arXiv subjects

Albert-Laszlo Barabasi

Publications and source records attributed to Albert-Laszlo Barabasi.

At least 19 recordsLinked to original sources

arXiv2025

Quantifying Institutional Gender Inequality in Contemporary Visual Art

From disparities in the number of exhibiting artists to auction opportunities, there is evidence of women's under-representation in visual art. Here we explore the exhibition history and auction sales of 65,768 contemporary artists in 20,389 institutions, revealing gender differences in the artist population, exhibitions and auctions. We distinguish between two criteria for gender equity: gender-neutrality, when artists have gender-independent access to exhibition opportunities, and gender-balanced, that strives for gender parity in representation, finding that 58\% of institutions are gender-neutral but only 24\% are gender-balanced, and that the fraction of man-overrepresented institutions increases with institutional prestige. We define artist's co-exhibition gender to capture the gender inequality of the institutions that an artist exhibits. Finally, we use logistic regression to predict an artist's access to the auction market, finding that co-exhibition gender has a stronger correlation with success than the artist's gender. These results help unveil and quantify the institutional forces that relate to the persistent gender imbalance in the art world.

cs.SI↗

arXiv2024

Human-AI Coevolution

Human-AI coevolution, defined as a process in which humans and AI algorithms continuously influence each other, increasingly characterises our society, but is understudied in artificial intelligence and complexity science literature. Recommender systems and assistants play a prominent role in human-AI coevolution, as they permeate many facets of daily life and influence human choices on online platforms. The interaction between users and AI results in a potentially endless feedback loop, wherein users' choices generate data to train AI models, which, in turn, shape subsequent user preferences. This human-AI feedback loop has peculiar characteristics compared to traditional human-machine interaction and gives rise to complex and often ``unintended'' social outcomes. This paper introduces Coevolution AI as the cornerstone for a new field of study at the intersection between AI and complexity science focused on the theoretical, empirical, and mathematical investigation of the human-AI feedback loop. In doing so, we: (i) outline the pros and cons of existing methodologies and highlight shortcomings and potential ways for capturing feedback loop mechanisms; (ii) propose a reflection at the intersection between complexity science, AI and society; (iii) provide real-world examples for different human-AI ecosystems; and (iv) illustrate challenges to the creation of such a field of study, conceptualising them at increasing levels of abstraction, i.e., technical, epistemological, legal and socio-political.

cs.AI↗

arXiv2024

Human Mobility in the Metaverse

The metaverse promises a shift in the way humans interact with each other, and with their digital and physical environments. The lack of geographical boundaries and travel costs in the metaverse prompts us to ask if the fundamental laws that govern human mobility in the physical world apply. We collected data on avatar movements, along with their network mobility extracted from NFT purchases. We find that despite the absence of commuting costs, an individuals inclination to explore new locations diminishes over time, limiting movement to a small fraction of the metaverse. We also find a lack of correlation between land prices and visitation, a deviation from the patterns characterizing the physical world. Finally, we identify the scaling laws that characterize meta mobility and show that we need to add preferential selection to the existing models to explain quantitative patterns of metaverse mobility. Our ability to predict the characteristics of the emerging meta mobility network implies that the laws governing human mobility are rooted in fundamental patterns of human dynamics, rather than the nature of space and cost of movement.

cs.SI↗

arXiv2023

iGEM: a model system for team science and innovation

Teams are a primary source of innovation in science and technology. Rather than examining the lone genius, scholarly and policy attention has shifted to understanding how team interactions produce new and useful ideas. Yet the organizational roots of innovation remain unclear, in part because of the limitations of current data. This paper introduces the international Genetically Engineered Machine (iGEM) competition, a model system for studying team science and innovation. By combining digital laboratory notebooks with performance data from 2,406 teams over multiple years of participation, we reveal shared dynamical and organizational patterns across teams and identify features associated with team performance and success. This dataset makes visible organizational behavior that is typically hidden, and thus understudied, creating new opportunities for the science of science and innovation.

cs.SI↗

arXiv2023

The Clinical Trials Puzzle: How Network Effects Limit Drug Discovery

The depth of knowledge offered by post-genomic medicine has carried the promise of new drugs, and cures for multiple diseases. To explore the degree to which this capability has materialized, we extract meta-data from 356,403 clinical trials spanning four decades, aiming to offer mechanistic insights into the innovation practices in drug discovery. We find that convention dominates over innovation, as over 96% of the recorded trials focus on previously tested drug targets, and the tested drugs target only 12% of the human interactome. If current patterns persist, it would take 170 years to target all druggable proteins. We uncover two network-based fundamental mechanisms that currently limit target discovery: preferential attachment, leading to the repeated exploration of previously targeted proteins; and local network effects, limiting exploration to proteins interacting with highly explored proteins. We build on these insights to develop a quantitative network-based model of drug discovery. We demonstrate that the model is able to accurately recreate the exploration patterns observed in clinical trials. Most importantly, we show that a network-based search strategy can widen the scope of drug discovery by guiding exploration to novel proteins that are part of under explored regions in the human interactome.

q-bio.QM↗

arXiv2022

Non-Coding RNAs Improve the Predictive Power of Network Medicine

Network Medicine has improved the mechanistic understanding of disease, offering quantitative insights into disease mechanisms, comorbidities, and novel diagnostic tools and therapeutic treatments. Yet, most network-based approaches rely on a comprehensive map of protein-protein interactions, ignoring interactions mediated by non-coding RNAs (ncRNAs). Here, we systematically combine experimentally confirmed binding interactions mediated by ncRNA with protein-protein interactions, constructing the first comprehensive network of all physical interactions in the human cell. We find that the inclusion of ncRNA, expands the number of genes in the interactome by 46% and the number of interactions by 107%, significantly enhancing our ability to identify disease modules. Indeed, we find that 132 diseases, lacked a statistically significant disease module in the protein-based interactome, but have a statistically significant disease module after inclusion of ncRNA-mediated interactions, making these diseases accessible to the tools of network medicine. We show that the inclusion of ncRNAs helps unveil disease-disease relationships that were not detectable before and expands our ability to predict comorbidity patterns between diseases. Taken together, we find that including non-coding interactions improves both the breath and the predictive accuracy of network medicine.

q-bio.MN↗

arXiv2019

Historical comparison of gender inequality in scientific careers across countries and disciplines

There is extensive, yet fragmented, evidence of gender differences in academia suggesting that women are under-represented in most scientific disciplines, publish fewer articles throughout a career, and their work acquires fewer citations. Here, we offer a comprehensive picture of longitudinal gender discrepancies in performance through a bibliometric analysis of academic careers by reconstructing the complete publication history of over 1.5 million gender-identified authors whose publishing career ended between 1955 and 2010, covering 83 countries and 13 disciplines. We find that, paradoxically, the increase of participation of women in science over the past 60 years was accompanied by an increase of gender differences in both productivity and impact. Most surprisingly though, we uncover two gender invariants, finding that men and women publish at a comparable annual rate and have equivalent career-wise impact for the same size body of work. Finally, we demonstrate that differences in dropout rates and career length explain a large portion of the reported career-wise differences in productivity and impact. This comprehensive picture of gender inequality in academia can help rephrase the conversation around the sustainability of women's careers in academia, with important consequences for institutions and policy makers.

cs.DL↗

arXiv2019

Taking census of physics

Over the past decades, the diversity of areas explored by physicists has exploded, encompassing new topics from biophysics and chemical physics to network science. However, it is unclear how these new subfields emerged from the traditional subject areas and how physicists explore them. To map out the evolution of physics subfields, here, we take an intellectual census of physics by studying physicists' careers. We use a large-scale publication data set, identify the subfields of 135,877 physicists and quantify their heterogeneous birth, growth and migration patterns among research areas. We find that the majority of physicists began their careers in only three subfields, branching out to other areas at later career stages, with different rates and transition times. Furthermore, we analyse the productivity, impact and team sizes across different subfields, finding drastic changes attributable to the recent rise in large-scale collaborations. This detailed, longitudinal census of physics can inform resource allocation policies and provide students, editors and scientists with a broader view of the field's internal dynamics.

physics.soc-ph↗

arXiv2018

Topological Phase Transitions in Spatial Networks

Most social, technological and biological networks are embedded in a finite dimensional space, and the distance between two nodes influences the likelihood that they link to each other. Indeed, in social systems, the chance that two individuals know each other drops rapidly with the distance between them; in the cell, proteins predominantly interact with proteins in the same cellular compartment; in the brain, neurons mainly link to nearby neurons. Most modeling frameworks that aim to capture the empirically observed degree distributions tend to ignore these spatial constraints. In contrast, models that account for the role of the physical distance often predict bounded degree distributions, in disagreement with the empirical data. Here we address a long-standing gap in the spatial network literature by deriving several key network characteristics of spatial networks, from the analytical form of the degree distribution to path lengths and local clustering. The mathematically exact results predict the existence of two distinct phases, each governed by a different dynamical equation, with distinct testable predictions. We use empirical data to offer direct evidence for the practical relevance of each of these phases in real networks, helping better characterize the properties of spatial networks.

physics.soc-ph↗

arXiv2018

Caenorhabditis elegans and the network control framework - FAQs

Control is essential to the functioning of any neural system. Indeed, under healthy conditions the brain must be able to continuously maintain a tight functional control between the system's inputs and outputs. One may therefore hypothesise that the brain's wiring is predetermined by the need to maintain control across multiple scales, maintaining the stability of key internal variables, and producing behaviour in response to environmental cues. Recent advances in network control have offered a powerful mathematical framework to explore the structure-function relationship in complex biological, social, and technological networks, and are beginning to yield important and precise insights for neuronal systems. The network control paradigm promises a predictive, quantitative framework to unite the distinct datasets necessary to fully describe a nervous system, and provide mechanistic explanations for the observed structure and function relationships. Here, we provide a thorough review of the network control framework as applied to C. elegans, in the style of a FAQ. We present the theoretical, computational, and experimental aspects of network control, and discuss its current capabilities and limitations, together with the next likely advances and improvements. We further present the Python code to enable exploration of control principles in a manner specific to this prototypical organism.

q-bio.NC↗

arXiv2017

Human Perception of Performance

Humans are routinely asked to evaluate the performance of other individuals, separating success from failure and affecting outcomes from science to education and sports. Yet, in many contexts, the metrics driving the human evaluation process remain unclear. Here we analyse a massive dataset capturing players' evaluations by human judges to explore human perception of performance in soccer, the world's most popular sport. We use machine learning to design an artificial judge which accurately reproduces human evaluation, allowing us to demonstrate how human observers are biased towards diverse contextual features. By investigating the structure of the artificial judge, we uncover the aspects of the players' behavior which attract the attention of human judges, demonstrating that human evaluation is based on a noticeability heuristic where only feature values far from the norm are considered to rate an individual's performance.

physics.soc-ph↗

arXiv2016

Spectrum of Controlling and Observing Complex Networks

Observing and controlling complex networks are of paramount interest for understanding complex physical, biological and technological systems. Recent studies have made important advances in identifying sensor or driver nodes, through which we can observe or control a complex system. Yet, the observational uncertainty induced by measurement noise and the energy required for control continue to be significant challenges in practical applications. Here we show that the variability of control energy and observational uncertainty for different directions of the state space depend strongly on the number of driver nodes. In particular, we find that if all nodes are directly driven, control is energetically feasible, as the maximum energy increases sublinearly with the system size. If, however, we aim to control a system through a single node, control in some directions is energetically prohibitive, increasing exponentially with the system size. For the cases in between, the maximum energy decays exponentially when the number of driver nodes increases. We validate our findings in several model and real networks, arriving to a series of fundamental laws to describe the control energy that together deepen our understanding of complex systems.

physics.soc-ph↗

arXiv2015

Identifying the structural discontinuities of human interactions

The idea of a hierarchical spatial organization of society lies at the core of seminal theories in human geography that have strongly influenced our understanding of social organization. In the same line, the recent availability of large-scale human mobility and communication data has offered novel quantitative insights hinting at a strong geographical confinement of human interactions within neighboring regions, extending to local levels within countries. However, models of human interaction largely ignore this effect. Here, we analyze several country-wide networks of telephone calls and uncover a systematic decrease of communication induced by borders which we identify as the missing variable in state-of-the-art models. Using this empirical evidence, we propose an alternative modeling framework that naturally stylize the damping effect of borders. We show that this new notion substantially improves the predictive power of widely used interaction models, thus increasing our ability to predict social activities and to plan the development of infrastructures across multiple scales.

physics.soc-ph↗

arXiv2014

Career on the Move: Geography, Stratification, and Scientific Impact

Changing institutions is an integral part of an academic life. Yet little is known about the mobility patterns of scientists at an institutional level and how these career choices affect scientific outcomes. Here, we examine over 420,000 papers, to track the affiliation information of individual scientists, allowing us to reconstruct their career trajectories over decades. We find that career movements are not only temporally and spatially localized, but also characterized by a high degree of stratification in institutional ranking. When cross-group movement occurs, we find that while going from elite to lower-rank institutions on average associates with modest decrease in scientific performance, transitioning into elite institutions does not result in subsequent performance gain. These results offer empirical evidence on institutional level career choices and movements and have potential implications for science policy.

physics.soc-ph↗

arXiv2013

Connections between Human Dynamics and Network Science

The increasing availability of large-scale data on human behavior has catalyzed simultaneous advances in network theory, capturing the scaling properties of the interactions between a large number of individuals, and human dynamics, quantifying the temporal characteristics of human activity patterns. These two areas remain disjoint, each pursuing as separate lines of inquiry. Here we report a series of generic relationships between the quantities characterizing these two areas by demonstrating that the degree and link weight distributions in social networks can be expressed in terms of the dynamical exponents characterizing human activity patterns. We test the validity of these theoretical predictions on datasets capturing various facets of human interactions, from mobile calls to tweets.

physics.soc-ph↗

arXiv2009

A dynamic network approach for the study of human phenotypes

The use of networks to integrate different genetic, proteomic, and metabolic datasets has been proposed as a viable path toward elucidating the origins of specific diseases. Here we introduce a new phenotypic database summarizing correlations obtained from the disease history of more than 30 million patients in a Phenotypic Disease Network (PDN). We present evidence that the structure of the PDN is relevant to the understanding of illness progression by showing that (1) patients develop diseases close in the network to those they already have; (2) the progression of disease along the links of the network is different for patients of different genders and ethnicities; (3) patients diagnosed with diseases which are more highly connected in the PDN tend to die sooner than those affected by less connected diseases; and (4) diseases that tend to be preceded by others in the PDN tend to be more connected than diseases that precede other illnesses, and are associated with higher degrees of mortality. Our findings show that disease progression can be represented and studied using network methods, offering the potential to enhance our understanding of the origin and evolution of human diseases. The dataset introduced here, released concurrently with this publication, represents the largest relational phenotypic resource publicly available to the research community.

physics.bio-ph↗

arXiv2008

Predicting synthetic rescues in metabolic networks

An important goal of medical research is to develop methods to recover the loss of cellular function due to mutations and other defects. Many approaches based on gene therapy aim to repair the defective gene or to insert genes with compensatory function. Here, we propose an alternative, network-based strategy that aims to restore biological function by forcing the cell to either bypass the functions affected by the defective gene, or to compensate for the lost function. Focusing on the metabolism of single-cell organisms, we computationally study mutants that lack an essential enzyme, and thus are unable to grow or have a significantly reduced growth rate. We show that several of these mutants can be turned into viable organisms through additional gene deletions that restore their growth rate. In a rather counterintuitive fashion, this is achieved via additional damage to the metabolic network. Using flux balance-based approaches, we identify a number of synthetically viable gene pairs, in which the removal of one enzyme-encoding gene results in a nonviable phenotype, while the deletion of a second enzyme-encoding gene rescues the organism. The systematic network-based identification of compensatory rescue effects may open new avenues for genetic interventions.

q-bio.MN↗

arXiv2007

Impact of non-Poisson activity patterns on spreading processes

Halting a computer or biological virus outbreak requires a detailed understanding of the timing of the interactions between susceptible and infected individuals. While current spreading models assume that users interact uniformly in time, following a Poisson process, a series of recent measurements indicate that the inter-contact time distribution is heavy tailed, corresponding to a temporally inhomogeneous bursty contact process. Here we show that the non-Poisson nature of the contact dynamics results in prevalence decay times significantly larger than predicted by the standard Poisson process based models. Our predictions are in agreement with the detailed time resolved prevalence data of computer viruses, which, according to virus bulletins, show a decay time close to a year, in contrast with the one day decay predicted by the standard Poisson process based models.

physics.data-an↗