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Aleksei Shpilman

Publications and source records attributed to Aleksei Shpilman.

25 records · Page 2Linked to original sources

Deep Learning of Cell Classification using Microscope Images of Intracellular Microtubule Networks

Microtubule networks (MTs) are a component of a cell that may indicate the presence of various chemical compounds and can be used to recognize properties such as treatment resistance. Therefore, the classification of MT images is of great relevance for cell diagnostics. Human experts find it particularly difficult to recognize the levels of chemical compound exposure of a cell. Improving the accuracy with automated techniques would have a significant impact on cell therapy. In this paper we present the application of Deep Learning to MT image classification and evaluate it on a large MT image dataset of animal cells with three degrees of exposure to a chemical agent. The results demonstrate that the learned deep network performs on par or better at the corresponding cell classification task than human experts. Specifically, we show that the task of recognizing different levels of chemical agent exposure can be handled significantly better by the neural network than by human experts.

eess.IV↗

A comparative evaluation of machine learning methods for robot navigation through human crowds

Robot navigation through crowds poses a difficult challenge to AI systems, since the methods should result in fast and efficient movement but at the same time are not allowed to compromise safety. Most approaches to date were focused on the combination of pathfinding algorithms with machine learning for pedestrian walking prediction. More recently, reinforcement learning techniques have been proposed in the research literature. In this paper, we perform a comparative evaluation of pathfinding/prediction and reinforcement learning approaches on a crowd movement dataset collected from surveillance videos taken at Grand Central Station in New York. The results demonstrate the strong superiority of state-of-the-art reinforcement learning approaches over pathfinding with state-of-the-art behaviour prediction techniques.

cs.RO↗

Lipophilicity Prediction with Multitask Learning and Molecular Substructures Representation

Lipophilicity is one of the factors determining the permeability of the cell membrane to a drug molecule. Hence, accurate lipophilicity prediction is an essential step in the development of new drugs. In this paper, we introduce a novel approach to encoding additional graph information by extracting molecular substructures. By adding a set of generalized atomic features of these substructures to an established Direct Message Passing Neural Network (D-MPNN) we were able to achieve a new state-of-the-art result at the task of prediction of two main lipophilicity coefficients, namely logP and logD descriptors. We further improve our approach by employing a multitask approach to predict logP and logD values simultaneously. Additionally, we present a study of the model performance on symmetric and asymmetric molecules, that may yield insight for further research.

cs.LG↗

Automatic generation of reviews of scientific papers

With an ever-increasing number of scientific papers published each year, it becomes more difficult for researchers to explore a field that they are not closely familiar with already. This greatly inhibits the potential for cross-disciplinary research. A traditional introduction into an area may come in the form of a review paper. However, not all areas and sub-areas have a current review. In this paper, we present a method for the automatic generation of a review paper corresponding to a user-defined query. This method consists of two main parts. The first part identifies key papers in the area by their bibliometric parameters, such as a graph of co-citations. The second stage uses a BERT based architecture that we train on existing reviews for extractive summarization of these key papers. We describe the general pipeline of our method and some implementation details and present both automatic and expert evaluations on the PubMed dataset.

cs.LG↗

Imitation Learning Approach for AI Driving Olympics Trained on Real-world and Simulation Data Simultaneously

In this paper, we describe our winning approach to solving the Lane Following Challenge at the AI Driving Olympics Competition through imitation learning on a mixed set of simulation and real-world data. AI Driving Olympics is a two-stage competition: at stage one, algorithms compete in a simulated environment with the best ones advancing to a real-world final. One of the main problems that participants encounter during the competition is that algorithms trained for the best performance in simulated environments do not hold up in a real-world environment and vice versa. Classic control algorithms also do not translate well between tasks since most of them have to be tuned to specific driving conditions such as lighting, road type, camera position, etc. To overcome this problem, we employed the imitation learning algorithm and trained it on a dataset collected from sources both from simulation and real-world, forcing our model to perform equally well in all environments.

cs.LG↗

Artificial Intelligence for Prosthetics - challenge solutions

In the NeurIPS 2018 Artificial Intelligence for Prosthetics challenge, participants were tasked with building a controller for a musculoskeletal model with a goal of matching a given time-varying velocity vector. Top participants were invited to describe their algorithms. In this work, we describe the challenge and present thirteen solutions that used deep reinforcement learning approaches. Many solutions use similar relaxations and heuristics, such as reward shaping, frame skipping, discretization of the action space, symmetry, and policy blending. However, each team implemented different modifications of the known algorithms by, for example, dividing the task into subtasks, learning low-level control, or by incorporating expert knowledge and using imitation learning.

cs.LG↗

Deep Multi-Agent Reinforcement Learning with Relevance Graphs

Over recent years, deep reinforcement learning has shown strong successes in complex single-agent tasks, and more recently this approach has also been applied to multi-agent domains. In this paper, we propose a novel approach, called MAGnet, to multi-agent reinforcement learning (MARL) that utilizes a relevance graph representation of the environment obtained by a self-attention mechanism, and a message-generation technique inspired by the NerveNet architecture. We applied our MAGnet approach to the Pommerman game and the results show that it significantly outperforms state-of-the-art MARL solutions, including DQN, MADDPG, and MCTS.

cs.MA↗