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Alessio Cargioli

Publications and source records attributed to Alessio Cargioli.

5 recordsLinked to original sources

Infrared photonics for healthcare: A roadmap for proactive and predictive health management

The field of infrared (IR) photonics is currently undergoing remarkable progress, moving rapidly towards practical sensing applications demanded by medical therapy and diagnostics (theranostics). The Developments can be divided into three main categories: (i) novel devices and measurement concepts including advanced updates of classical approaches that push medical sensing into the spotlight; (ii) new demonstrations of photonic integrated circuit (PIC-)based IR devices enabling highly miniaturized sensors for point-of-care application as well as medical and wellness wearables; and (iii) technologically-mature IR demonstrators that enable first medical sensing and treatment applications. This roadmap paper provides a consolidated overview of this highly dynamic and interdisciplinary research field with a focus on the major roadblocks that limit the widespread adoption of IR photonics in large-scale medical diagnostics. Special attention is given to the ambivalence between the molecular-level spectroscopic interpretation and a broader health-state assessment, highlighting the need for a common framework. Additionally, the paper discusses the critical importance of unified measurement standards, calibration protocols, and medical certification processes to ensure the validity of experimental results, reproducibility, and clinical trust, particularly when novel experimental techniques and AI algorithms are involved. Perspectives from major past and current contributors to application-oriented IR photonics will be provided.

physics.app-ph

Epitaxial growth optimization, measurement and theoretical analysis of strain-compensated QCL grown on (511)A InP

Interface roughness scattering is an important limiting factor for achieving high performance Quantum Cascade Lasers. Following recent results, we study the growth conditions for a strain-compensated QCL emitting around 4.6 {\mu}m grown on a (511)A InP substrate using AFM and XRD measurements. We find that modulating the arsenic flux and correctly tailoring the III/V ratio is fundamental to achieve a good quality material. We report the first lasing device on such a platform with a current density threshold of 1.34 kA/cm2 and a slope efficiency of 1.1 W/A, which result suboptimal compared to the (100) reference. Finally, we find a 7% redshift of the (511)A spectrum which we attribute to an impurity scattering due to the increased incorporation along the exposed (111) direction. We validate this statement by verifying that the change in CBO and effective electron mass due to strain along a non-trivial direction cannot cause such a shift by using the k-p method generalized to arbitrary growth directions

physics.app-ph

Metasurface-Enhanced Mid-Infrared Imaging Spectroscopy with Broadband Quantum Cascade Lasers

Mid-infrared (mid-IR) spectroscopy offers unparalleled opportunities in sensing through chemically specific detection of molecular absorption fingerprints. Yet, its practical applications are limited by the weak light-matter interaction in the mid-IR range and low brightness of mid-IR light sources. Surface-enhanced infrared absorption (SEIRA) spectroscopy addresses the sensitivity limitations by leveraging resonant photonic structures, in particular, plasmonic and frequency-selective dielectric metasurfaces. However, current implementations of SEIRA approach mainly rely on complex instruments and scanning components such as Fourier-transform infrared spectroscopy and tunable external cavity quantum cascade lasers (EC QCLs). Here, we present a compact and high-throughput imaging-based SEIRA platform that combines broadband gradient metasurfaces with a radiofrequency-modulated QCL that generates remarkably broad instantaneous emission spectrum (250 cm$^{-1}$) covering absorption bands of multiple distinct molecular vibrational modes. By matching the resonance spectrum of the compact (1 mm$^2$) broadband gradient metasurface with the laser emission projected on its surface through a dispersive element, we ensure that every QCL spectral component is uniquely addressed for an efficient targeted enhancement of the electromagnetic field. This enables us to use a low-cost and room-temperature mid-IR camera, acquiring in a single frame the enhanced absorption signatures of analytes deposited on the metasurface as a barcode image, thus reducing the acquisition time by up to 3 orders of magnitude compared to the FTIR and EC QCL based measurements. Eliminating the need for tunable light sources, bulky spectrometers, and expensive low-temperature detectors, our approach enables high-throughput, miniaturized, and highly specific molecular diagnostics for diverse chemical and biological applications.

physics.optics

Quantum Walk Comb in a Dual Waveguide Quantum Cascade Laser

Ring quantum cascade lasers (QCLs) proved to be a versatile tool for generating tunable and stable frequency combs in the mid infrared range in the form of quantum walk combs. By homogeneously integrating a racetrack QCL with a passive waveguide, which lays on top of the active region plane and therefore can be designed to be fully independent from the laser geometry, we improve the light outcoupling from the ring by more than 2 orders of magnitude reaching a maximum output power of 120 mW. In addition, we show that it is possible to achieve quantum walk comb operation in the devices under analysis. Finally, we prove that we can change the light dispersion by tuning the parameters of the passive waveguide, with a direct impact on the behavior of the generated comb.

quant-ph

Quantum Cascade Lasers as Broadband Sources via Strong RF Modulation

In this work, we demonstrate that in a regime of strong modulation, by generating pulses of the length of the order of a few cavity lifetimes (hundreds of ps), a broadband quantum cascade laser can be driven to lase on a bandwidth (250cm-1) limited by the gain. In addition, the amplitude noise of the radiation was shown to be limited by the detector. A laser linewidth study has been performed under different operating conditions finding values spanning from 20MHz to 800MHz, indicating a trade-off between emission bandwidth, amplitude stability and coherence.

physics.optics