arXiv subjects

Aleksander Gajos

Publications and source records attributed to Aleksander Gajos.

13 recordsLinked to original sources

arXiv2025

Realistic Total-Body J-PET Geometry Optimization -- Monte Carlo Study

Total-Body PET is one of the most promising medical diagnostics modalities. The high sensitivity provided by Total-Body technology can be advantageous for novel tomography methods like positronium imaging. Several efforts are ongoing to lower the price of the TB-PET systems. Among the alternatives, the Jagiellonian PET (J-PET) technology, based on plastic scintillator strips, offers a low-cost alternative. The work aimed to compare five Total-Body J-PET geometries as a possible next generation J-PET scanner design. We present comparative studies of performance characteristics of the cost-effective Total-Body PET scanners using J-PET technology. We investigated in silico five Total-Body scanner geometries. Monte Carlo simulations of the XCAT phantom, the 2-meter sensitivity line source and positronium sensitivity phantoms were performed. We compared the sensitivity profiles for 2-gamma and 3-gamma tomography, relative cost of the setups and performed quantitative analysis of the reconstructed images. The analysis of the reconstructed XCAT images reveals the superiority of the seven-ring scanners over the three-ring setups. However, the three-ring scanners would be approximately 2-3 times cheaper. The peak sensitivity values for two-gamma vary from 20 to 34 cps/kBq. The sensitivity curves for the positronium tomography have a similar shape to the two-gamma sensitivity profiles. The peak values are lower compared to the two-gamma cases, from about 20-28 times, with a maximum of 1.66 cps/kBq. The results show the feasibility of multi-organ imaging of all the systems to be considered for the next generation of TB J-PET designs. The relative cost for all the scanners is about 10-4 times lower compared to the cost of the uExplorer. These properties coupled together with J-PET cost-effectiveness, make the J-PET technology an attractive solution for broad application in clinics.

physics.med-ph↗

arXiv2024

Discrete symmetries tested at 10$^{-4}$ precision using linear polarization of photons from positronium annihilations

Discrete symmetries play an important role in particle physics with violation of CP connected to the matter-antimatter imbalance in the Universe. We report the most precise test of P, T and CP invariance in decays of ortho-positronium, performed with methodology involving polarization of photons from these decays. Positronium, the simplest bound state of an electron and positron, is of recent interest with discrepancies reported between measured hyperfine energy structure and theory at the level of $10^{-4}$ signaling a need for better understanding of the positronium system at this level. We test discrete symmetries using photon polarizations determined via Compton scattering in the dedicated J-PET tomograph on an event-by-event basis and without the need to control the spin of the positronium with an external magnetic field, in contrast to previous experiments. Our result is consistent with QED expectations at the level of 0.0007 and one standard deviation.

hep-ph↗

arXiv2023

Comparative studies of the sensitivities of sparse and full geometries of Total-Body PET scanners built from crystals and plastic scintillators

Background: Total-Body imaging offers high sensitivity, single-bed position, and low dose, but high construction costs limit worldwide utilization. This study compares existing and developing tomographs using plastic scintillators via simulations to propose a cost-efficient Total-Body PET scanner. Methods: Simulations of eight uEXPLORER tomographs with different scintillator materials, axial field-of-view, and detector configuration, and eight J-PET scanners with various field-of-view, plastic scintillator cross-sections, and layers were performed. Biograph Vision was also simulated. Two types of simulations were conducted with a central source and a water-filled phantom. Results: BGO crystal-based scanners showed the best sensitivity (350 cps/kBq at the center). Sparse geometry or LYSO crystals reduced sensitivity. J-PET design showed similar sensitivity to sparse LYSO detectors, with full body coverage and additional gain for brain imaging. Conclusion: The J-PET tomography system using plastic scintillators could be a cost-efficient alternative for Total-Body PET scanners, overcoming high construction costs while maintaining sensitivity

physics.med-ph↗

arXiv2023

Modular J-PET with Improved o-Ps Detection Efficiency for CPT Tests

J-PET is a photon detector built of plastic scintillators, which already has been commissioned for CPT studies in the decays of positronium. In the first experiment, J-PET has achieved a sensitivity to CPT violation at a level of 10^{-4}, and now it aims to reach a level of 10^{-5}. This will be done by enhancing the three-photon registration efficiency for ortho-positronium decays using a new layer of densely packed plastic scintillators termed Modular J-PET. We present the simulation studies performed for different experimental detection setups to be used for the next CPT test with the Modular J-PET detector.

hep-ph↗

arXiv2021

Positronium imaging with the novel multiphoton PET scanner

In vivo assessment of cancer and precise location of altered tissues at initial stages of molecular disorders are important diagnostic challenges. Positronium is copiously formed in the free molecular spaces in the patient's body during positron emission tomography (PET). The positronium properties vary according to the size of inter- and intramolecular voids and the concentration of molecules in them such as, e.g., molecular oxygen, O2; therefore, positronium imaging may provide information about disease progression during the initial stages of molecular alterations. Current PET systems do not allow acquisition of positronium images. This study presents a new method that enables positronium imaging by simultaneous registration of annihilation photons and deexcitation photons from pharmaceuticals labeled with radionuclides. The first positronium imaging of a phantom built from cardiac myxoma and adipose tissue is demonstrated. It is anticipated that positronium imaging will substantially enhance the specificity of PET diagnostics.

physics.med-ph↗

arXiv2021

Testing CPT symmetry in ortho-positronium decays with positronium annihilation tomography

Charged lepton system symmetry under combined charge, parity, and time-reversal transformation (CPT) remains scarcely tested. Despite stringent quantum-electrodynamic limits, discrepancies in predictions for the electron-positron bound state (positronium atom) motivate further investigation, including fundamental symmetry tests. While CPT noninvariance effects could be manifested in non-vanishing angular correlations between final-state photons and spin of annihilating positronium, measurements were previously limited by knowledge of the latter. Here, we demonstrate tomographic reconstruction techniques applied to three-photon annihilations of ortho-positronium atoms to estimate their spin polarisation without magnetic field or polarised positronium source. We use a plastic-scintillator-based positron-emission-tomography scanner to record ortho-positronium (o-Ps) annihilations with single-event estimation of o-Ps spin and determine the complete spectrum of an angular correlation operator sensitive to CPT-violating effects. We find no violation at the precision level of 10^{-4}, with an over threefold improvement on the previous measurement.

nucl-ex↗

arXiv2021

Simulating NEMA characteristics of the modular total-body J-PET scanner -- an economic total-body PET from plastic scintillators

The purpose of the presented research is estimation of the performance characteristics of the economic Total-Body Jagiellonian-PET system (TB-J-PET) constructed from plastic scintillators. The characteristics are estimated according to the NEMA NU-2-2018 standards utilizing the GATE package. The simulated detector consists of 24 modules, each built out of 32 plastic scintillator strips (each with cross section of 6 mm times 30 mm and length of 140 cm or 200 cm) arranged in two layers in regular 24-sided polygon circumscribing a circle with the diameter of 78.6 cm. For the TB-J-PET with an axial field-of-view (AFOV) of 200 cm, a spatial resolutions of 3.7 mm (transversal) and 4.9 mm (axial) are achieved. The NECR peak of 630 kcps is expected at 30 kBq/cc activity concentration and the sensitivity at the center amounts to 38 cps/kBq. The SF is estimated to 36.2 %. The values of SF and spatial resolution are comparable to those obtained for the state-of-the-art clinical PET scanners and the first total-body tomographs: uExplorer and PennPET. With respect to the standard PET systems with AFOV in the range from 16 cm to 26 cm, the TB-J-PET is characterized by an increase in NECR approximately by factor of 4 and by the increase of the whole-body sensitivity by factor of 12.6 to 38. The TOF resolution for the TB-J-PET is expected to be at the level of CRT=240 ps (FWHM). For the TB-J-PET with an axial field-of-view (AFOV) of 140 cm, an image quality of the reconstructed images of a NEMA IEC phantom was presented with a contrast recovery coefficient (CRC) and a background variability parameters. The increase of the whole-body sensitivity and NECR estimated for the TB-J-PET with respect to current commercial PET systems makes the TB-J-PET a promising cost-effective solution for the broad clinical applications of total-body PET scanners.

physics.ins-det↗

arXiv2020

Sensitivity of discrete symmetry tests in the positronium system with the J-PET detector

Study of certain angular correlations in the three-photon annihilations of the triplet state of positronium, the electron-positron bound state, may be used as a probe of potential CP and CPT-violating effects in the leptonic sector. We present the perspectives of CP and CPT tests using this process recorded with a novel detection system for photons in the positron annihilation energy range, the Jagiellonian PET (J-PET). We demonstrate the capability of this system to register three-photon annihilations with an unprecedented range of kinematical configurations and to measure the CPT-odd correlation between positronium spin and annihilation plane orientation with a precision improved by at least an order of magnitude with respect to present results. We also discuss the the means to control and reduce detector asymmetries in order to allow J-PET to set the first measurement of the correlation between positronium spin and momentum of the most energetic annihilation photon which has never been studied to date.

physics.ins-det↗

arXiv2020

J-PET Framework: Software platform for PET tomography data reconstruction and analysis

J-PET Framework is an open-source software platform for data analysis, written in C++ and based on the ROOT package. It provides a common environment for implementation of reconstruction, calibration and filtering procedures, as well as for user-level analyses of Positron Emission Tomography data. The library contains a set of building blocks that can be combined by users with even little programming experience, into chains of processing tasks through a convenient, simple and well-documented API. The generic input-output interface allows processing the data from various sources: low-level data from the tomography acquisition system or from diagnostic setups such as digital oscilloscopes, as well as high-level tomography structures e.g. sinograms or a list of lines-of-response. Moreover, the environment can be interfaced with Monte Carlo simulation packages such as GEANT and GATE, which are commonly used in the medical scientific community.

physics.ins-det↗

arXiv2018

Estimating the NEMA characteristics of the J-PET tomograph using the GATE package

The novel whole-body PET system based on plastic scintillators is developed by the {J-PET} Collaboration. It consists of plastic scintillator strips arranged axially in the form of a cylinder, allowing the cost-effective construction of the total-body PET. In order to determine properties of the scanner prototype and optimize its geometry, advanced computer simulations using the GATE software were performed. The spatial resolution, the sensitivity, the scatter fraction and the noise equivalent count rate were estimated according to the NEMA norm as a function of the length of the tomograph, number of the detection layers, diameter of the tomographic chamber and for various types of the applied readout. For the single-layer geometry with the diameter of 85 cm, strip length of 100 cm, cross-section of 4 mm x 20 mm and silicon photomultipliers with the additional layer of wavelength shifter as the readout, the spatial resolution (FWHM) in the centre of the scanner is equal to 3 mm (radial, tangential) and 6 mm (axial). For the analogous double-layer geometry with the same readout, diameter and scintillator length, with the strip cross-section of 7 mm x 20 mm, the NECR peak of 300 kcps was reached at 40 kBq/cc activity concentration, the scatter fraction is estimated to about 35% and the sensitivity at the centre amounts to 14.9 cps/kBq. Sensitivity profiles were also determined.

physics.ins-det↗

arXiv2018

Investigations of fundamental symmetries with the electron-positron systems

This work concerned two experimental searches for the violation of fundamental discrete symmetries in physical systems originating from electron-positron interactions. The first study was a direct test of the symmetry under reversal in time in transitions of neutral K mesons, performed with quantum-entangled neutral kaon pairs. Data collected by the KLOE experiment operating at the DAFNE collider in 2004-2005 were studied to select events of the KsKl->pi e nu 3pi0 and KsKl->pi+pi- pi e nu processes and compare their rates. Rates of each process identified by two time-ordered neutral kaon decays, determined as a function of a difference between kaon decays, were used to measure the asymptotic level of two T-violation sensitive ratios of double kaon decay rates, yielding the values of R2=1.020+/-0.017stat+/-0.035syst and R4=0.990+/-0.017stat+/-0.039syst. Although these results do not reach the sensitivity needed to probe T violation, this measurement proves the required reconstruction and analysis of the data is feasible and prospects exist for a statistically significant T test with a larger dataset collected by the KLOE-2 experiment if certain systematic effects are eliminated. The second part of this work comprised a demonstration of feasibility of using the J-PET detector to search for non-vanishing angular correlations in the decays of ortho-positronium atoms. Feasibility of identification of 3gamma events as well as reconstruction of their origin points using a dedicated trilateration-based method was demonstrated using MC simulations and a test measurement performed with the J-PET detector.

hep-ex↗

arXiv2017

Tests of discrete symmetries and quantum coherence with neutral kaons at the KLOE-2 experiment

The KLOE-2 detector records decays of quantum-entangled pairs of neutral kaons produced in decays of phi mesons provided by the DAFNE accelerator at the Laboratori Nazionali di Frascati, Italy. This system allows for a broad range of studies of fundamental discrete symmetries including tests which are only feasible with entangled neutral mesons. This work reports on the Lorentz non-invariance and CPT violation searches with the KSKL->pi+pi-pi+pi- process in the framework of the Standard Model Extension. Moreover, status and results of quantum coherence tests with the same process are discussed. Finally, the status of ongoing direct tests of T and CPT in neutral kaon transitions is presented. For each of thereported studies, perspectives are discussed for the KLOE-2 experiment, which is presently taking data.

hep-ex↗

arXiv2015

Study of the $K_SK_L\toπ\ellν3 π^0$ process for time reversal symmetry test at KLOE-2

This work presents prospects for conducting a novel direct test of time-reversal symmetry at the KLOE-2 experiment. Quantum entanglement of neutral K meson pairs uniquely available at KLOE-2 allows to probe directly the time-reversal symmetry (T) independently of CP violation. This is achieved by a comparison of probabilities for a transition between flavour and CP-definite states and its inverse obtained through exchange of initial and final states. As such a test requires the reconstruction of the $K_L\to 3π^0$ decay accompanied by $K_S\toπ^{\pm}\ell^{\mp}ν$ with good timing information, a new reconstruction method for this process is also presented which is capable of reconstructing the $K_L\to 3π^0$ decay with decay time resolution of O(1$τ_S$).

hep-ex↗