arXiv subjects

Ahmed M Salih

Publications and source records attributed to Ahmed M Salih.

6 recordsLinked to original sources

arXiv2026

Regulatory Approval Is Not Enough: Gaps in Trustworthy AI Reporting in FDA-Cleared Medical Devices

Background: AI/ML-enabled medical devices are increasingly deployed in healthcare under evolving regulatory frameworks. As these systems become more integrated into clinical decision-making, there is growing expectation that they demonstrate key dimensions of trustworthy AI to support clinician, patient, and public trust. Whether publicly available regulatory documentation provides sufficient evidence to independently assess the trustworthiness of cleared AI systems remains unclear. Methods: We analysed FDA AI/ML-enabled medical device summary reports published between 2021 and 2025. Reports underwent automated keyword screening followed by multi-stage manual consensus review to identify documented evidence for the six FUTURE-AI principles: Fairness, Universality, Traceability, Usability, Robustness, and Explainability. Descriptive, temporal, and clinical-domain analyses were performed. Multivariable logistic regression assessed whether year of clearance or clinical domain predicted higher reporting transparency, defined as evidence reported for three or more principles. Results: Of 1,105 FDA summary reports screened, 519 were included. Trustworthy AI reporting was limited and uneven. Nearly one quarter (24.7%) provided no evidence for any principle, and none documented evidence across all six. Robustness was most frequently reported (57.6%), while Traceability (8.3%) and Explainability (3.5%) were the most pronounced gaps. Neither year of clearance (OR 1.02, 95% CI 0.88-1.19) nor clinical domain (OR 0.73, 95% CI 0.46-1.15) predicted higher reporting transparency. Interpretation: Substantial, persistent trustworthy AI reporting gaps exist in FDA documentation. Regulatory approval alone should not be considered a proxy for trustworthiness. Standardised, audit-ready reporting across the AI lifecycle is needed to support independent assessment and responsible adoption of healthcare AI.

cs.CY↗

arXiv2026

Explainable Artificial Intelligence For The Detection and Characterisation of Stage B Heart Failure

Stage B heart failure is characterized by asymptomatic structural or functional cardiac abnormalities. Identifying individuals at this stage is clinically important, as early detection may enable targeted interventions to prevent progression to symptomatic disease. Explainable artificial intelligence (XAI) may support early detection, transparent risk stratification, and selection of clinically actionable interventions. This review examines the use of XAI in detecting and characterizing stage B heart failure. A literature search of Web of Science, Scopus, and PubMed was conducted on 27 March 2026. Studies were included if they applied AI with XAI techniques to stage B heart failure. After screening, 20 studies were included. Data on modalities, outcomes, demographic reporting, and XAI methods were extracted and synthesized. SHAP was the most commonly used method, followed by LIME, saliency maps, and Grad-CAM; however, XAI adoption was inconsistent, with some studies relying on limited or ad hoc interpretability approaches. Notably, none compared explanations across sex or ethnic subgroups, despite evidence of subgroup differences in disease burden. Evaluation of XAI outputs was often insufficient: some studies did not assess explanations, while others relied only on literature-based comparisons, introducing potential bias. These limitations suggest explainability was not systematically validated or leveraged to support robust and fair clinical inference. XAI shows promise for improving transparency in stage B heart failure identification, but current implementations remain limited. Key gaps include limited consideration of sex and ethnicity, absence of subgroup-specific analyses, inconsistent evaluation, and lack of external validation, all of which constrain generalisability and clinical adoption.

cs.CY↗

arXiv2024

Explainable Artificial Intelligence for Dependent Features: Additive Effects of Collinearity

Explainable Artificial Intelligence (XAI) emerged to reveal the internal mechanism of machine learning models and how the features affect the prediction outcome. Collinearity is one of the big issues that XAI methods face when identifying the most informative features in the model. Current XAI approaches assume the features in the models are independent and calculate the effect of each feature toward model prediction independently from the rest of the features. However, such assumption is not realistic in real life applications. We propose an Additive Effects of Collinearity (AEC) as a novel XAI method that aim to considers the collinearity issue when it models the effect of each feature in the model on the outcome. AEC is based on the idea of dividing multivariate models into several univariate models in order to examine their impact on each other and consequently on the outcome. The proposed method is implemented using simulated and real data to validate its efficiency comparing with the a state of arts XAI method. The results indicate that AEC is more robust and stable against the impact of collinearity when it explains AI models compared with the state of arts XAI method.

cs.LG↗

arXiv2024

Common Steps in Machine Learning Might Hinder The Explainability Aims in Medicine

Data pre-processing is a significant step in machine learning to improve the performance of the model and decreases the running time. This might include dealing with missing values, outliers detection and removing, data augmentation, dimensionality reduction, data normalization and handling the impact of confounding variables. Although it is found the steps improve the accuracy of the model, but they might hinder the explainability of the model if they are not carefully considered especially in medicine. They might block new findings when missing values and outliers removal are implemented inappropriately. In addition, they might make the model unfair against all the groups in the model when making the decision. Moreover, they turn the features into unitless and clinically meaningless and consequently not explainable. This paper discusses the common steps of the data preprocessing in machine learning and their impacts on the explainability and interpretability of the model. Finally, the paper discusses some possible solutions that improve the performance of the model while not decreasing its explainability.

cs.LG↗

arXiv2024

Are Linear Regression Models White Box and Interpretable?

Explainable artificial intelligence (XAI) is a set of tools and algorithms that applied or embedded to machine learning models to understand and interpret the models. They are recommended especially for complex or advanced models including deep neural network because they are not interpretable from human point of view. On the other hand, simple models including linear regression are easy to implement, has less computational complexity and easy to visualize the output. The common notion in the literature that simple models including linear regression are considered as "white box" because they are more interpretable and easier to understand. This is based on the idea that linear regression models have several favorable outcomes including the effect of the features in the model and whether they affect positively or negatively toward model output. Moreover, uncertainty of the model can be measured or estimated using the confidence interval. However, we argue that this perception is not accurate and linear regression models are not easy to interpret neither easy to understand considering common XAI metrics and possible challenges might face. This includes linearity, local explanation, multicollinearity, covariates, normalization, uncertainty, features contribution and fairness. Consequently, we recommend the so-called simple models should be treated equally to complex models when it comes to explainability and interpretability.

cs.LG↗

arXiv2024

Explainable Artificial Intelligence and Multicollinearity : A Mini Review of Current Approaches

Explainable Artificial Intelligence (XAI) methods help to understand the internal mechanism of machine learning models and how they reach a specific decision or made a specific action. The list of informative features is one of the most common output of XAI methods. Multicollinearity is one of the big issue that should be considered when XAI generates the explanation in terms of the most informative features in an AI system. No review has been dedicated to investigate the current approaches to handle such significant issue. In this paper, we provide a review of the current state-of-the-art approaches in relation to the XAI in the context of recent advances in dealing with the multicollinearity issue. To do so, we searched in three repositories that are: Web of Science, Scopus and IEEE Xplore to find pertinent published papers. After excluding irrelevant papers, seven papers were considered in the review. In addition, we discuss the current XAI methods and their limitations in dealing with the multicollinearity and suggest future directions.

cs.AI↗