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An Phan

Publications and source records attributed to An Phan.

3 recordsLinked to original sources

M-LINKX: Multiview Graph Learning for Brain Cognitive Disease Detection

Electroencephalogram (EEG) is a non-invasive and relatively low-cost procedure that measures brain electricity for the detection of cognitive diseases. EEG-based classification of dementia-related conditions, including Alzheimer's disease (AD), mild cognitive impairment (MCI), and frontotemporal dementia (FTD), remains challenging because EEG signals are noisy, non-stationary, and vary across subjects. Segment-based learning provides a practical way to model long EEG recordings by converting them into fixed-length inputs. For each segment, discriminative information may be explored by using signals within each channel (i.e. electrode), as well as interactions between EEG channels. In this paper, we propose M-LINKX, a multi-view graph learning framework for EEG-based dementia classification. For each segment, we extract channel-level node features and construct multiple functional-connectivity (FC) graph views, where each view is defined by a specific combination of connectivity metric, frequency band, and topology filter, respectively. Instead of relying on message passing over the constructed graphs, M-LINKX follows a simple design in modeling node features and adjacency-based connectivity representations. The graph-view representations are fused using global trainable view weights, and subject-level prediction is obtained by averaging segment-level probabilities. Experiments on two three-class EEG datasets with different diagnostic groups, CAUEEG (HC/MCI/Dementia) and AHEAP (HC/AD/FTD), show that M-LINKX achieves the best subject-level performance under the main experimental settings. Our study suggests that multi-view functional connectivity can improve EEG-based dementia classification when integrated with an appropriate graph-learning architecture. Code and data are available at https://github.com/anphantt/MLINKX.

cs.LG

LAFA: A Framework for Reproducible Longitudinal Assessment of Protein Function Annotation Models

Motivation: Protein function prediction is a challenging task and an open problem in computational biology. The Critical Assessment of protein Function Annotation (CAFA) is a triennial, community-driven initiative that provides an independent, large-scale evaluation of computational methods for protein function prediction through time-delayed benchmarking experiments. CAFA has played a key role in highlighting high-performing methodologies and fostering detailed analysis and exchange of ideas. However, outside the periodic CAFA challenges, there is no platform for the continuous evaluation of newly developed methods and tracking performance as function annotations accumulate. Results: Here we introduce the Longitudinal Assessment of Protein Function Annotation Models server (LAFA) as a persistent benchmarking system for protein function prediction methods. LAFA provides a continuous evaluation of containerized function prediction methods, enabling up-to-date and robust comparative assessment of method performance under evolving ground truth. LAFA accelerates methodological iteration, supports reproducibility, and offers a more dynamic and fine-grained view of progress in protein function prediction. Code and Data Availability: LAFA is available at https://functionbench.net/. Detailed evaluation results can be found at https://github.com/anphan0828/CAFA_forever

q-bio.QM

Llamarine: Open-source Maritime Industry-specific Large Language Model

Large Language Models (LLMs) have demonstrated substantial potential in addressing complex reasoning tasks, yet their general-purpose nature often limits their effectiveness in specialized domains such as maritime navigation. To bridge this gap, we introduce Llamarine, the first open-source LLM designed specifically for maritime navigation. Llamarine 1.0 is developed through continued pretraining and fine-tuning on a high-quality corpus comprising maritime textbooks, research publications, and web text from Wikipedia. This domain-specific training enables the model to acquire expert-level knowledge in navigational principles, collision avoidance, route optimization, and regulatory compliance. Our key contributions include (a) the curation of a comprehensive maritime dataset from authoritative sources, ensuring depth and reliability in the model's knowledge base; (b) the development of a foundational model capable of reasoning about complex navigational challenges with greater accuracy than general-purpose LLMs; and (c) the establishment of a benchmark to evaluate performance in maritime-specific decision-making tasks. Experimental results demonstrate that Llamarine outperforms both general-purpose and commercial LLMs in critical navigation-related tasks, such as trajectory planning, risk assessment, and compliance with maritime regulations. By providing an open-source foundation model trained exclusively on high-quality maritime literature, Llamarine paves the way for AI-driven advancements in maritime safety, efficiency, and operational decision-making.

cs.CL