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Ahmed Tahseen Minhaz

Publications and source records attributed to Ahmed Tahseen Minhaz.

2 recordsLinked to original sources

Multitask Conditional Generative Adversarial Network Enables Automatic Whole Knee Cartilage and Menisci Segmentation and Reliable $T_{1ρ}$ and $T_2$ Quantification Without High-Resolution Morphological Images

Early osteoarthritis detection through quantitative MRI (qMRI) requires accurate cartilage and meniscus segmentation, traditionally necessitating time-consuming, costly 3D high-resolution Double Echo Steady-State (DESS) MRI scans. This study developed a multi-task conditional generative adversarial network (MT-cGAN) to simultaneously synthesize DESS-like images and segment tissues directly from qMRI echo images. This retrospective study evaluated 508 knee MRI volumes from 361 subjects (mean age: $40.4 \pm 12.2$ years; 179 female) across three cohorts. Ground truth segmentation masks were generated from DESS images using a pretrained model with manual correction, and $T_{1ρ}$ and $T_2$ maps were computed from magnetization-prepared angle-modulated partitioned $k$-space spoiled gradient echo snapshots (MAPSS) echo images. MT-cGAN was trained to jointly synthesize DESS-like images and segment cartilage and meniscus directly from echo images. Model performance was evaluated using Dice score for segmentation accuracy and coefficient of variation (CV) for $T_{1ρ}$ and $T_2$ quantification. MT-cGAN achieved the highest segmentation performance, mean Dice score 0.84 (range: 0.80--0.86) across all cartilage and meniscus compartments and significantly outperformed the state-of-the-art conditional GAN model with transfer learning (mean Dice, 0.82; $p < 0.001$, Wilcoxon signed-rank test). For relaxometry quantification, MT-cGAN demonstrated the highest consistency with the reference DESS protocol, yielding the lowest CV ($T_{1ρ}$: 1.84%, $T_2$: 1.81%). The proposed MT-cGAN accurately segmented cartilage and menisci while providing reliable $T_{1ρ}$ and $T_2$ quantification directly from echo images. By eliminating the need for separate morphological DESS scans, this workflow reduces required scan times to facilitate the clinical translation of qMRI.

cs.CV↗

Abnormality Detection and Localization in Chest X-Rays using Deep Convolutional Neural Networks

Chest X-Rays (CXRs) are widely used for diagnosing abnormalities in the heart and lung area. Automatically detecting these abnormalities with high accuracy could greatly enhance real world diagnosis processes. Lack of standard publicly available dataset and benchmark studies, however, makes it difficult to compare various detection methods. In order to overcome these difficulties, we have used a publicly available Indiana CXR, JSRT and Shenzhen dataset and studied the performance of known deep convolutional network (DCN) architectures on different abnormalities. We find that the same DCN architecture doesn't perform well across all abnormalities. Shallow features or earlier layers consistently provide higher detection accuracy compared to deep features. We have also found ensemble models to improve classification significantly compared to single model. Combining these insight, we report the highest accuracy on chest X-Ray abnormality detection on these datasets. We find that for cardiomegaly detection, the deep learning method improves the accuracy by a staggering 17 percentage point compared to rule based methods. We applied the techniques to the problem of tuberculosis detection on a different dataset and achieved the highest accuracy. Our localization experiments using these trained classifiers show that for spatially spread out abnormalities like cardiomegaly and pulmonary edema, the network can localize the abnormalities successfully most of the time. One remarkable result of the cardiomegaly localization is that the heart and its surrounding region is most responsible for cardiomegaly detection, in contrast to the rule based models where the ratio of heart and lung area is used as the measure. We believe that through deep learning based classification and localization, we will discover many more interesting features in medical image diagnosis that are not considered traditionally.

cs.CV↗