arXiv subjects

Aman Singh

Publications and source records attributed to Aman Singh.

21 records · Page 2Linked to original sources

arXiv2020

Machine-Learning Driven Drug Repurposing for COVID-19

The integration of machine learning methods into bioinformatics provides particular benefits in identifying how therapeutics effective in one context might have utility in an unknown clinical context or against a novel pathology. We aim to discover the underlying associations between viral proteins and antiviral therapeutics that are effective against them by employing neural network models. Using the National Center for Biotechnology Information virus protein database and the DrugVirus database, which provides a comprehensive report of broad-spectrum antiviral agents (BSAAs) and viruses they inhibit, we trained ANN models with virus protein sequences as inputs and antiviral agents deemed safe-in-humans as outputs. Model training excluded SARS-CoV-2 proteins and included only Phases II, III, IV and Approved level drugs. Using sequences for SARS-CoV-2 (the coronavirus that causes COVID-19) as inputs to the trained models produces outputs of tentative safe-in-human antiviral candidates for treating COVID-19. Our results suggest multiple drug candidates, some of which complement recent findings from noteworthy clinical studies. Our in-silico approach to drug repurposing has promise in identifying new drug candidates and treatments for other viruses.

cs.LG↗

arXiv2020

Usage Analysis of Mobile Devices

Mobile devices have evolved from just communication devices into an indispensable part of people's lives in form of smartphones, tablets and smart watches. Devices are now more personal than ever and carry more information about a person than any other. Extracting user behaviour is rather difficult and time-consuming as most of the work previously has been manual or requires feature extraction. In this paper, a novel approach of user behavior detection is proposed with Deep Learning Network (DNN). Initial approach was to use recurrent neural network (RNN) along with LSTM for completely unsupervised analysis of mobile devices. Next approach is to extract features by using Long Short Term Memory (LSTM) to understand the user behaviour, which are then fed into the Convolution Neural Network (CNN). This work mainly concentrates on detection of user behaviour and anomaly detection for usage analysis of mobile devices. Both the approaches are compared against some baseline methods. Experiments are conducted on the publicly available dataset to show that these methods can successfully capture the user behaviors.

cs.CY↗

arXiv2019

SynGAN: Towards Generating Synthetic Network Attacks using GANs

The rapid digital transformation without security considerations has resulted in the rise of global-scale cyberattacks. The first line of defense against these attacks are Network Intrusion Detection Systems (NIDS). Once deployed, however, these systems work as blackboxes with a high rate of false positives with no measurable effectiveness. There is a need to continuously test and improve these systems by emulating real-world network attack mutations. We present SynGAN, a framework that generates adversarial network attacks using the Generative Adversial Networks (GAN). SynGAN generates malicious packet flow mutations using real attack traffic, which can improve NIDS attack detection rates. As a first step, we compare two public datasets, NSL-KDD and CICIDS2017, for generating synthetic Distributed Denial of Service (DDoS) network attacks. We evaluate the attack quality (real vs. synthetic) using a gradient boosting classifier.

cs.LG↗