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Amir Rahmani

Publications and source records attributed to Amir Rahmani.

At least 19 recordsLinked to original sources

PSyGenTAB: A Privacy-Preserving Framework for Synthetic Clinical Tabular Data Generation via Constrained Optimization

The development of medical AI is constrained by limited access to high-quality clinical data due to institutional silos and strict privacy regulations such as HIPAA and GDPR. Synthetic data generation offers a potential solution, but existing methods lack principled mechanisms to explicitly manage the privacy-utility trade-off, often degrading clinically meaningful patterns or risking patient re-identification. We present PSyGenTAB, a privacy-preserving generative framework that formulates synthetic healthcare data generation as a constrained optimization problem solved using the Augmented Lagrangian Method. By embedding configurable privacy constraints directly into model training, PSyGenTAB enforces minimum privacy thresholds while maximizing clinical data utility. Across multiple clinically motivated benchmarks, PSyGenTAB preserves inter-feature clinical relationships and minority-class diagnostic patterns essential for reliable health AI. Downstream evaluation using Train-on-Synthetic, Test-on-Real and Train-on-Real, Test-on-Synthetic protocols shows that models trained on synthetic data achieve performance comparable to those trained on real patient records. Privacy auditing further demonstrates reduced exact record reproduction and strong resilience to membership inference attacks. These results establish PSyGenTAB as a principled framework for balancing privacy protection and clinical utility in synthetic healthcare data, supporting secure cross-institutional AI development.

cs.LG

Personal Care Utility: Health as Everyday Infrastructure

Healthcare is essential, expert, and episodic by design - built around the roughly one hour per year a person spends with a clinician. The 8,759 hours outside clinical settings, where eating, sleeping, movement, medication, and stress actually shape long-term health, have no comparable infrastructure. The bottleneck for personalized health is not raw data or reasoning capability; it is the absence of that infrastructure layer. This paper introduces the Personal Care Utility (PCU): a layered, event-driven architecture proposed as the missing utility for everyday health, in the way that payments, networks, and power are utilities for their domains. PCU organizes continuous personal signals into semantically meaningful life events through a Personicle, estimates dynamic health state against personal baselines, reasons about cause and context, and routes guidance through an orchestrator that separates clinical decision logic, behavioral strategy selection, and natural-language expression. This separation lets large language models support reasoning and communication while keeping safety-critical clinical decisions grounded in validated evidence. We instantiate PCU for Type 2 Diabetes - turning CGM, meal, activity, medication, sleep, stress, and clinical data into glycemic events, individualized state estimates, causal explanations, and knowledge-grounded interventions. A day-in-the-life scenario shows the same infrastructure producing real-time nudges, weekly summaries, medication check-ins, silence, or deterministic safety alerts depending on context and risk. We close with how PCU generalizes to other chronic conditions and the governance questions any always-on personal health utility must address. The result is a blueprint that treats personalization not as a final messaging layer, but as an architectural property of everyday health guidance.

cs.CL

CARE-ECG: Causal Agent-based Reasoning for Explainable and Counterfactual ECG Interpretation

Large language models (LLMs) enable waveform-to-text ECG interpretation and interactive clinical questioning, yet most ECG-LLM systems still rely on weak signal-text alignment and retrieval without explicit physiological or causal structure. This limits grounding, temporal reasoning, and counterfactual "what-if" analysis central to clinical decision-making. We propose CARE-ECG, a causally structured ECG-language reasoning framework that unifies representation learning, diagnosis, and explanation in a single pipeline. CARE-ECG encodes multi-lead ECGs into temporally organized latent biomarkers, performs causal graph inference for probabilistic diagnosis, and supports counterfactual assessment via structural causal models. To improve faithfulness, CARE-ECG grounds language outputs through causal retrieval-augmented generation and a modular agentic pipeline that integrates history, diagnosis, and response with verification. Across multiple ECG benchmarks and expert QA settings, CARE-ECG improves diagnostic accuracy and explanation faithfulness while reducing hallucinations (e.g., 0.84 accuracy on Expert-ECG-QA and 0.76 on SCP-mapped PTB-XL under GPT-4). Overall, CARE-ECG provides traceable reasoning by exposing key latent drivers, causal evidence paths, and how alternative physiological states would change outcomes.

cs.LG

Membership Inference Attacks Expose Participation Privacy in ECG Foundation Encoders

Foundation-style ECG encoders pretrained with self-supervised learning are increasingly reused across tasks, institutions, and deployment contexts, often through model-as-a-service interfaces that expose scalar scores or latent representations. While such reuse improves data efficiency and generalization, it raises a participation privacy concern: can an adversary infer whether a specific individual or cohort contributed ECG data to pretraining, even when raw waveforms and diagnostic labels are never disclosed? In connected-health settings, training participation itself may reveal institutional affiliation, study enrollment, or sensitive health context. We present an implementation-grounded audit of membership inference attacks (MIAs) against modern self-supervised ECG foundation encoders, covering contrastive objectives (SimCLR, TS2Vec) and masked reconstruction objectives (CNN- and Transformer-based MAE). We evaluate three realistic attacker interfaces: (i) score-only black-box access to scalar outputs, (ii) adaptive learned attackers that aggregate subject-level statistics across repeated queries, and (iii) embedding-access attackers that probe latent representation geometry. Using a subject-centric protocol with window-to-subject aggregation and calibration at fixed false-positive rates under a cross-dataset auditing setting, we observe heterogeneous and objective-dependent participation leakage: leakage is most pronounced in small or institution-specific cohorts and, for contrastive encoders, can saturate in embedding space, while larger and more diverse datasets substantially attenuate operational tail risk. Overall, our results show that restricting access to raw signals or labels is insufficient to guarantee participation privacy, underscoring the need for deployment-aware auditing of reusable biosignal foundation encoders in connected-health systems.

cs.LG

DISCO-TAB: A Hierarchical Reinforcement Learning Framework for Privacy-Preserving Synthesis of Complex Clinical Data

The development of robust clinical decision support systems is frequently impeded by the scarcity of high-fidelity, privacy-preserving biomedical data. While Generative Large Language Models (LLMs) offer a promising avenue for synthetic data generation, they often struggle to capture the complex, non-linear dependencies and severe class imbalances inherent in Electronic Health Records (EHR), leading to statistically plausible but clinically invalid records. To bridge this gap, we introduce DISCO-TAB (DIScriminator-guided COntrol for TABular synthesis), a novel framework that orchestrates a fine-tuned LLM with a multi-objective discriminator system optimized via Reinforcement Learning. Unlike prior methods relying on scalar feedback, DISCO-TAB evaluates synthesis at four granularities, token, sentence, feature, and row, while integrating Automated Constraint Discovery and Inverse-Frequency Reward Shaping to autonomously preserve latent medical logic and resolve minority-class collapse. We rigorously validate our framework across diverse benchmarks, including high-dimensional, small-sample medical datasets (e.g., Heart Failure, Parkinson's). Our results demonstrate that hierarchical feedback yields state-of-the-art performance, achieving up to 38.2% improvement in downstream clinical classifier utility compared to GAN and Diffusion baselines, while ensuring exceptional statistical fidelity (JSD < 0.01) and robust resistance to membership inference attacks. This work establishes a new standard for generating trustworthy, utility-preserving synthetic tabular data for sensitive healthcare applications.

cs.LG

Strongly Nonlinear Slow Light Polaritons in Subwavelength Modulated Waveguides

Slow light is a regime of reduced group velocity, resulting in increased photon density in optical pulses and enhanced nonlinear effects. Here, we propose the realization of slow light in the regime of strong light-matter interaction between waveguide photons and semiconductor excitons. We design a dielectric superlattice structure with a nearly-flat band characterized by low group velocity and group velocity dispersion, both required for enhancing nonlinear effects with ultrashort pulses. Furthermore, by applying this general framework to a perovskite-based structure, we demonstrate an enhancement of the single-particle phase shift by a factor of more than 20, representing a significant step toward the few-photon quantum regime. Our results provide a blueprint for accessible strong interactions in solid-state integrated optics.

physics.optics

MedSpeak: A Knowledge Graph-Aided ASR Error Correction Framework for Spoken Medical QA

Spoken question-answering (SQA) systems relying on automatic speech recognition (ASR) often struggle with accurately recognizing medical terminology. To this end, we propose MedSpeak, a novel knowledge graph-aided ASR error correction framework that refines noisy transcripts and improves downstream answer prediction by leveraging both semantic relationships and phonetic information encoded in a medical knowledge graph, together with the reasoning power of LLMs. Comprehensive experimental results on benchmarks demonstrate that MedSpeak significantly improves the accuracy of medical term recognition and overall medical SQA performance, establishing MedSpeak as a state-of-the-art solution for medical SQA. The code is available at https://github.com/RainieLLM/MedSpeak.

cs.CL

Quantum Light Detection with Enhanced Photonic Neural Network

Advances in quantum technologies are accelerating the demand for optical quantum state sensors that combine high precision, versatility, and scalability within a unified hardware platform. Quantum reservoir computing offers a powerful route toward this goal by exploiting the nonlinear dynamics of quantum systems to process and interpret quantum information efficiently. Photonic neural networks are particularly well suited for such implementations, owing to their intrinsic sensitivity to photon-encoded quantum information. However, the practical realisation of photonic quantum reservoirs remains constrained by the inherently weak optical nonlinearities of available materials and the technological challenges of fabricating densely coupled quantum networks. To address these limitations, we introduce a hybrid quantum-classical detection protocol that integrates the advantages of quantum reservoirs with the adaptive learning capabilities of analogue neural networks. This synergistic architecture substantially enhances information-extraction accuracy and robustness, enabling low-cost performance improvements of quantum light sensors. Based on the proposed approach, we achieved significant improvements in quantum state classification, tomography, and feature regression, even for reservoirs with a relatively small nonlinearity-to-losses ratio $U/\gamma \approx 0.02$ in a network of only five nodes. By reducing reliance on material nonlinearity and reservoir size, the proposed approach facilitates the practical deployment of high-fidelity photonic quantum sensors on existing integrated platforms, paving the way toward chip-scale quantum processors and photonic sensing technologies.

quant-ph

DemMA: Dementia Multi-Turn Dialogue Agent with Expert-Guided Reasoning and Action Simulation

Simulating dementia patients with large language models (LLMs) is challenging due to the need to jointly model cognitive impairment, emotional dynamics, and nonverbal behaviors over long conversations. We present DemMA, an expert-guided dementia dialogue agent for high-fidelity multi-turn patient simulation. DemMA constructs clinically grounded dementia personas by integrating pathology information, personality traits, and subtype-specific memory-status personas informed by clinical experts. To move beyond text-only simulation, DemMA explicitly models nonverbal behaviors, including motion, facial expressions, and vocal cues. We further introduce a Chain-of-Thought distillation framework that trains a single LLM to jointly generate reasoning traces, patient utterances, and aligned behavioral actions within one forward pass, enabling efficient deployment without multi-agent inference. Extensive evaluations with experts, medical students, and LLM judges demonstrate that DemMA significantly outperforms strong baselines across multiple metrics.

cs.MA

Information-Driven Fault Detection and Identification for Multi-Agent Spacecraft Systems: Collaborative On-Orbit Inspection Mission

This work presents a global-to-local, task-aware fault detection and identification (FDI) framework for multi-spacecraft systems conducting collaborative inspection missions in low Earth orbit. The inspection task is represented by a global information-driven cost functional that integrates the sensor model, spacecraft poses, and mission-level information-gain objectives. This formulation links guidance, control, and FDI by using the same cost function to drive both global task allocation and local sensing or motion decisions. Fault detection is achieved through comparisons between expected and observed task metrics, while higher-order cost-gradient measures enable the identification of faults among sensors, actuators, and state estimators. An adaptive thresholding mechanism captures the time-varying inspection geometry and dynamic mission conditions. Simulation results for representative multi-spacecraft inspection scenarios demonstrate the reliability of fault localization and classification under uncertainty, providing a unified, information-driven foundation for resilient autonomous inspection architectures.

eess.SY

MIMIC-Sepsis: A Curated Benchmark for Modeling and Learning from Sepsis Trajectories in the ICU

Sepsis is a leading cause of mortality in intensive care units (ICUs), yet existing research often relies on outdated datasets, non-reproducible preprocessing pipelines, and limited coverage of clinical interventions. We introduce MIMIC-Sepsis, a curated cohort and benchmark framework derived from the MIMIC-IV database, designed to support reproducible modeling of sepsis trajectories. Our cohort includes 35,239 ICU patients with time-aligned clinical variables and standardized treatment data, including vasopressors, fluids, mechanical ventilation and antibiotics. We describe a transparent preprocessing pipeline-based on Sepsis-3 criteria, structured imputation strategies, and treatment inclusion-and release it alongside benchmark tasks focused on early mortality prediction, length-of-stay estimation, and shock onset classification. Empirical results demonstrate that incorporating treatment variables substantially improves model performance, particularly for Transformer-based architectures. MIMIC-Sepsis serves as a robust platform for evaluating predictive and sequential models in critical care research.

cs.LG

Safe Payload Transfer with Ship-Mounted Cranes: A Robust Model Predictive Control Approach

Ensuring safe real-time control of ship-mounted cranes in unstructured transportation environments requires handling multiple safety constraints while maintaining effective payload transfer performance. Unlike traditional crane systems, ship-mounted cranes are consistently subjected to significant external disturbances affecting underactuated crane dynamics due to the ship's dynamic motion response to harsh sea conditions, which can lead to robustness issues. To tackle these challenges, we propose a robust and safe model predictive control (MPC) framework and demonstrate it on a 5-DOF crane system, where a Stewart platform simulates the external disturbances that ocean surface motions would have on the supporting ship. The crane payload transfer operation must avoid obstacles and accurately place the payload within a designated target area. We use a robust zero-order control barrier function (R-ZOCBF)-based safety constraint in the nonlinear MPC to ensure safe payload positioning, while time-varying bounding boxes are utilized for collision avoidance. We introduce a new optimization-based online robustness parameter adaptation scheme to reduce the conservativeness of R-ZOCBFs. Experimental trials on a crane prototype demonstrate the overall performance of our safe control approach under significant perturbing motions of the crane base. While our focus is on crane-facilitated transfer, the methods more generally apply to safe robotically-assisted parts mating and parts insertion.

eess.SY

Quantization of Polaritons Confined in Dielectric Structures

Light-matter interaction in the regime of strong quantum coupling is usually treated within the framework of the Hopfield model. However, the picture of coupling well-defined modes of light and matter is correct only as long as the shapes of these eigenmodes are not substantially modified by the interaction. Moreover, parameters of theoretical models are usually obtained by fitting to experimental data. To date, there is no straightforward method to determine a quantum master equation corresponding to a system with specific dielectric structure, which may lead to incompatibility of theoretical descriptions and physical realizations. In this work, a recipe for obtaining a quantum model in the polariton eigenmode basis is presented, based on Bogoliubov transformation in the conservative case and third quantization technique in the dissipative case. It is shown how this method can be used for boosting interaction strength and engineering nonlocal many-body interactions in carefully designed nanostructures, resulting in strongly nonclassical correlations of emitted light.

quant-ph

Global Task-aware Fault Detection, Identification For On-Orbit Multi-Spacecraft Collaborative Inspection

In this paper, we present a global-to-local task-aware fault detection and identification algorithm to detect failures in a multi-spacecraft system performing a collaborative inspection (referred to as global) task. The inspection task is encoded as a cost functional $\costH$ that informs global (task allocation and assignment) and local (agent-level) decision-making. The metric $\costH$ is a function of the inspection sensor model, and the agent full-pose. We use the cost functional $\costH$ to design a metric that compares the expected and actual performance to detect the faulty agent using a threshold. We use higher-order cost gradients $\costH$ to derive a new metric to identify the type of fault, including task-specific sensor fault, an agent-level actuator, and sensor faults. Furthermore, we propose an approach to design adaptive thresholds for each fault mentioned above to incorporate the time dependence of the inspection task. We demonstrate the efficacy of the proposed method empirically, by simulating and detecting faults (such as inspection sensor faults, actuators, and sensor faults) in a low-Earth orbit collaborative spacecraft inspection task using the metrics and the threshold designed using the global task cost $\costH$.

eess.SY

Estimation of the second-order coherence function using quantum reservoir and ensemble methods

We propose a machine learning-based approach enhanced by quantum reservoir computing (QRC) to estimate the zero-time second-order correlation function g2(0). Typically, measuring g2(0) requires single-photon detectors and time-correlated measurements. Machine learning may offer practical solutions by training a model to estimate g2(0) solely from average intensity measurements. In our method, emission from a given quantum source is first processed in QRC. During the inference phase, only intensity measurements are used, which are then passed to a software-based decision tree-based ensemble model. We evaluate this hybrid quantum-classical approach across a variety of quantum optical systems and demonstrate that it provides accurate estimates of g2(0). We further extend our analysis to assess the ability of a trained model to generalize beyond its training distribution, both to the same system under different physical parameters and to fundamentally different quantum sources. While the model may yield reliable estimates within specific regimes, its performance across distinct systems is generally limited.

quant-ph

DEMENTIA-PLAN: An Agent-Based Framework for Multi-Knowledge Graph Retrieval-Augmented Generation in Dementia Care

Mild-stage dementia patients primarily experience two critical symptoms: severe memory loss and emotional instability. To address these challenges, we propose DEMENTIA-PLAN, an innovative retrieval-augmented generation framework that leverages large language models to enhance conversational support. Our model employs a multiple knowledge graph architecture, integrating various dimensional knowledge representations including daily routine graphs and life memory graphs. Through this multi-graph architecture, DEMENTIA-PLAN comprehensively addresses both immediate care needs and facilitates deeper emotional resonance through personal memories, helping stabilize patient mood while providing reliable memory support. Our notable innovation is the self-reflection planning agent, which systematically coordinates knowledge retrieval and semantic integration across multiple knowledge graphs, while scoring retrieved content from daily routine and life memory graphs to dynamically adjust their retrieval weights for optimized response generation. DEMENTIA-PLAN represents a significant advancement in the clinical application of large language models for dementia care, bridging the gap between AI tools and caregivers interventions.

cs.AI

Personalized Causal Graph Reasoning for LLMs: An Implementation for Dietary Recommendations

Large Language Models (LLMs) excel at general-purpose reasoning by leveraging broad commonsense knowledge, but they remain limited in tasks requiring personalized reasoning over multifactorial personal data. This limitation constrains their applicability in domains such as healthcare, where decisions must adapt to individual contexts. We introduce Personalized Causal Graph Reasoning, a framework that enables LLMs to reason over individual-specific causal graphs constructed from longitudinal data. Each graph encodes how user-specific factors influence targeted outcomes. In response to a query, the LLM traverses the graph to identify relevant causal pathways, rank them by estimated impact, simulate potential outcomes, and generate tailored responses. We implement this framework in the context of nutrient-oriented dietary recommendations, where variability in metabolic responses demands personalized reasoning. Using counterfactual evaluation, we assess the effectiveness of LLM-generated food suggestions for glucose control. Our method reduces postprandial glucose iAUC across three time windows compared to prior approaches. Additional LLM-as-a-judge evaluations further confirm improvements in personalization quality.

cs.CL

Room temperature exciton-polariton neural network with perovskite crystal

Limitations of electronics have stimulated the search for novel unconventional computing platforms that enable energy-efficient and ultra-fast information processing. Among various systems, exciton-polaritons stand out as promising candidates for the realization of optical neuromorphic devices. This is due to their unique hybrid light-matter properties, resulting in strong optical nonlinearity and excellent transport capabilities. However, previous implementations of polariton neural networks have been restricted to cryogenic temperatures, limiting their practical applications. In this work, using non-equillibrium Bose-Einstein condensation in a monocrystalline perovskite waveguide, we demonstrate the first room-temperature exciton-polariton neural network. Its performance is verified in various machine learning tasks, including binary classification, and object detection. Our result is a crucial milestone in the development of practical applications of polariton neural networks and provides new perspectives for optical computing accelerators based on perovskites.

physics.optics