arXiv subjects

Aiyin Cao

Publications and source records attributed to Aiyin Cao.

2 recordsLinked to original sources

arXiv2007

Thermal Impact on Spiking Properties in Hodgkin-Huxley Neuron with Synaptic Stimulus

The effect of environmental temperature on neuronal spiking behaviors is investigated by numerically simulating the temperature dependence of spiking threshold of the Hodgkin-Huxley neuron subject to synaptic stimulus. We find that the spiking threshold exhibits a global minimum in a "comfortable temperature" range where spike initiation needs weakest synaptic strength, indicating the occurrence of optimal use of synaptic transmission in neural system. We further explore the biophysical origin of this phenomenon in ion channel gating kinetics and also discuss its possible biological relevance in information processing in neural systems.

q-bio.NC↗

arXiv2007

Theoretical Analysis of Subthreshold Oscillatory Behaviors in Nonlinear Autonomous Systems

We have developed a linearization method to investigate the subthreshold oscillatory behaviors in nonlinear autonomous systems. By considering firstly the neuronal system as an example, we show that this theoretical approach can predict quantitatively the subthreshold oscillatory activities, including the damping coefficients and the oscillatory frequencies which are in good agreement with those observed in experiments. Then we generalize the linearization method to an arbitrary autonomous nonlinear system. The detailed extension of this theoretical approach is also presented and further discussed.

q-bio.QM↗