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Alessia Gentili

Publications and source records attributed to Alessia Gentili.

3 recordsLinked to original sources

Anomalous Dynamics of Superparamagnetic Colloidal Microrobots with Tailored Statistics

Living organisms have developed advanced motion strategies for efficient space exploration, serving as inspiration for the movements of microrobots. These real-life strategies often involve anomalous dynamics displaying random movement patterns that deviate from Brownian motion. Despite their biological inspiration, autonomous stochastic navigation strategies of current microrobots remain much less versatile than those of their living counterparts. Supported by theoretical reasoning, this work demonstrates superparamagnetic colloidal microrobots with fully customizable stochastic dynamics displaying the entire spectrum of anomalous diffusion, from subdiffusion to superdiffusion, across statistically significant spatial and temporal scales (covering at least two decades). By simultaneously tuning microrobots' step-length distribution and, critically, their velocity autocorrelation function with magnetic fields, fundamental anomalous dynamics are reproduced with tailored properties mimicking Lévy walks and fractional Brownian motion. These findings pave the way for programmable microrobotic systems that replicate optimal stochastic navigation strategies found in nature for applications in medical robotics and environmental remediation.

cond-mat.soft

Objective comparison of methods to decode anomalous diffusion

Deviations from Brownian motion leading to anomalous diffusion are found in transport dynamics from quantum physics to life sciences. The characterization of anomalous diffusion from the measurement of an individual trajectory is a challenging task, which traditionally relies on calculating the trajectory mean squared displacement. However, this approach breaks down for cases of practical interest, e.g., short or noisy trajectories, heterogeneous behaviour, or non-ergodic processes. Recently, several new approaches have been proposed, mostly building on the ongoing machine-learning revolution. To perform an objective comparison of methods, we gathered the community and organized an open competition, the Anomalous Diffusion challenge (AnDi). Participating teams applied their algorithms to a commonly-defined dataset including diverse conditions. Although no single method performed best across all scenarios, machine-learning-based approaches achieved superior performance for all tasks. The discussion of the challenge results provides practical advice for users and a benchmark for developers.

physics.data-an

Characterization of anomalous diffusion classical statistics powered by deep learning (CONDOR)

Diffusion processes are important in several physical, chemical, biological and human phenomena. Examples include molecular encounters in reactions, cellular signalling, the foraging of animals, the spread of diseases, as well as trends in financial markets and climate records. Deviations from Brownian diffusion, known as anomalous diffusion, can often be observed in these processes, when the growth of the mean square displacement in time is not linear. An ever-increasing number of methods has thus appeared to characterize anomalous diffusion trajectories based on classical statistics or machine learning approaches. Yet, characterization of anomalous diffusion remains challenging to date as testified by the launch of the Anomalous Diffusion (AnDi) Challenge in March 2020 to assess and compare new and pre-existing methods on three different aspects of the problem: the inference of the anomalous diffusion exponent, the classification of the diffusion model, and the segmentation of trajectories. Here, we introduce a novel method (CONDOR) which combines feature engineering based on classical statistics with supervised deep learning to efficiently identify the underlying anomalous diffusion model with high accuracy and infer its exponent with a small mean absolute error in single 1D, 2D and 3D trajectories corrupted by localization noise. Finally, we extend our method to the segmentation of trajectories where the diffusion model and/or its anomalous exponent vary in time.

physics.data-an