arXiv subjects

Alexander Wong

Publications and source records attributed to Alexander Wong.

At least 235 records · Page 13Linked to original sources

arXiv2016

Deep Quality: A Deep No-reference Quality Assessment System

Image quality assessment (IQA) continues to garner great interest in the research community, particularly given the tremendous rise in consumer video capture and streaming. Despite significant research effort in IQA in the past few decades, the area of no-reference image quality assessment remains a great challenge and is largely unsolved. In this paper, we propose a novel no-reference image quality assessment system called Deep Quality, which leverages the power of deep learning to model the complex relationship between visual content and the perceived quality. Deep Quality consists of a novel multi-scale deep convolutional neural network, trained to learn to assess image quality based on training samples consisting of different distortions and degradations such as blur, Gaussian noise, and compression artifacts. Preliminary results using the CSIQ benchmark image quality dataset showed that Deep Quality was able to achieve strong quality prediction performance (89% patch-level and 98% image-level prediction accuracy), being able to achieve similar performance as full-reference IQA methods.

cs.MM↗

arXiv2016

Resolution- and throughput-enhanced spectroscopy using high-throughput computational slit

There exists a fundamental tradeoff between spectral resolution and the efficiency or throughput for all optical spectrometers. The primary factors affecting the spectral resolution and throughput of an optical spectrometer are the size of the entrance aperture and the optical power of the focusing element. Thus far collective optimization of the above mentioned has proven difficult. Here, we introduce the concept of high-throughput computational slits (HTCS), a numerical technique for improving both the effective spectral resolution and efficiency of a spectrometer. The proposed HTCS approach was experimentally validated using an optical spectrometer configured with a 200 um entrance aperture, test, and a 50 um entrance aperture, control, demonstrating improvements in spectral resolution of the spectrum by ~ 50% over the control spectral resolution and improvements in efficiency of > 2 times over the efficiency of the largest entrance aperture used in the study while producing highly accurate spectra.

physics.optics↗

arXiv2016

Spatial probabilistic pulsatility model for enhancing photoplethysmographic imaging systems

Photolethysmographic imaging (PPGI) is a widefield non-contact biophotonic technology able to remotely monitor cardiovascular function over anatomical areas. Though spatial context can provide increased physiological insight, existing PPGI systems rely on coarse spatial averaging with no anatomical priors for assessing arterial pulsatility. Here, we developed a continuous probabilistic pulsatility model for importance-weighted blood pulse waveform extraction. Using a data-driven approach, the model was constructed using a 23 participant sample with large demographic variation (11/12 female/male, age 11-60 years, BMI 16.4-35.1 kg$\cdot$m$^{-2}$). Using time-synchronized ground-truth waveforms, spatial correlation priors were computed and projected into a co-aligned importance-weighted Cartesian space. A modified Parzen-Rosenblatt kernel density estimation method was used to compute the continuous resolution-agnostic probabilistic pulsatility model. The model identified locations that consistently exhibited pulsatility across the sample. Blood pulse waveform signals extracted with the model exhibited significantly stronger temporal correlation ($W=35,p<0.01$) and spectral SNR ($W=31,p<0.01$) compared to uniform spatial averaging. Heart rate estimation was in strong agreement with true heart rate ($r^2=0.9619$, error $(μ,σ)=(0.52,1.69)$ bpm).

q-bio.QM↗

arXiv2016

Noise-Compensated, Bias-Corrected Diffusion Weighted Endorectal Magnetic Resonance Imaging via a Stochastically Fully-Connected Joint Conditional Random Field Model

Diffusion weighted magnetic resonance imaging (DW-MR) is a powerful tool in imaging-based prostate cancer screening and detection. Endorectal coils are commonly used in DW-MR imaging to improve the signal-to-noise ratio (SNR) of the acquisition, at the expense of significant intensity inhomogeneities (bias field) that worsens as we move away from the endorectal coil. The presence of bias field can have a significant negative impact on the accuracy of different image analysis tasks, as well as prostate tumor localization, thus leading to increased inter- and intra-observer variability. Retrospective bias correction approaches are introduced as a more efficient way of bias correction compared to the prospective methods such that they correct for both of the scanner and anatomy-related bias fields in MR imaging. Previously proposed retrospective bias field correction methods suffer from undesired noise amplification that can reduce the quality of bias-corrected DW-MR image. Here, we propose a unified data reconstruction approach that enables joint compensation of bias field as well as data noise in DW-MR imaging. The proposed noise-compensated, bias-corrected (NCBC) data reconstruction method takes advantage of a novel stochastically fully connected joint conditional random field (SFC-JCRF) model to mitigate the effects of data noise and bias field in the reconstructed MR data. The proposed NCBC reconstruction method was tested on synthetic DW-MR data, physical DW-phantom as well as real DW-MR data all acquired using endorectal MR coil. Both qualitative and quantitative analysis illustrated that the proposed NCBC method can achieve improved image quality when compared to other tested bias correction methods. As such, the proposed NCBC method may have potential as a useful retrospective approach for improving the consistency of image interpretations.

stat.ME↗

arXiv2016

A spectral-spatial fusion model for robust blood pulse waveform extraction in photoplethysmographic imaging

Photoplethysmographic imaging is a camera-based solution for non-contact cardiovascular monitoring from a distance. This technology enables monitoring in situations where contact-based devices may be problematic or infeasible, such as ambulatory, sleep, and multi-individual monitoring. However, extracting the blood pulse waveform signal is challenging due to the unknown mixture of relevant (pulsatile) and irrelevant pixels in the scene. Here, we design and implement a signal fusion framework, FusionPPG, for extracting a blood pulse waveform signal with strong temporal fidelity from a scene without requiring anatomical priors (e.g., facial tracking). The extraction problem is posed as a Bayesian least squares fusion problem, and solved using a novel probabilistic pulsatility model that incorporates both physiologically derived spectral and spatial waveform priors to identify pulsatility characteristics in the scene. Experimental results show statistically significantly improvements compared to the FaceMeanPPG method ($p<0.001$) and DistancePPG ($p<0.001$) methods. Heart rates predicted using FusionPPG correlated strongly with ground truth measurements ($r^2=0.9952$). FusionPPG was the only method able to assess cardiac arrhythmia via temporal analysis.

cs.CV↗

arXiv2016

Laser light-field fusion for wide-field lensfree on-chip phase contrast nanoscopy

Wide-field lensfree on-chip microscopy, which leverages holography principles to capture interferometric light-field encodings without lenses, is an emerging imaging modality with widespread interest given the large field-of-view compared to lens-based techniques. In this study, we introduce the idea of laser light-field fusion for lensfree on-chip phase contrast nanoscopy, where interferometric laser light-field encodings acquired using an on-chip setup with laser pulsations at different wavelengths are fused to produce marker-free phase contrast images of superior quality with resolving power more than five times below the pixel pitch of the sensor array and more than 40% beyond the diffraction limit. As a proof of concept, we demonstrate, for the first time, a wide-field lensfree on-chip instrument successfully detecting 300 nm particles, resulting in a numerical aperture of 1.1, across a large field-of-view of $\sim$ 30 mm$^2$ without any specialized or intricate sample preparation, or the use of synthetic aperture- or shift-based techniques.

physics.optics↗

arXiv2016

Non-contact hemodynamic imaging reveals the jugular venous pulse waveform

Cardiovascular monitoring is important to prevent diseases from progressing. The jugular venous pulse (JVP) waveform offers important clinical information about cardiac health, but is not routinely examined due to its invasive catheterisation procedure. Here, we demonstrate for the first time that the JVP can be consistently observed in a non-contact manner using a novel light-based photoplethysmographic imaging system, coded hemodynamic imaging (CHI). While traditional monitoring methods measure the JVP at a single location, CHI's wide-field imaging capabilities were able to observe the jugular venous pulse's spatial flow profile for the first time. The important inflection points in the JVP were observed, meaning that cardiac abnormalities can be assessed through JVP distortions. CHI provides a new way to assess cardiac health through non-contact light-based JVP monitoring, and can be used in non-surgical environments for cardiac assessment.

physics.med-ph↗

arXiv2016

Scene Invariant Crowd Segmentation and Counting Using Scale-Normalized Histogram of Moving Gradients (HoMG)

The problem of automated crowd segmentation and counting has garnered significant interest in the field of video surveillance. This paper proposes a novel scene invariant crowd segmentation and counting algorithm designed with high accuracy yet low computational complexity in mind, which is key for widespread industrial adoption. A novel low-complexity, scale-normalized feature called Histogram of Moving Gradients (HoMG) is introduced for highly effective spatiotemporal representation of individuals and crowds within a video. Real-time crowd segmentation is achieved via boosted cascade of weak classifiers based on sliding-window HoMG features, while linear SVM regression of crowd-region HoMG features is employed for real-time crowd counting. Experimental results using multi-camera crowd datasets show that the proposed algorithm significantly outperform state-of-the-art crowd counting algorithms, as well as achieve very promising crowd segmentation results, thus demonstrating the efficacy of the proposed method for highly-accurate, real-time video-driven crowd analysis.

cs.CV↗

arXiv2015

Sparse Reconstruction of Compressive Sensing MRI using Cross-Domain Stochastically Fully Connected Conditional Random Fields

Magnetic Resonance Imaging (MRI) is a crucial medical imaging technology for the screening and diagnosis of frequently occurring cancers. However image quality may suffer by long acquisition times for MRIs due to patient motion, as well as result in great patient discomfort. Reducing MRI acquisition time can reduce patient discomfort and as a result reduces motion artifacts from the acquisition process. Compressive sensing strategies, when applied to MRI, have been demonstrated to be effective at decreasing acquisition times significantly by sparsely sampling the \emph{k}-space during the acquisition process. However, such a strategy requires advanced reconstruction algorithms to produce high quality and reliable images from compressive sensing MRI. This paper proposes a new reconstruction approach based on cross-domain stochastically fully connected conditional random fields (CD-SFCRF) for compressive sensing MRI. The CD-SFCRF introduces constraints in both \emph{k}-space and spatial domains within a stochastically fully connected graphical model to produce improved MRI reconstruction. Experimental results using T2-weighted (T2w) imaging and diffusion-weighted imaging (DWI) of the prostate show strong performance in preserving fine details and tissue structures in the reconstructed images when compared to other tested methods even at low sampling rates.

cs.CV↗

arXiv2015

Domain Adaptation and Transfer Learning in StochasticNets

Transfer learning is a recent field of machine learning research that aims to resolve the challenge of dealing with insufficient training data in the domain of interest. This is a particular issue with traditional deep neural networks where a large amount of training data is needed. Recently, StochasticNets was proposed to take advantage of sparse connectivity in order to decrease the number of parameters that needs to be learned, which in turn may relax training data size requirements. In this paper, we study the efficacy of transfer learning on StochasticNet frameworks. Experimental results show ~7% improvement on StochasticNet performance when the transfer learning is applied in training step.

cs.CV↗

arXiv2015

Numerical Demultiplexing of Color Image Sensor Measurements via Non-linear Random Forest Modeling

The simultaneous capture of imaging data at multiple wavelengths across the electromagnetic spectrum is highly challenging, requiring complex and costly multispectral image sensors. In this study, we introduce a comprehensive framework for performing simultaneous multispectral imaging using conventional image sensors with color filter arrays via numerical demultiplexing of the color image sensor measurements. A numerical forward model characterizing the formation of sensor measurements from light spectra hitting the sensor is constructed based on a comprehensive spectral characterization of the sensor. A numerical demultiplexer is then learned via non-linear random forest modeling based on the forward model. Given the learned numerical demultiplexer, one can then demultiplex simultaneously-acquired measurements made by the image sensor into reflectance intensities at discrete selectable wavelengths, resulting in a higher resolution reflectance spectrum. Simulation and real-world experimental results demonstrate the efficacy of such a method for simultaneous multispectral imaging.

cs.CV↗

arXiv2015

Efficient Deep Feature Learning and Extraction via StochasticNets

Deep neural networks are a powerful tool for feature learning and extraction given their ability to model high-level abstractions in highly complex data. One area worth exploring in feature learning and extraction using deep neural networks is efficient neural connectivity formation for faster feature learning and extraction. Motivated by findings of stochastic synaptic connectivity formation in the brain as well as the brain's uncanny ability to efficiently represent information, we propose the efficient learning and extraction of features via StochasticNets, where sparsely-connected deep neural networks can be formed via stochastic connectivity between neurons. To evaluate the feasibility of such a deep neural network architecture for feature learning and extraction, we train deep convolutional StochasticNets to learn abstract features using the CIFAR-10 dataset, and extract the learned features from images to perform classification on the SVHN and STL-10 datasets. Experimental results show that features learned using deep convolutional StochasticNets, with fewer neural connections than conventional deep convolutional neural networks, can allow for better or comparable classification accuracy than conventional deep neural networks: relative test error decrease of ~4.5% for classification on the STL-10 dataset and ~1% for classification on the SVHN dataset. Furthermore, it was shown that the deep features extracted using deep convolutional StochasticNets can provide comparable classification accuracy even when only 10% of the training data is used for feature learning. Finally, it was also shown that significant gains in feature extraction speed can be achieved in embedded applications using StochasticNets. As such, StochasticNets allow for faster feature learning and extraction performance while facilitate for better or comparable accuracy performances.

cs.LG↗

arXiv2015

Discovery Radiomics via StochasticNet Sequencers for Cancer Detection

Radiomics has proven to be a powerful prognostic tool for cancer detection, and has previously been applied in lung, breast, prostate, and head-and-neck cancer studies with great success. However, these radiomics-driven methods rely on pre-defined, hand-crafted radiomic feature sets that can limit their ability to characterize unique cancer traits. In this study, we introduce a novel discovery radiomics framework where we directly discover custom radiomic features from the wealth of available medical imaging data. In particular, we leverage novel StochasticNet radiomic sequencers for extracting custom radiomic features tailored for characterizing unique cancer tissue phenotype. Using StochasticNet radiomic sequencers discovered using a wealth of lung CT data, we perform binary classification on 42,340 lung lesions obtained from the CT scans of 93 patients in the LIDC-IDRI dataset. Preliminary results show significant improvement over previous state-of-the-art methods, indicating the potential of the proposed discovery radiomics framework for improving cancer screening and diagnosis.

cs.CV↗

arXiv2015

StochasticNet: Forming Deep Neural Networks via Stochastic Connectivity

Deep neural networks is a branch in machine learning that has seen a meteoric rise in popularity due to its powerful abilities to represent and model high-level abstractions in highly complex data. One area in deep neural networks that is ripe for exploration is neural connectivity formation. A pivotal study on the brain tissue of rats found that synaptic formation for specific functional connectivity in neocortical neural microcircuits can be surprisingly well modeled and predicted as a random formation. Motivated by this intriguing finding, we introduce the concept of StochasticNet, where deep neural networks are formed via stochastic connectivity between neurons. As a result, any type of deep neural networks can be formed as a StochasticNet by allowing the neuron connectivity to be stochastic. Stochastic synaptic formations, in a deep neural network architecture, can allow for efficient utilization of neurons for performing specific tasks. To evaluate the feasibility of such a deep neural network architecture, we train a StochasticNet using four different image datasets (CIFAR-10, MNIST, SVHN, and STL-10). Experimental results show that a StochasticNet, using less than half the number of neural connections as a conventional deep neural network, achieves comparable accuracy and reduces overfitting on the CIFAR-10, MNIST and SVHN dataset. Interestingly, StochasticNet with less than half the number of neural connections, achieved a higher accuracy (relative improvement in test error rate of ~6% compared to ConvNet) on the STL-10 dataset than a conventional deep neural network. Finally, StochasticNets have faster operational speeds while achieving better or similar accuracy performances.

cs.CV↗

arXiv2015

Discovery Radiomics for Multi-Parametric MRI Prostate Cancer Detection

Prostate cancer is the most diagnosed form of cancer in Canadian men, and is the third leading cause of cancer death. Despite these statistics, prognosis is relatively good with a sufficiently early diagnosis, making fast and reliable prostate cancer detection crucial. As imaging-based prostate cancer screening, such as magnetic resonance imaging (MRI), requires an experienced medical professional to extensively review the data and perform a diagnosis, radiomics-driven methods help streamline the process and has the potential to significantly improve diagnostic accuracy and efficiency, and thus improving patient survival rates. These radiomics-driven methods currently rely on hand-crafted sets of quantitative imaging-based features, which are selected manually and can limit their ability to fully characterize unique prostate cancer tumour phenotype. In this study, we propose a novel \textit{discovery radiomics} framework for generating custom radiomic sequences tailored for prostate cancer detection. Discovery radiomics aims to uncover abstract imaging-based features that capture highly unique tumour traits and characteristics beyond what can be captured using predefined feature models. In this paper, we discover new custom radiomic sequencers for generating new prostate radiomic sequences using multi-parametric MRI data. We evaluated the performance of the discovered radiomic sequencer against a state-of-the-art hand-crafted radiomic sequencer for computer-aided prostate cancer detection with a feedforward neural network using real clinical prostate multi-parametric MRI data. Results for the discovered radiomic sequencer demonstrate good performance in prostate cancer detection and clinical decision support relative to the hand-crafted radiomic sequencer. The use of discovery radiomics shows potential for more efficient and reliable automatic prostate cancer detection.

cs.CV↗

arXiv2015

A Deep-structured Conditional Random Field Model for Object Silhouette Tracking

In this work, we introduce a deep-structured conditional random field (DS-CRF) model for the purpose of state-based object silhouette tracking. The proposed DS-CRF model consists of a series of state layers, where each state layer spatially characterizes the object silhouette at a particular point in time. The interactions between adjacent state layers are established by inter-layer connectivity dynamically determined based on inter-frame optical flow. By incorporate both spatial and temporal context in a dynamic fashion within such a deep-structured probabilistic graphical model, the proposed DS-CRF model allows us to develop a framework that can accurately and efficiently track object silhouettes that can change greatly over time, as well as under different situations such as occlusion and multiple targets within the scene. Experiment results using video surveillance datasets containing different scenarios such as occlusion and multiple targets showed that the proposed DS-CRF approach provides strong object silhouette tracking performance when compared to baseline methods such as mean-shift tracking, as well as state-of-the-art methods such as context tracking and boosted particle filtering.

cs.CV↗

arXiv2015

A Weakly Supervised Learning Approach based on Spectral Graph-Theoretic Grouping

In this study, a spectral graph-theoretic grouping strategy for weakly supervised classification is introduced, where a limited number of labelled samples and a larger set of unlabelled samples are used to construct a larger annotated training set composed of strongly labelled and weakly labelled samples. The inherent relationship between the set of strongly labelled samples and the set of unlabelled samples is established via spectral grouping, with the unlabelled samples subsequently weakly annotated based on the strongly labelled samples within the associated spectral groups. A number of similarity graph models for spectral grouping, including two new similarity graph models introduced in this study, are explored to investigate their performance in the context of weakly supervised classification in handling different types of data. Experimental results using benchmark datasets as well as real EMG datasets demonstrate that the proposed approach to weakly supervised classification can provide noticeable improvements in classification performance, and that the proposed similarity graph models can lead to ultimate learning results that are either better than or on a par with existing similarity graph models in the context of spectral grouping for weakly supervised classification.

cs.LG↗

arXiv2015

Lensfree Spectral Light-field Fusion Microscopy for Contrast- and Resolution-enhanced Imaging of Biological Specimens

A lensfree spectral light-field fusion microscopy (LSLFM) system is presented for enabling contrast- and resolution-enhanced imaging of biological specimens. LSLFM consists of a pulsed multispectral lensfree microscope for capturing interferometric light-field encodings at various wavelengths, and Bayesian-based fusion to reconstruct a fused object light-field from the encodings. By fusing unique object detail information captured at different wavelengths, LSLFM can achieve improved resolution, contrast, and signal-to-noise ratio (SNR) over a single-channel lensfree microscopy system. A five-channel LSLFM system was developed and quantitatively evaluated to validate the design. Experimental results demonstrated that the LSLFM system provided SNR improvements of 6-12 dB, as well as a six-fold improvement in the dispersion index (DI), over that achieved using a single-channel, resolution-enhancing lensfree deconvolution microscopy system or its multi-wavelength counterpart. Furthermore, the LSLFM system achieved an increase in numerical aperture (NA) of ~16% over a single-channel resolution-enhancing lensfree deconvolution microscopy system at the highest-resolution wavelength used in the study. Samples of Staurastrum paradoxum, a waterborne algae, and human corneal epithelial cells were imaged using the system to illustrate its potential for enhanced imaging of biological specimens.

physics.optics↗