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Ahmad Fall

Publications and source records attributed to Ahmad Fall.

4 recordsLinked to original sources

Are Tabular Foundation Models Robust to Realistic Query Distribution Shifts in Microbiome Data?

Tabular foundation models (TFMs) achieve strong performance on microbiome abundance data, yet their robustness under realistic distribution shift remains poorly characterized. We introduce a benchmark that evaluates the robustness of TFMs to biologically inspired perturbations across six gut microbiome datasets spanning four disease contexts. In this in-context learning setting, models receive unperturbed support sets as context and are evaluated on perturbed query samples. To isolate robustness beyond "shortcut" features, we preserve the most discriminative taxa and apply three controlled perturbation strategies: (i) removal of high-abundance (uninformative) taxa, (ii) sparsification via increased zero-inflation, and (iii) zero-imputation via spurious non-zero injections. Our results show that protecting discriminative features is insufficient to guarantee stability under support-query shift: across datasets, all perturbations degrade model performance, with zero-imputation consistently the most harmful, indicating that corrupting global feature structure can break generalization even when key taxa are retained. Sparsification disproportionately affects TFMs relative to a classical random forest baseline, suggesting greater sensitivity to zero-inflation-type shifts. The code is publicly available at: https://github.com/UMMISCO/metagenomics-fm/.

cs.LG

IKrNet: A Neural Network for Detecting Specific Drug-Induced Patterns in Electrocardiograms Amidst Physiological Variability

Monitoring and analyzing electrocardiogram (ECG) signals, even under varying physiological conditions, including those influenced by physical activity, drugs and stress, is crucial to accurately assess cardiac health. However, current AI-based methods often fail to account for how these factors interact and alter ECG patterns, ultimately limiting their applicability in real-world settings. This study introduces IKrNet, a novel neural network model, which identifies drug-specific patterns in ECGs amidst certain physiological conditions. IKrNet's architecture incorporates spatial and temporal dynamics by using a convolutional backbone with varying receptive field size to capture spatial features. A bi-directional Long Short-Term Memory module is also employed to model temporal dependencies. By treating heart rate variability as a surrogate for physiological fluctuations, we evaluated IKrNet's performance across diverse scenarios, including conditions with physical stress, drug intake alone, and a baseline without drug presence. Our assessment follows a clinical protocol in which 990 healthy volunteers were administered 80mg of Sotalol, a drug which is known to be a precursor to Torsades-de-Pointes, a life-threatening arrhythmia. We show that IKrNet outperforms state-of-the-art models' accuracy and stability in varying physiological conditions, underscoring its clinical viability.

cs.CV

ECGtizer: a fully automated digitizing and signal recovery pipeline for electrocardiograms

Electrocardiograms (ECGs) are essential for diagnosing cardiac pathologies, yet traditional paper-based ECG storage poses significant challenges for automated analysis. This study introduces ECGtizer, an open-source, fully automated tool designed to digitize paper ECGs and recover signals lost during storage. ECGtizer facilitates automated analyses using modern AI methods. It employs automated lead detection, three pixel-based signal extraction algorithms, and a deep learning-based signal reconstruction module. We evaluated ECGtizer on two datasets: a real-life cohort from the COVID-19 pandemic (JOCOVID) and a publicly available dataset (PTB-XL). Performance was compared with two existing methods: the fully automated ECGminer and the semi-automated PaperECG, which requires human intervention. ECGtizer's performance was assessed in terms of signal recovery and the fidelity of clinically relevant feature measurement. Additionally, we tested these tools on a third dataset (GENEREPOL) for downstream AI tasks. Results show that ECGtizer outperforms existing tools, with its ECGtizerFrag algorithm delivering superior signal recovery. While PaperECG demonstrated better outcomes than ECGminer, it required human input. ECGtizer enhances the usability of historical ECG data and supports advanced AI-based diagnostic methods, making it a valuable addition to the field of AI in ECG analysis.

eess.SP

ECGrecover: a Deep Learning Approach for Electrocardiogram Signal Completion

In this work, we address the challenge of reconstructing the complete 12-lead ECG signal from its incomplete parts. We focus on two main scenarios: (i) reconstructing missing signal segments within an ECG lead and (ii) recovering entire leads from signal in another unique lead. Two emerging clinical applications emphasize the relevance of our work. The first is the increasing need to digitize paper-stored ECGs for utilization in AI-based applications, often limited to digital 12 lead 10s ECGs. The second is the widespread use of wearable devices that record ECGs but typically capture only one or a few leads. In both cases, a non-negligible amount of information is lost or not recorded. Our approach aims to recover this missing signal. We propose ECGrecover, a U-Net neural network model trained on a novel composite objective function to address the reconstruction problem. This function incorporates both spatial and temporal features of the ECG by combining the distance in amplitude and sycnhronization through time between the reconstructed and the real digital signals. We used real-life ECG datasets and through comprehensive assessments compared ECGrecover with three state-of-the-art methods based on generative adversarial networks (EKGAN, Pix2Pix) as well as the CopyPaste strategy. The results demonstrated that ECGrecover consistently outperformed state-of-the-art methods in standard distortion metrics as well as in preserving critical ECG characteristics, particularly the P, QRS, and T wave coordinates.

eess.SP