arXiv subjects

Aleksandar Anžel

Publications and source records attributed to Aleksandar Anžel.

7 recordsLinked to original sources

arXiv2026

The Unified Evaluation App for DNA Data Storage Codecs

Background: Deoxyribonucleic acid (DNA) data storage is a paradigm with great potential for ultra-dense and durable information preservation. However, the rapid proliferation of coding schemes, or codecs, each with their own design constraints and reporting practices, has led to a fragmented landscape that lacks a standardized comparative assessment. Methods: We developed an open-source, modular benchmarking platform that systematically integrates and evaluates state-of-the-art DNA storage encoding and decoding methods (codecs). Our approach uses a curated, diverse set of baseline data and applies multidimensional assessment criteria that are aligned with the consensus standard of the DNA Data Storage Alliance. These criteria include encoding/decoding throughput, computational efficiency, error correction performance across substitutions, insertions, and deletions, and cost efficiency. Results: The developed platform integrates standardized wrapper functions for encoding and decoding, allows for the integration of new methods, and automates reproducible evaluations with comprehensive visual and tabular reporting. Benchmarking both contemporary and classical codecs using their default parameters and multiple metrics demonstrates that no single algorithm is optimal across all evaluated dimensions. The trade-offs between information density, success rate, runtime, and cost are quantified and shown to be critical factors in the design of future-proof formats. Conclusions: Our work establishes a rigorously standardized, open-source evaluation framework that enables reproducible benchmarking, supports evidence-based codec selection, and provides the necessary foundation for translating DNA data storage from experimental research into deployable archival systems.

cs.ET↗

arXiv2026

UbiQVision: Quantifying Uncertainty in XAI for Image Recognition

Recent advances in deep learning have led to its widespread adoption across diverse domains, including medical imaging. This progress is driven by increasingly sophisticated model architectures, such as ResNets, Vision Transformers, and Hybrid Convolutional Neural Networks, that offer enhanced performance at the cost of greater complexity. This complexity often compromises model explainability and interpretability. SHAP has emerged as a prominent method for providing interpretable visualizations that aid domain experts in understanding model predictions. However, SHAP explanations can be unstable and unreliable in the presence of epistemic and aleatoric uncertainty. In this study, we address this challenge by using Dirichlet posterior sampling and Dempster-Shafer theory to quantify the uncertainty that arises from these unstable explanations in medical imaging applications. The framework uses a belief, plausible, and fusion map approach alongside statistical quantitative analysis to produce quantification of uncertainty in SHAP. Furthermore, we evaluated our framework on three medical imaging datasets with varying class distributions, image qualities, and modality types which introduces noise due to varying image resolutions and modality-specific aspect covering the examples from pathology, ophthalmology, and radiology, introducing significant epistemic uncertainty.

cs.CV↗

arXiv2026

A Multi-Technique Approach for Improving Summary Polar Diagrams

While the polar system may lack the universal familiarity of its Cartesian counterpart, it remains indispensable for certain tasks. Summary polar diagrams, such as Taylor and mutual information diagrams, address tasks like discovering relationships, visualizing data similarity, and quantifying correspondence. Although these diagrams are invaluable tools for uncovering data relationships, their polar nature can hinder intuitiveness and lead to issues like overplotting. We present a hybrid approach that combines overview+detail, aggregation, interactive filtering, Cartesian linking, and small multiples to enhance the clarity, comprehensiveness, and functionality of summary polar diagrams. We performed a user study to assess this approach's effectiveness, noting comparable response times among participants. Additionally, three domain experts with varying visualization experience reviewed an implemented solution applying summary polar diagrams to climate, data science (novel), and machine learning, refining the approach prior to the user study. The findings underscore the versatility of our approach in enhancing comprehension, accessibility, and utility.

cs.HC↗

arXiv2026

UbiQTree: Uncertainty Quantification in XAI with Tree Ensembles

Explainable Artificial Intelligence (XAI) techniques, such as SHapley Additive exPlanations (SHAP), have become essential tools for interpreting complex ensemble tree-based models, especially in high-stakes domains such as healthcare analytics. However, SHAP values are usually treated as point estimates, which disregards the inherent and ubiquitous uncertainty in predictive models and data. This uncertainty has two primary sources: aleatoric and epistemic. The aleatoric uncertainty, which reflects the irreducible noise in the data. The epistemic uncertainty, which arises from a lack of data. In this work, we propose an approach for decomposing uncertainty in SHAP values into aleatoric, epistemic, and entanglement components. This approach integrates Dempster-Shafer evidence theory and hypothesis sampling via Dirichlet processes over tree ensembles. We validate the method across three real-world use cases with descriptive statistical analyses that provide insight into the nature of epistemic uncertainty embedded in SHAP explanations. The experimentations enable to provide more comprehensive understanding of the reliability and interpretability of SHAP-based attributions. This understanding can guide the development of robust decision-making processes and the refinement of models in high-stakes applications. Through our experiments with multiple datasets, we concluded that features with the highest SHAP values are not necessarily the most stable. This epistemic uncertainty can be reduced through better, more representative data and following appropriate or case-desired model development techniques. Tree-based models, especially bagging, facilitate the effective quantification of epistemic uncertainty.

cs.AI↗

arXiv2025

The Open Syndrome Definition

Case definitions are essential for effectively communicating public health threats. However, the absence of a standardized, machine-readable format poses significant challenges to interoperability, epidemiological research, the exchange of qualitative data, and the effective application of computational analysis methods, including artificial intelligence (AI). This complicates comparisons and collaborations across organizations and regions, limits data integration, and hinders technological innovation in public health. To address these issues, we propose the first open, machine-readable format for representing case and syndrome definitions. Additionally, we introduce the first comprehensive dataset of standardized case definitions and tools to convert existing human-readable definitions into machine-readable formats. We also provide an accessible online platform for browsing, analyzing, and contributing new definitions, available at https://opensyndrome.org. The Open Syndrome Definition format enables consistent, scalable use of case definitions across systems, unlocking AI's potential to strengthen public health preparedness and response. The source code for the format can be found at https://github.com/OpenSyndrome/schema under the MIT license.

cs.AI↗

arXiv2025

Surrogate Interpretable Graph for Random Decision Forests

The field of health informatics has been profoundly influenced by the development of random forest models, which have led to significant advances in the interpretability of feature interactions. These models are characterized by their robustness to overfitting and parallelization, making them particularly useful in this domain. However, the increasing number of features and estimators in random forests can prevent domain experts from accurately interpreting global feature interactions, thereby compromising trust and regulatory compliance. A method called the surrogate interpretability graph has been developed to address this issue. It uses graphs and mixed-integer linear programming to analyze and visualize feature interactions. This improves their interpretability by visualizing the feature usage per decision-feature-interaction table and the most dominant hierarchical decision feature interactions for predictions. The implementation of a surrogate interpretable graph enhances global interpretability, which is critical for such a high-stakes domain.

cs.LG↗

arXiv2024

Kernel-based Learning for Safe Control of Discrete-Time Unknown Systems under Incomplete Observations

Safe control for dynamical systems is critical, yet the presence of unknown dynamics poses significant challenges. In this paper, we present a learning-based control approach for tracking control of a class of high-order systems, operating under the constraint of partially observable states. The uncertainties inherent within the systems are modeled by kernel ridge regression, leveraging the proposed strategic data acquisition approach with limited state measurements. To achieve accurate trajectory tracking, a state observer that seamlessly integrates with the control law is devised. The analysis of the guaranteed control performance is conducted using Lyapunov theory due to the deterministic prediction error bound of kernel ridge regression, ensuring the adaptability of the approach in safety-critical scenarios. To demonstrate the effectiveness of our proposed approach, numerical simulations are performed, underscoring its contributions to the advancement of control strategies.

eess.SY↗