism to mitigate self-interference and backward-ISI at the relay for full-duplex and half-duplex transmission. We derive closed-form expressions for the expected end-to-end error probability of the network for the three considered relaying schemes. Furthermore, we derive closed-form expressions for the optimal number of molecules released by the nanotransmitter and the optimal detection threshold of the nanoreceiver for minimization of the expected error probability of each hop.

cs.IT↗

arXiv2014

Bounds on Distance Estimation via Diffusive Molecular Communication

This paper studies distance estimation for diffusive molecular communication. The Cramer-Rao lower bound on the variance of the distance estimation error is derived. The lower bound is derived for a physically unbounded environment with molecule degradation and steady uniform flow. The maximum likelihood distance estimator is derived and its accuracy is shown via simulation to perform very close to the Cramer-Rao lower bound. An existing protocol is shown to be equivalent to the maximum likelihood distance estimator if only one observation is made. Simulation results also show the accuracy of existing protocols with respect to the Cramer-Rao lower bound.

cs.IT↗

arXiv2014

Analysis and Design of Two-Hop Diffusion-Based Molecular Communication Networks

In this paper, we consider a two-hop molecular communication network consisting of one nanotransmitter, one nanoreceiver, and one nanotransceiver acting as a relay. We consider two different schemes for relaying to improve the range of diffusion-based molecular communication. In the first scheme, two different types of messenger molecules are utilized at the relay node for transmission and detection. In the second scheme, we assume that there is only one type of molecule available to be used as an information carrier. We identify self-interference as the performance-limiting effect for the second relaying scheme. Self-interference occurs when the relay must detect the same type of molecule that it also emits. Furthermore, we consider two relaying modes analogous to those used in wireless communication systems, i.e., full-duplex and half-duplex. In particular, while our main focus is on full-duplex relaying, half-duplex relaying is employed as a means to mitigate self-interference. In addition, we propose the adaptation of the decision threshold as an effective mechanism to mitigate self-interference at the relay for full-duplex transmission. We derive closed-form expressions for the expected error probability of the network for both considered relaying schemes.

cs.IT↗

arXiv2014

A Unifying Model for External Noise Sources and ISI in Diffusive Molecular Communication

This paper considers the impact of external noise sources, including interfering transmitters, on a diffusive molecular communication system, where the impact is measured as the number of noise molecules expected to be observed at a passive receiver. A unifying model for noise, multiuser interference, and intersymbol interference is presented, where, under certain circumstances, interference can be approximated as a noise source that is emitting continuously. The model includes the presence of advection and molecule degradation. The time-varying and asymptotic impact is derived for a series of special cases, some of which facilitate closed-form solutions. Simulation results show the accuracy of the expressions derived for the impact of a continuously-emitting noise source, and show how approximating intersymbol interference as a noise source can simplify the calculation of the expected bit error probability of a weighted sum detector.

cs.IT↗

arXiv2014

Optimal Receiver Design for Diffusive Molecular Communication With Flow and Additive Noise

In this paper, we perform receiver design for a diffusive molecular communication environment. Our model includes flow in any direction, sources of information molecules in addition to the transmitter, and enzymes in the propagation environment to mitigate intersymbol interference. We characterize the mutual information between receiver observations to show how often independent observations can be made. We derive the maximum likelihood sequence detector to provide a lower bound on the bit error probability. We propose the family of weighted sum detectors for more practical implementation and derive their expected bit error probability. Under certain conditions, the performance of the optimal weighted sum detector is shown to be equivalent to a matched filter. Receiver simulation results show the tradeoff in detector complexity versus achievable bit error probability, and that a slow flow in any direction can improve the performance of a weighted sum detector.

cs.IT↗

arXiv2014

Diffusive Molecular Communication with Disruptive Flows

In this paper, we study the performance of detectors in a diffusive molecular communication environment where steady uniform flow is present. We derive the expected number of information molecules to be observed in a passive spherical receiver, and determine the impact of flow on the assumption that the concentration of molecules throughout the receiver is uniform. Simulation results show the impact of advection on detector performance as a function of the flow's magnitude and direction. We highlight that there are disruptive flows, i.e., flows that are not in the direction of information transmission, that lead to an improvement in detector performance as long as the disruptive flow does not dominate diffusion and sufficient samples are taken.

cs.IT↗

arXiv2013

Improving Receiver Performance of Diffusive Molecular Communication with Enzymes

This paper studies the mitigation of intersymbol interference in a diffusive molecular communication system using enzymes that freely diffuse in the propagation environment. The enzymes form reaction intermediates with information molecules and then degrade them so that they cannot interfere with future transmissions. A lower bound expression on the expected number of molecules measured at the receiver is derived. A simple binary receiver detection scheme is proposed where the number of observed molecules is sampled at the time when the maximum number of molecules is expected. Insight is also provided into the selection of an appropriate bit interval. The expected bit error probability is derived as a function of the current and all previously transmitted bits. Simulation results show the accuracy of the bit error probability expression and the improvement in communication performance by having active enzymes present.

cs.IT↗

arXiv2013

Improving Diffusion-Based Molecular Communication with Unanchored Enzymes

In this paper, we propose adding enzymes to the propagation environment of a diffusive molecular communication system as a strategy for mitigating intersymbol interference. The enzymes form reaction intermediates with information molecules and then degrade them so that they have a smaller chance of interfering with future transmissions. We present the reaction-diffusion dynamics of this proposed system and derive a lower bound expression for the expected number of molecules observed at the receiver. We justify a particle-based simulation framework, and present simulation results that show both the accuracy of our expression and the potential for enzymes to improve communication performance.

cs.IT↗