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Adriano Barra

Publications and source records attributed to Adriano Barra.

At least 37 records · Page 2Linked to original sources

Parallel Learning by Multitasking Neural Networks

A modern challenge of Artificial Intelligence is learning multiple patterns at once (i.e.parallel learning). While this can not be accomplished by standard Hebbian associative neural networks, in this paper we show how the Multitasking Hebbian Network (a variation on theme of the Hopfield model working on sparse data-sets) is naturally able to perform this complex task. We focus on systems processing in parallel a finite (up to logarithmic growth in the size of the network) amount of patterns, mirroring the low-storage level of standard associative neural networks at work with pattern recognition. For mild dilution in the patterns, the network handles them hierarchically, distributing the amplitudes of their signals as power-laws w.r.t. their information content (hierarchical regime), while, for strong dilution, all the signals pertaining to all the patterns are raised with the same strength (parallel regime). Further, confined to the low-storage setting (i.e., far from the spin glass limit), the presence of a teacher neither alters the multitasking performances nor changes the thresholds for learning: the latter are the same whatever the training protocol is supervised or unsupervised. Results obtained through statistical mechanics, signal-to-noise technique and Monte Carlo simulations are overall in perfect agreement and carry interesting insights on multiple learning at once: for instance, whenever the cost-function of the model is minimized in parallel on several patterns (in its description via Statistical Mechanics), the same happens to the standard sum-squared error Loss function (typically used in Machine Learning).

cond-mat.dis-nn↗

Statistical Mechanics of Learning via Reverberation in Bidirectional Associative Memories

We study bi-directional associative neural networks that, exposed to noisy examples of an extensive number of random archetypes, learn the latter (with or without the presence of a teacher) when the supplied information is enough: in this setting, learning is heteroassociative -- involving couples of patterns -- and it is achieved by reverberating the information depicted from the examples through the layers of the network. By adapting Guerra's interpolation technique, we provide a full statistical mechanical picture of supervised and unsupervised learning processes (at the replica symmetric level of description) obtaining analytically phase diagrams, thresholds for learning, a picture of the ground-state in plain agreement with Monte Carlo simulations and signal-to-noise outcomes. In the large dataset limit, the Kosko storage prescription as well as its statistical mechanical picture provided by Kurchan, Peliti, and Saber in the eighties is fully recovered. Computational advantages in dealing with information reverberation, rather than storage, are discussed for natural test cases. In particular, we show how this network admits an integral representation in terms of two coupled restricted Boltzmann machines, whose hidden layers are entirely built of by grand-mother neurons, to prove that by coupling solely these grand-mother neurons we can correlate the patterns they are related to: it is thus possible to recover Pavlov's Classical Conditioning by adding just one synapse among the correct grand-mother neurons (hence saving an extensive number of these links for further information storage w.r.t. the classical autoassociative setting).

cond-mat.dis-nn↗

Dense Hebbian neural networks: a replica symmetric picture of unsupervised learning

We consider dense, associative neural-networks trained with no supervision and we investigate their computational capabilities analytically, via a statistical-mechanics approach, and numerically, via Monte Carlo simulations. In particular, we obtain a phase diagram summarizing their performance as a function of the control parameters such as the quality and quantity of the training dataset and the network storage, valid in the limit of large network size and structureless datasets. Moreover, we establish a bridge between macroscopic observables standardly used in statistical mechanics and loss functions typically used in the machine learning. As technical remarks, from the analytic side, we implement large deviations and stability analysis within Guerra's interpolation to tackle the not-Gaussian distributions involved in the post-synaptic potentials while, from the computational counterpart, we insert Plefka approximation in the Monte Carlo scheme, to speed up the evaluation of the synaptic tensors, overall obtaining a novel and broad approach to investigate neural networks in general.

cond-mat.dis-nn↗

Dense Hebbian neural networks: a replica symmetric picture of supervised learning

We consider dense, associative neural-networks trained by a teacher (i.e., with supervision) and we investigate their computational capabilities analytically, via statistical-mechanics of spin glasses, and numerically, via Monte Carlo simulations. In particular, we obtain a phase diagram summarizing their performance as a function of the control parameters such as quality and quantity of the training dataset, network storage and noise, that is valid in the limit of large network size and structureless datasets: these networks may work in a ultra-storage regime (where they can handle a huge amount of patterns, if compared with shallow neural networks) or in a ultra-detection regime (where they can perform pattern recognition at prohibitive signal-to-noise ratios, if compared with shallow neural networks). Guided by the random theory as a reference framework, we also test numerically learning, storing and retrieval capabilities shown by these networks on structured datasets as MNist and Fashion MNist. As technical remarks, from the analytic side, we implement large deviations and stability analysis within Guerra's interpolation to tackle the not-Gaussian distributions involved in the post-synaptic potentials while, from the computational counterpart, we insert Plefka approximation in the Monte Carlo scheme, to speed up the evaluation of the synaptic tensors, overall obtaining a novel and broad approach to investigate supervised learning in neural networks, beyond the shallow limit, in general.

cond-mat.dis-nn↗

Ultrametric identities in glassy models of Natural Evolution

Spin-glasses constitute a well-grounded framework for evolutionary models. Of particular interest for (some of) these models is the lack of self-averaging of their order parameters (e.g. the Hamming distance between the genomes of two individuals), even in asymptotic limits, much as like the behavior of the overlap between the configurations of two replica in mean-field spin-glasses. In the latter, this lack of self-averaging is related to peculiar fluctuations of the overlap, known as Ghirlanda-Guerra identities and Aizenman-Contucci polynomials, that cover a pivotal role in describing the ultrametric structure of the spin-glass landscape. As for evolutionary models, such identities may therefore be related to a taxonomic classification of individuals, yet a full investigation on their validity is missing. In this paper, we study ultrametric identities in simple cases where solely random mutations take place, while selective pressure is absent, namely in {\em flat landscape} models. In particular, we study three paradigmatic models in this setting: the {\em one parent model} (which, by construction, is ultrametric at the level of single individuals), the {\em homogeneous population model} (which is replica symmetric), and the {\em species formation model} (where a broken-replica scenario emerges at the level of species). We find analytical and numerical evidence that in the first and in the third model nor the Ghirlanda-Guerra neither the Aizenman-Contucci constraints hold, rather a new class of ultrametric identities is satisfied; in the second model all these constraints hold trivially. Very preliminary results on a real biological human genome derived by {\em The 1000 Genome Project Consortium} and on two artificial human genomes (generated by two different types neural networks) seem in better agreement with these new identities rather than the classic ones.

cond-mat.dis-nn↗

Thermodynamics of bidirectional associative memories

In this paper we investigate the equilibrium properties of bidirectional associative memories (BAMs). Introduced by Kosko in 1988 as a generalization of the Hopfield model to a bipartite structure, the simplest architecture is defined by two layers of neurons, with synaptic connections only between units of different layers: even without internal connections within each layer, information storage and retrieval are still possible through the reverberation of neural activities passing from one layer to another. We characterize the computational capabilities of a stochastic extension of this model in the thermodynamic limit, by applying rigorous techniques from statistical physics. A detailed picture of the phase diagram at the replica symmetric level is provided, both at finite temperature and in the noiseless regimes. Also for the latter, the critical load is further investigated up to one step of replica symmetry breaking. An analytical and numerical inspection of the transition curves (namely critical lines splitting the various modes of operation of the machine) is carried out as the control parameters - noise, load and asymmetry between the two layer sizes - are tuned. In particular, with a finite asymmetry between the two layers, it is shown how the BAM can store information more efficiently than the Hopfield model by requiring less parameters to encode a fixed number of patterns. Comparisons are made with numerical simulations of neural dynamics. Finally, a low-load analysis is carried out to explain the retrieval mechanism in the BAM by analogy with two interacting Hopfield models. A potential equivalence with two coupled Restricted Boltmzann Machines is also discussed.

cond-mat.dis-nn↗

Supervised Hebbian Learning

In neural network's Literature, Hebbian learning traditionally refers to the procedure by which the Hopfield model and its generalizations store archetypes (i.e., definite patterns that are experienced just once to form the synaptic matrix). However, the term "Learning" in Machine Learning refers to the ability of the machine to extract features from the supplied dataset (e.g., made of blurred examples of these archetypes), in order to make its own representation of the unavailable archetypes. Here, given a sample of examples, we define a supervised learning protocol by which the Hopfield network can infer the archetypes, and we detect the correct control parameters (including size and quality of the dataset) to depict a phase diagram for the system performance. We also prove that, for structureless datasets, the Hopfield model equipped with this supervised learning rule is equivalent to a restricted Boltzmann machine and this suggests an optimal and interpretable training routine. Finally, this approach is generalized to structured datasets: we highlight a quasi-ultrametric organization (reminiscent of replica-symmetry-breaking) in the analyzed datasets and, consequently, we introduce an additional "replica hidden layer" for its (partial) disentanglement, which is shown to improve MNIST classification from 75% to 95%, and to offer a new perspective on deep architectures.

cond-mat.dis-nn↗

Pavlov Learning Machines

As well known, Hebb's learning traces its origin in Pavlov's Classical Conditioning, however, while the former has been extensively modelled in the past decades (e.g., by Hopfield model and countless variations on theme), as for the latter modelling has remained largely unaddressed so far; further, a bridge between these two pillars is totally lacking. The main difficulty towards this goal lays in the intrinsically different scales of the information involved: Pavlov's theory is about correlations among \emph{concepts} that are (dynamically) stored in the synaptic matrix as exemplified by the celebrated experiment starring a dog and a ring bell; conversely, Hebb's theory is about correlations among pairs of adjacent neurons as summarized by the famous statement {\em neurons that fire together wire together}. In this paper we rely on stochastic-process theory and model neural and synaptic dynamics via Langevin equations, to prove that -- as long as we keep neurons' and synapses' timescales largely split -- Pavlov mechanism spontaneously takes place and ultimately gives rise to synaptic weights that recover the Hebbian kernel.

cond-mat.dis-nn↗

Recurrent neural networks that generalize from examples and optimize by dreaming

The gap between the huge volumes of data needed to train artificial neural networks and the relatively small amount of data needed by their biological counterparts is a central puzzle in machine learning. Here, inspired by biological information-processing, we introduce a generalized Hopfield network where pairwise couplings between neurons are built according to Hebb's prescription for on-line learning and allow also for (suitably stylized) off-line sleeping mechanisms. Moreover, in order to retain a learning framework, here the patterns are not assumed to be available, instead, we let the network experience solely a dataset made of a sample of noisy examples for each pattern. We analyze the model by statistical-mechanics tools and we obtain a quantitative picture of its capabilities as functions of its control parameters: the resulting network is an associative memory for pattern recognition that learns from examples on-line, generalizes and optimizes its storage capacity by off-line sleeping. Remarkably, the sleeping mechanisms always significantly reduce (up to $\approx 90\%$) the dataset size required to correctly generalize, further, there are memory loads that are prohibitive to Hebbian networks without sleeping (no matter the size and quality of the provided examples), but that are easily handled by the present "rested" neural networks.

cond-mat.dis-nn↗

Replica symmetry breaking in dense neural networks

Understanding the glassy nature of neural networks is pivotal both for theoretical and computational advances in Machine Learning and Theoretical Artificial Intelligence. Keeping the focus on dense associative Hebbian neural networks, the purpose of this paper is two-fold: at first we develop rigorous mathematical approaches to address properly a statistical mechanical picture of the phenomenon of {\em replica symmetry breaking} (RSB) in these networks, then -- deepening results stemmed via these routes -- we aim to inspect the {\em glassiness} that they hide. In particular, regarding the methodology, we provide two techniques: the former is an adaptation of the transport PDE to the case, while the latter is an extension of Guerra's interpolation breakthrough. Beyond coherence among the results, either in replica symmetric and in the one-step replica symmetry breaking level of description, we prove the Gardner's picture and we identify the maximal storage capacity by a ground-state analysis in the Baldi-Venkatesh high-storage regime. In the second part of the paper we investigate the glassy structure of these networks: in contrast with the replica symmetric scenario (RS), RSB actually stabilizes the spin-glass phase. We report huge differences w.r.t. the standard pairwise Hopfield limit: in particular, it is known that it is possible to express the free energy of the Hopfield neural network as a linear combination of the free energies of an hard spin glass (i.e. the Sherrington-Kirkpatrick model) and a soft spin glass (the Gaussian or "spherical" model). This is no longer true when interactions are more than pairwise (whatever the level of description, RS or RSB): for dense networks solely the free energy of the hard spin glass survives, proving a huge diversity in the underlying glassiness of associative neural networks.

cond-mat.dis-nn↗

The emergence of a concept in shallow neural networks

We consider restricted Boltzmann machine (RBMs) trained over an unstructured dataset made of blurred copies of definite but unavailable ``archetypes'' and we show that there exists a critical sample size beyond which the RBM can learn archetypes, namely the machine can successfully play as a generative model or as a classifier, according to the operational routine. In general, assessing a critical sample size (possibly in relation to the quality of the dataset) is still an open problem in machine learning. Here, restricting to the random theory, where shallow networks suffice and the grand-mother cell scenario is correct, we leverage the formal equivalence between RBMs and Hopfield networks, to obtain a phase diagram for both the neural architectures which highlights regions, in the space of the control parameters (i.e., number of archetypes, number of neurons, size and quality of the training set), where learning can be accomplished. Our investigations are led by analytical methods based on the statistical-mechanics of disordered systems and results are further corroborated by extensive Monte Carlo simulations.

cond-mat.dis-nn↗

Towards the development of human immune-system-on-a-chip platforms

Organ-on-a-chip (OoCs) platforms could revolutionize drug discovery and might ultimately become essential tools for precision therapy. Although many single-organ and interconnected systems have been described, the immune system has been comparatively neglected, despite its pervasive role in the body and the trend towards newer therapeutic products (i.e., complex biologics, nanoparticles, immune checkpoint inhibitors, and engineered T cells) that often cause, or are based on, immune reactions. In this review, we recapitulate some distinctive features of the immune system before reviewing microfluidic devices that mimic lymphoid organs or other organs and/or tissues with an integrated immune system component.

physics.bio-ph↗

Replica symmetry breaking in neural networks: a few steps toward rigorous results

In this paper we adapt the broken replica interpolation technique (developed by Francesco Guerra to deal with the Sherrington-Kirkpatrick model, namely a pairwise mean-field spin-glass whose couplings are i.i.d. standard Gaussian variables) in order to work also with the Hopfield model (i.e., a pairwise mean-field neural-network whose couplings are drawn according to Hebb's learning rule): this is accomplished by grafting Guerra's telescopic averages on the transport equation technique, recently developed by some of the Authors. As an overture, we apply the technique to solve the Sherrington-Kirkpatrick model with i.i.d. Gaussian couplings centered at $J_0$ and with finite variance $J$; the mean $J_0$ plays the role of a signal to be detected in a noisy environment tuned by $J$, hence making this model a natural test-case to be investigated before addressing the Hopfield model. For both the models, an explicit expression of their quenched free energy in terms of their natural order parameters is obtained at the K-th step (K arbitrary, but finite) of replica-symmetry-breaking. In particular, for the Hopfield model, by assuming that the overlaps respect Parisi's decomposition (following the ziqqurat ansatz) and that the Mattis magnetization is self-averaging, we recover previous results obtained via replica-trick by Amit, Crisanti and Gutfreund (1RSB) and by Steffan and Kühn (2RSB).

math-ph↗

Generalized Guerra's interpolation schemes for dense associative neural networks

In this work we develop analytical techniques to investigate a broad class of associative neural networks set in the high-storage regime. These techniques translate the original statistical-mechanical problem into an analytical-mechanical one which implies solving a set of partial differential equations, rather than tackling the canonical probabilistic route. We test the method on the classical Hopfield model - where the cost function includes only two-body interactions (i.e., quadratic terms) - and on the "relativistic" Hopfield model - where the (expansion of the) cost function includes p-body (i.e., of degree p) contributions. Under the replica symmetric assumption, we paint the phase diagrams of these models by obtaining the explicit expression of their free energy as a function of the model parameters (i.e., noise level and memory storage). Further, since for non-pairwise models ergodicity breaking is non necessarily a critical phenomenon, we develop a fluctuation analysis and find that criticality is preserved in the relativistic model.

cond-mat.dis-nn↗

Annealing and replica-symmetry in Deep Boltzmann Machines

In this paper we study the properties of the quenched pressure of a multi-layer spin-glass model (a deep Boltzmann Machine in artificial intelligence jargon) whose pairwise interactions are allowed between spins lying in adjacent layers and not inside the same layer nor among layers at distance larger than one. We prove a theorem that bounds the quenched pressure of such a K-layer machine in terms of K Sherrington-Kirkpatrick spin glasses and use it to investigate its annealed region. The replica-symmetric approximation of the quenched pressure is identified and its relation to the annealed one is considered. The paper also presents some observation on the model's architectural structure related to machine learning. Since escaping the annealed region is mandatory for a meaningful training, by squeezing such region we obtain thermodynamical constraints on the form factors. Remarkably, its optimal escape is achieved by requiring the last layer to scale sub-linearly in the network size.

cond-mat.stat-mech↗

A statistical-inference approach to reconstruct inter-cellular interactions in cell-migration experiments

Migration of cells can be characterized by two, prototypical types of motion: individual and collective migration. We propose a statistical-inference approach designed to detect the presence of cell-cell interactions that give rise to collective behaviors in cell-motility experiments. Such inference method has been first successfully tested on synthetic motional data, and then applied to two experiments. In the first experiment, cell migrate in a wound-healing model: when applied to this experiment, the inference method predicts the existence of cell-cell interactions, correctly mirroring the strong intercellular contacts which are present in the experiment. In the second experiment, dendritic cells migrate in a chemokine gradient. Our inference analysis does not provide evidence for interactions, indicating that cells migrate by sensing independently the chemokine source. According to this prediction, we speculate that mature dendritic cells disregard inter-cellular signals that could otherwise delay their arrival to lymph vessels.

q-bio.CB↗

Neural networks with redundant representation: detecting the undetectable

We consider a three-layer Sejnowski machine and show that features learnt via contrastive divergence have a dual representation as patterns in a dense associative memory of order P=4. The latter is known to be able to Hebbian-store an amount of patterns scaling as N^{P-1}, where N denotes the number of constituting binary neurons interacting P-wisely. We also prove that, by keeping the dense associative network far from the saturation regime (namely, allowing for a number of patterns scaling only linearly with N, while P>2) such a system is able to perform pattern recognition far below the standard signal-to-noise threshold. In particular, a network with P=4 is able to retrieve information whose intensity is O(1) even in the presence of a noise O(\sqrt{N}) in the large N limit. This striking skill stems from a redundancy representation of patterns -- which is afforded given the (relatively) low-load information storage -- and it contributes to explain the impressive abilities in pattern recognition exhibited by new-generation neural networks. The whole theory is developed rigorously, at the replica symmetric level of approximation, and corroborated by signal-to-noise analysis and Monte Carlo simulations.

cond-mat.dis-nn↗

Free energies of Boltzmann Machines: self-averaging, annealed and replica symmetric approximations in the thermodynamic limit

Restricted Boltzmann machines (RBMs) constitute one of the main models for machine statistical inference and they are widely employed in Artificial Intelligence as powerful tools for (deep) learning. However, in contrast with countless remarkable practical successes, their mathematical formalization has been largely elusive: from a statistical-mechanics perspective these systems display the same (random) Gibbs measure of bi-partite spin-glasses, whose rigorous treatment is notoriously difficult. In this work, beyond providing a brief review on RBMs from both the learning and the retrieval perspectives, we aim to contribute to their analytical investigation, by considering two distinct realizations of their weights (i.e., Boolean and Gaussian) and studying the properties of their related free energies. More precisely, focusing on a RBM characterized by digital couplings, we first extend the Pastur-Shcherbina-Tirozzi method (originally developed for the Hopfield model) to prove the self-averaging property for the free energy, over its quenched expectation, in the infinite volume limit, then we explicitly calculate its simplest approximation, namely its annealed bound. Next, focusing on a RBM characterized by analogical weights, we extend Guerra's interpolating scheme to obtain a control of the quenched free-energy under the assumption of replica symmetry: we get self-consistencies for the order parameters (in full agreement with the existing Literature) as well as the critical line for ergodicity breaking that turns out to be the same obtained in AGS theory. As we discuss, this analogy stems from the slow-noise universality. Finally, glancing beyond replica symmetry, we analyze the fluctuations of the overlaps for an estimate of the (slow) noise affecting the retrieval of the signal, and by a stability analysis we recover the Aizenman-Contucci identities typical of glassy systems.

cond-mat.dis-nn↗