arXiv subjects

Amirhossein Saba

Publications and source records attributed to Amirhossein Saba.

5 recordsLinked to original sources

arXiv2024

Second-harmonic optical diffraction tomography

Optical diffraction tomography (ODT) has emerged as an important label-free tool in biomedicine to measure the three-dimensional (3D) structure of a biological sample. In this paper, we describe ODT using second-harmonic generation (SHG) which is a coherent nonlinear optical process with a strict symmetry selectivity and has several advantages over traditional fluorescence methods. We report the tomographic retrieval of the 3D second-order nonlinear optical susceptibility using two-dimensional holographic measurements of the SHG fields at different illumination angles and polarization states. The method is a generalization of the conventional linear ODT to the nonlinear scenario. We demonstrate the method with a numerically simulated nanoparticle distribution and an experiment with muscle tissue fibers. Our results show that SHG ODT does not only provide an effective contrast mechanism for label-free imaging but also due to the symmetry requirement enables the visualization of properties that are not otherwise accessible.

physics.optics↗

arXiv2022

Predicting nonlinear optical scattering with physics-driven neural networks

Deep neural networks trained on physical losses are emerging as promising surrogates of nonlinear numerical solvers. These tools can predict solutions of Maxwell's equations and compute gradients of output fields with respect to the material and geometrical properties in millisecond times which makes them attractive for inverse design or inverse scattering applications. Here we develop a tunable version of MaxwellNet, a physics driven neural network able to compute light scattering from inhomogenous media with a size comparable with the incident wavelength in the presence of the optical Kerr effect. The weights of the network are dynamically adjusted to take into account the intensity-dependent refractive index of the material.

physics.optics↗

arXiv2022

Physics-informed neural networks for diffraction tomography

We propose a physics-informed neural network as the forward model for tomographic reconstructions of biological samples. We demonstrate that by training this network with the Helmholtz equation as a physical loss, we can predict the scattered field accurately. It will be shown that a pretrained network can be fine-tuned for different samples and used for solving the scattering problem much faster than other numerical solutions. We evaluate our methodology with numerical and experimental results. Our physics-informed neural networks can be generalized for any forward and inverse scattering problem.

physics.optics↗

arXiv2022

Optical Diffraction Tomography based on 3D Physics-Inspired Neural Network (PINN)

Optical diffraction tomography (ODT) is an emerging 3D imaging technique that is used for the 3D reconstruction of the refractive index (RI) for semi-transparent samples. Various inverse models have been proposed to reconstruct the 3D RI based on the holographic detection of different samples such as the Born and the Rytov approximations. However, such approximations usually suffer from the so-called missing-cone problem that results in an elongation of the final reconstruction along the optical axis. Different iterative schemes have been proposed to solve the missing cone problem relying on physical forward models and an error function that aims at filling in the k-space and thus eliminating the missing-cone problem and reaching better reconstruction accuracy. In this paper, we propose a different approach where a 3D neural network (NN) is employed. The NN is trained with a cost function derived from a physical model based on the physics of optical wave propagation. The 3D NN starts with an initial guess for the 3D RI reconstruction (i.e. Born, or Rytov) and aims at reconstructing better 3D reconstruction based on an error function. With this technique, the NN can be trained without any examples of the relation between the ill-posed reconstruction (Born or Rytov) and the ground truth (true shape).

physics.optics↗

arXiv2017

Two Dimensional Edge Detection by Guided Mode Resonant Metasurface

In this letter, a new approach to perform edge detection is presented using an all-dielectric CMOS-compatible metasurface. The design is based on guided-mode resonance which provides a high quality factor resonance to make the edge detection experimentally realizable. The proposed structure that is easy to fabricate, can be exploited for detection of edges in two dimensions due to its symmetry. Also, the trade-off between gain and resolution of edge detection is discussed which can be adjusted by appropriate design parameters. The proposed edge detector has also the potential to be used in ultrafast analog computing and image processing.

physics.optics↗