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Alberto Dinelli

Publications and source records attributed to Alberto Dinelli.

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Unifying hydrodynamic theory for motility-regulated active matter: from single particles to interacting polymers

Understanding how microscopic motility shapes emergent collective behaviors is a challenging task in active matter, especially when self-propulsion is regulated by external cues or via quorum-sensing interactions. To address this problem, we derive a closed hydrodynamics for scalar active matter with spatially-regulated motility, under general hypotheses for the microscopic dynamics of the particles' orientations. We show that, at large scales, the contribution of the latter is entirely captured by the autocorrelation tensor of the orientations. This allows us to establish a macroscopic equivalence within a broad class of motility-regulated active systems, from single particles to active polymers. Our formalism allows us to reveal a new form of motility-induced phase separation for quorum-sensing active polymers, which we term anti-MIPS, where dense phases exhibit enhanced activity relative to dilute regions. Our theory shows that anti-MIPS generically arises for motility-regulated agents with internal structure, uncovering the existence of several distinct transition pathways.

cond-mat.stat-mech

Multiscale perturbative approach to active matter with motility regulation

We present a coarse-graining method applicable to dry scalar active matter with motility regulation. Our approach, based on a multiscale perturbative expansion of the backward Kolmogorov equation, does not rely on any specific microscopic dynamics for the particles' orientations. Its generality allows us to address different forms of motility regulation, from space-dependent self-propulsion speed to taxis, and to extend the analysis to a class of non-Markovian orientational dynamics. Furthermore, we identify general conditions on the microscopic dynamics that ensure the existence of an effective large-scale equilibrium regime. When the latter are violated, our theoretical framework is able to quantitatively capture the emergence of large-scale particle currents. We directly apply our coarse-grained theory to several models of self-propelled agents, ranging from single particles to active polymers, and test our analytical predictions with numerical simulations. Finally, we show that our theory naturally extends to active matter with density-mediated interactions, such as quorum sensing, with potential applications to self-organizing soft materials.

cond-mat.stat-mech

Active topological strings in renewing nematopolar fluids

Active matter often simultaneously exhibits different kinds of orientational order and, in many cases of biological interest, undergoes continuous material renewal. In renewing nematopolar fluids we find stable topological strings, structures consisting of two nematic point defects connected by a defect line in the polar field. We identify the mechanism underlying string stabilization and unveil how string length is determined. In the presence of active stress, we observe active-string chaos. Our work identifies continuous material renewal as a generic mechanism underlying the stabilization of topological defect structures in systems with mixed order parameters. It could be used for orchestrating living matter during development and other biological processes.

cond-mat.soft

Contact Forces in Motility-Regulated Active Matter

Long-range interactions are ubiquitous in nature, where they are mediated by diffusive fields at the cellular scale or by visual cues for groups of animals. Short-range forces, which are paradigmatic in physics, can thus often be neglected when modeling the collective behaviors of biological systems induced by mediated interactions. However, when self-organization leads to the emergence of dense phases, we show that excluded-volume interactions play an important and versatile role. We consider assemblies of active particles that undergo either condensation or phase-separation due to motility regulation and show that short-range repulsive forces can induce opposite effects. When motility regulation triggers an absorbing phase transition, such as a chemotactic collapse, repulsive forces opposes the formation of condensates and stabilize the coexistence between finite-density phases. In contrast, when motility regulation induces liquid-gas coexistence, repulsive forces can, counterintuitively, lead to a significant increase in the liquid density.

cond-mat.soft

Random motility regulation as a generic mechanism of community formation

The self-organization of microbial ecosystems involves a large variety of mechanisms, ranging from biochemical signaling to population dynamics. Among these, the role of motility regulation has been little studied, despite the importance of active migration processes. Here we show how weak, random motility regulation suffices to induce complex forms of organization in bacterial mixtures comprising a large number of coexisting strains. First, we simulate microscopic models of run-and-tumble bacteria whose self-propulsion speeds are weakly regulated by the local density of each strain, mimicking the impact of weak, random metabolic interactions. Our simulations reveal that, as the heterogeneity of the interaction network increases, the system undergoes a phase transition leading to the emergence of distinct, spatially segregated communities. To account for these results and assess their robustness, we use random-matrix theory to analyze the hydrodynamic description of the bacterial mixture, obtaining a quantitative agreement with our microscopic simulations. Our results hold for a variety of motility-regulation mechanisms and highlight the need to characterize the role of motility regulation in experimentally relevant situations.

cond-mat.stat-mech

Synthetic Quorum Sensing and Absorbing Phase Transitions in Colloidal Active Matter

Unlike biological active matter that constantly adapt to their environment, the motors of synthetic active particles are typically agnostic to their surroundings and merely operate at constant force. Here, we design colloidal active rods capable of modulating their inner activity in response to crowding, thereby enforcing a primitive form of quorum sensing interactions. Through experiments, simulations, and theory we elucidate the impact of these interactions on the phase behavior of isotropic active matter. We demonstrate that, when conditioned to density, motility regulation can either lead to an absorbing phase transition, where all particles freeze their dynamics, or to atypical phase separation, where flat interfaces supporting a net pressure drop are in mechanical equilibrium. Fully active and fully arrested particles can then form heterogeneous patterns ruled by the competition between quorum sensing and mechanical interactions. Beyond the specifics of motile colloids, we expect our findings to apply broadly to adaptive active matter assembled from living or synthetic units.

cond-mat.stat-mech

Fluctuating hydrodynamics of active particles interacting via taxis and quorum sensing: static and dynamics

In this article we derive and test the fluctuating hydrodynamic description of active particles interacting via taxis and quorum sensing, both for mono-disperse systems and for mixtures of co-existing species of active particles. We compute the average steady-state density profile in the presence of spatial motility regulation, as well as the structure factor and intermediate scattering function for interacting systems. By comparing our predictions to microscopic numerical simulations, we show that our fluctuating hydrodynamics correctly predicts the large-scale static and dynamical properties of the system. We also discuss how the theory breaks down when structures emerge at scales smaller or comparable to the persistence length of the particles. When the density field is the unique hydrodynamic mode of the system, we show that active Brownian particles, run-and-tumble particles and active Ornstein-Uhlenbeck particles, interacting via quorum-sensing or chemotactic interactions, display undistinguishable large-scale properties. This form of universality implies an interesting robustness of the predicted physics but also that large-scale observations of patterns are insufficient to assess their microscopic origins. In particular, our results predict that chemotaxis-induced and motility-induced phase separation should share strong qualitative similarities at the macroscopic scale.

cond-mat.stat-mech

Non-reciprocity across scales in active mixtures

In active matter, the lack of momentum conservation makes non-reciprocal interactions the rule rather than the exception. They lead to a rich set of emerging behaviors that are hard to account for and to predict starting from the microscopic scale, due to the absence of a generic theoretical framework out of equilibrium. Here we consider bacterial mixtures that interact via mediated, non-reciprocal interactions like quorum-sensing and chemotaxis. By explicity relating microscopic and macroscopic dynamics, we show that non-reciprocity may fade as coarse-graining proceeds, leading to large-scale bona fide equilibrium descriptions. In turns, this allows us to account quantitatively, and without fitting parameters, for the rich behaviors observed in microscopic simulations including phase separation, demixing or multi-phase coexistence. We also derive the condition under which non-reciprocity is strong enough to survive coarse-graining, leading to a wealth of dynamical patterns. Again, the explicit coarse-graining of the dynamics allows us to predict the phase diagram of the system starting from its microscopic description. All in all, our work demonstrates that the fate of non-reciprocity across scales is a subtle and important question.

cond-mat.stat-mech